Sandbox 31
From Proteopedia
| Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013. |
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Adenylate Kinase (PDB ID #: 1ake)
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Introduction
is a good little protein.
Physical Properties
Adenylate kinase is caged with .
I can add headings
This is the scene.
Structure
The of adenylate kinase shows alpha helices (cyan) and beta sheets (green) surrounding the non-hydrolysable substrate analogue (orange). A network of hold the secondary structural elements together. You can see the regular hydrogen bonding pattern in the alpha helices.
Adenylate kinase has a exterior, and a core, with additional on the interior contacting the ligand.
Active Site and Mechanism
residues within of the ligand are involved in binding the ligand or stabilizing the active site.
adenylate kinase's is highlighted in dark blue.
together you can see that the is only a fraction of the molecules involved in binding the ligand.
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Comparing the E.coli structure to
References
