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Function of your protein
Biological relevance and broader implications
Because cancer cells increase proline numbers when THFA is present within PYCR1, it binds to areas that proline would normally bind because of THFA's similarity to proline in size, shape, and noncovalent bonds. When THFA binds to PYCR1, the ligand is able to act as an inhibitor. This could be an important finding in breast cancer research.
Important amino acids
Structural highlights
Other important features