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  1. 1vfn (4,985 bytes)
    11: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  2. 1hiy (4,737 bytes)
    7: ...kDat" id="ligandDat"><scene name='pdbligand=3AN:3-DEOXY+3-AMINO+ADENOSINE-5-DIPHOSPHATE'>3AN</scene></td>...
    24: ...pects. Crystallography of the protein bound to 3'-deoxy-3'-amino-ADP showed that the drug was in a distor...
  3. 2bsx (5,924 bytes)
    11: ...osine and guanosine, and to a lesser extent on 2'-deoxyguanosine and guanosine (PubMed:14982926, PubMed:1...
  4. 3pnp (2,832 bytes)
    11: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  5. 4pnp (2,779 bytes)
    11: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  6. 1cb0 (6,364 bytes)
    2: ==STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE AT 1.7 A RES...
    26: ...AP) catalyzes the reversible phosphorolysis of 5'-deoxy-5'-methylthioadenosine (MTA) to adenine and 5-met...
    28: The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A res...
    35: ...ethylthioadenosine phosphorylase 3D structures|5'-deoxy-5'-methylthioadenosine phosphorylase 3D structure...
  7. 1cg6 (6,595 bytes)
    2: ...THYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-DEOXY-5'-METHYLTHIOADENOSINE AND SULFATE AT 1.7 A RESOL...
    7: ...kDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='...
    26: ...AP) catalyzes the reversible phosphorolysis of 5'-deoxy-5'-methylthioadenosine (MTA) to adenine and 5-met...
    28: The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A res...
    35: ...[5'-deoxy-5'-methylthioadenosine phosphorylase|5'-deoxy-5'-methylthioadenosine phosphorylase]]
  8. 1m73 (4,774 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
    26: ...n human, PNP is the only route for degradation of deoxyguanosine and genetic deficiency of this enzyme le...
  9. 1pf7 (4,939 bytes)
    7: ..." id="ligandDat"><scene name='pdbligand=IMH:1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL'>...
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
    26: ...owth of malignant T-cell lines in the presence of deoxyguanosine without affecting non-T-cell tumor lines...
  10. 1pwy (4,791 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
    26: ...orylase (HsPNP) is responsible for degradation of deoxyguanosine and genetic deficiency of this enzyme le...
  11. 1q91 (4,978 bytes)
    2: ==Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor DPB...
    7: ...d="ligandDat"><scene name='pdbligand=DPB:(S)-1-[2-DEOXY-3,5-O-(1-PHOSPHONO)BENZYLIDENE-B-D-THREO-PENTOFUR...
    11: ...he 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA...
    24: ...tent nucleoside phosphonate inhibitors, (S)-1-[2'-deoxy-3',5'-O-(1-phosphono) benzylidene-beta-d-threo-pe...
    26: Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhi...
  12. 1q92 (4,986 bytes)
    2: ==Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor PMc...
    11: ...he 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA...
    24: ...tent nucleoside phosphonate inhibitors, (S)-1-[2'-deoxy-3',5'-O-(1-phosphono) benzylidene-beta-d-threo-pe...
    26: Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhi...
  13. 1rct (4,751 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
    26: ...human PNP in complex with inosine and 2('),3(')-dideoxyinosine, refined to 2.8A resolution using synchrot...
  14. 1rfg (4,587 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
    26: ...complex with guanosine (at 2.80 A resolution), 3'-deoxyguanosine (at 2.86 A resolution) and 8-azaguanine ...
  15. 1rr6 (5,299 bytes)
    7: ..." id="ligandDat"><scene name='pdbligand=IMH:1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL'>...
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  16. 1rsz (3,375 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  17. 1rt9 (3,320 bytes)
    7: ..." id="ligandDat"><scene name='pdbligand=IMH:1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL'>...
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  18. 1ula (3,507 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  19. 1ulb (3,439 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
  20. 1v2h (4,816 bytes)
    13: ...c breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of t...
    26: ...f the N-ribosidic bonds of purine nucleosides and deoxynucleosides. PNP is a target for inhibitor develop...

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