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Article title matches
- Category:Ack1 (35 bytes)
1: List of pages with the keyword Ack1
Page text matches
- 1u46 (4,160 bytes)
2: ...osphorylated Kinase Domain of the Tyrosine Kinase ACK1==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t... - 1u4d (5,816 bytes)
2: ==Structure of the ACK1 Kinase Domain bound to Debromohymenialdisine==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
24: ...ates. Comparison of these structures reveals that ACK1 adopts an activated conformation independent of p...
26: ...e domains of the Cdc42-associated tyrosine kinase ACK1.,Lougheed JC, Chen RH, Mak P, Stout TJ J Biol Che... - 1u54 (5,892 bytes)
2: ...e Domains of the CDC42-associated Tyrosine Kinase ACK1 bound to AMP-PCP==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
24: ...ates. Comparison of these structures reveals that ACK1 adopts an activated conformation independent of p...
26: ...e domains of the Cdc42-associated tyrosine kinase ACK1.,Lougheed JC, Chen RH, Mak P, Stout TJ J Biol Che... - 4id7 (3,815 bytes)
2: ==ACK1 kinase in complex with the inhibitor cis-3-[8-ami...
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t... - 4hzr (3,415 bytes)
2: ==Crystal structure of Ack1 kinase domain==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t... - 4hzs (3,166 bytes)
2: ==Crystal structure of Ack1 kinase domain with C-terminal SH3 domain==
10: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t... - 3eqp (5,321 bytes)
2: ==Crystal Structure of Ack1 with compound T95==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
24: ...ve inhibitors of the nonreceptor tyrosine kinase, ACK1. These compounds arose from efforts to rigidify a...
26: ...3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors.,Kopecky DJ, Hao X, Chen Y, Fu J, Jiao... - 3eqr (5,323 bytes)
2: ==Crystal Structure of Ack1 with compound T74==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
24: ...ve inhibitors of the nonreceptor tyrosine kinase, ACK1. These compounds arose from efforts to rigidify a...
26: ...3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors.,Kopecky DJ, Hao X, Chen Y, Fu J, Jiao... - Category:Ack1 (35 bytes)
1: List of pages with the keyword Ack1 - 4ewh (4,456 bytes)
2: ==Co-crystal structure of ACK1 with inhibitor==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
14: ...imidin-4-amines, were discovered and evaluated as ACK1 inhibitors. Further structural refinement led to ...
16: ...amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors.,Jiao X, Kopecky DJ, Liu J, Liu J, Jae... - 8fe9 (3,651 bytes)
2: ==Crystal structure of Ack1 kinase K161Q mutant in complex with the selective...
12: ... cancers, we report loss-of-function mutations in Ack1 and Brk, highlighting the complexity of TK involv...
14: ...ociated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk.,Kan Y, Paung Y, Kim Y, Seeliger MA, Mill... - 2mcr (4,202 bytes)
12: ...nalysis, 2 worm peptides were selected for study: AcK1, a 51-residue peptide expressed in the anterior s... - 2md0 (4,185 bytes)
13: ...nalysis, 2 worm peptides were selected for study: AcK1, a 51-residue peptide expressed in the anterior s... - 5zxb (3,500 bytes)
2: ==Crystal structure of ACK1 with compound 10d==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t... - Tyrosine kinase 3D structures (25,487 bytes)
405: *'''Ack1 tyrosine kinase''' or activated cdc42 kinase 1
407: **[[1u46]], [[4hzr]] - hTK Ack1 kinase domain 115-389<br />
408: **[[4hzs]] - hTK Ack1 kinase+SH3 domains <br />
409: ...h]], [[4id7]], [[5zxb]], [[7kp6]], [[8hmt]] - hTK Ack1 kinase domain + inhibitor<br />
410: **[[8fe9]] - hTK Ack1 kinase domain (mutant) + inhibitor<br /> - 6vqm (3,424 bytes)
2: ==Crystal Structure Analysis of human ACK1==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t... - 7kp6 (5,433 bytes)
2: ==Structure of Ack1 kinase in complex with a selective inhibitor==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
14: ...CB-resistant tumours, which provides evidence for ACK1 enzymatic activity playing a pivotal role in gene...
16: Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase... - 7n8x (2,749 bytes)
10: ...and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signali... - 7n9y (2,749 bytes)
10: ...and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signali... - 8hmt (3,368 bytes)
2: ==The complex of ACK1 with the inhibitor 2-142==
11: [https://www.uniprot.org/uniprot/ACK1_HUMAN ACK1_HUMAN] Non-receptor tyrosine-protein and serine/t...
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