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- Herceptin - Mechanism of Action (16,532 bytes)
1: ...tal structure of extracellular domain of human HER2 complexed with Herceptin Fab (PDB entry [[1n8z]])...
2: ...re 1) Structure of the extracellular region of HER2 complexed with Herceptin Fab([[1n8z]])</span>]]
6: ...enentech: Medicines. Genentech, n.d. Web. Nov. 2012. <http://www.gene.com/gene/products/information/o...
7: === HER2 ===
9: ... the HER family. The HER family (refer to figure 2 and figure 5) are plasma membrane-bound receptors... - Ion channels (6,479 bytes)
3: ...</sup> transported units per second versus 10<sup>2</sup> to 10<sup>4</sup> molecules per second for ...
7: ...ls''' let through various cations<ref>PMID:17579562</ref>.<br />
9: ...iate- and small-conductance KCh (human SK1, rat SK2, SKCa). See: [[Potassium Channel|Potassium channe...
11: ...g ions to flow across the cell membrane<ref>PMID:12046893</ref>.<br />
23: ...-Dependent Anion Channels''' (VDAC)<ref>PMID:16787253</ref>.<br /> - User:Fadel A. Samatey/FlhBc I (8,420 bytes)
2: [[Image:Acta_Cryst_D.png|900 px]]
5: ...107/S0907444913002102 doi:10.1107/S0907444913002102] <span style="background-color:#ffff80;padding:3p...
12: ...se see [http://dx.doi.org/10.1107/S0907444913002102 the open access publication] for a more detailed ...
18: ...tional interactive molecular scenes before May 5, 2013.
21: ...ncludes coordinates for residues 229-353 (length 125, 76% of the crystallized length). The [[asymmetr... - Journal:Genes:1 (3,526 bytes)
3: ...il and Jiri Cerny</big> <ref>doi 10.3390/genes8100278</ref>
6: ... [https://dnatco.org dnatco.org] <ref>pmid 27150812</ref>.
8: ...d by the periodic occurrence of the CANA letter BB2 every 10.3 steps along the DNA strand.
17: ...the structure described by the CANA letter AAA (BB2) are highlighted in red (blue) color. - Flaps Morph for HIV Protease (8,711 bytes)
2: ...://www.uniprot.org/uniprot/P04585 P04585 (POL_HV1H2)]) that requires cutting by HIV protease in order...
4: ...otease tend to "lock" the flaps closed<ref>PMID:22291339</ref>. Mutations in HIV protease that confer...
6: ...nd '''wide open'''<ref name="processes" />. As of 2017, no ligand-free crystal structure has captured...
9: ...</scene>). The catalytic <font color="red">'''Asp 25's are red'''</font>. (Note that "wide open" is n...
10: <center>{{Template:Button_Toggle_Animation2}}</center> - Ligand-gated ion channels (ionotropic receptors) (684 bytes)
1: ...otropic glutamate receptor tetramer, GluA2, ([[3kg2]])' scene='Ionotropic_Glutamate_Receptors/Opening...
2: [[Image:IGluR Picture.png|200px|left]]
7: ...nding a ligand like a neurotransmitter<ref>PMID:15288758</ref>.<br />
8: ...ted ion channel]] <ref>doi 10.1107/S205979832000772X</ref>
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