Raptor (Rap) or Regulatory-Associated Protein of TOR 1 binds mTOR which controls cell growth, p70 S6 kinase α (S6K1) and the the initiation factor 4E binding protein 1 (4EBP1). The binding of Rap to mTOR is necessary for the mTOR-catayzed phosphorylation of the initiation factor binding protein
[1].
3D structures of raptor
Raptor 3D structures
References
- ↑ Chong ZZ, Shang YC, Maiese K. Cardiovascular disease and mTOR signaling. Trends Cardiovasc Med. 2011 Jul;21(5):151-5. doi: 10.1016/j.tcm.2012.04.005. PMID:22732551 doi:http://dx.doi.org/10.1016/j.tcm.2012.04.005
