From Proteopedia
proteopedia linkproteopedia link<math></math>==Human GPR40, also known as Free Fatty Acid Receptor 1 (FFAR1)==
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Background
Structure
Binding Sites
Figure 2. Second proposed binding site of GPR40. By visual inspection, a second possible binding site was proposed between transmembrane helices 3, 4, and 5 on the intracellular side.
Figure 3. Third proposed binding site of GPR40. By visual inspection, a third possible binding site was proposed between transmembrane helices 1, 2, and 7 on the extracellular side.
Ionic Charge Network
ECL2
beta sheet
Function
Clinical Relevance
Tak-875
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References