Sodium channel blockers are drugs which impair the conduction of sodium ions (Na+) through sodium channels. See also Sodium channel blocker.
Intracellular
Drugs which block sodium channels by blocking from the intracellular side of the channel include:
Local anesthetics:
Class I antiarrhythmic agents
Various anticonvulsants: phenytoin, oxcarbazepine (derivative of carbamazepine)