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  1. 3ska (8,512 bytes)
    15: ...emplified by initial indole lead 1 (NS5B IC(50)=0.9muM, replicon EC(50)>100muM) is described. Structu...
  2. 3ske (8,535 bytes)
    15: ...emplified by initial indole lead 1 (NS5B IC(50)=0.9muM, replicon EC(50)>100muM) is described. Structu...
  3. 4byf (4,718 bytes)
    14: ...ablish a tight interaction with 14-3-3beta (KD =0.9muM) and present the model of a double-headed myosin ...
  4. 4ctm (4,535 bytes)
    14: ...Pb). Best inhibitors were the 2-benzoylimino- (Ki=9muM) and the 2-naphthoylimino-thiazolidinones (Ki=10m...
  5. 4ctn (4,643 bytes)
    14: ...Pb). Best inhibitors were the 2-benzoylimino- (Ki=9muM) and the 2-naphthoylimino-thiazolidinones (Ki=10m...
  6. 4cto (4,550 bytes)
    14: ...Pb). Best inhibitors were the 2-benzoylimino- (Ki=9muM) and the 2-naphthoylimino-thiazolidinones (Ki=10m...
  7. 4yzu (5,056 bytes)
    16: ...ne, potency was improved 20-fold, from 2muM to 0.09muM. X-ray crystal structures were obtained for an ex...
  8. 4z0k (5,086 bytes)
    16: ...ne, potency was improved 20-fold, from 2muM to 0.09muM. X-ray crystal structures were obtained for an ex...
  9. 5noi (4,646 bytes)
    15: ...nd has a dimerization dissociation constant of 16.9muM in solution. Direct fluorescence resonance energy...
  10. 5qa4 (4,331 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  11. 5qa5 (4,356 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  12. 5qa6 (4,357 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  13. 5qa7 (4,357 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  14. 5qa8 (4,300 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  15. 5qa9 (4,363 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  16. 5qaa (4,357 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  17. 5qab (4,357 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  18. 5qac (4,354 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  19. 5qad (4,356 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...
  20. 5qae (4,355 bytes)
    14: ...ory potential in the low micromolar range (IC50=2.9muM). For these inhibitors, the complex X-ray structu...

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