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- 2cfb (4,714 bytes)
24: ...GSAM) are evolutionarily closely related and that ALAS may thus have evolved from GSAM. - 2bwp (4,369 bytes)
24: ..., or hamper the correct folding. The structure of ALAS completes the structural analysis of enzymes in h... - 2bwo (4,331 bytes)
24: ..., or hamper the correct folding. The structure of ALAS completes the structural analysis of enzymes in h... - 2bwn (4,507 bytes)
24: ..., or hamper the correct folding. The structure of ALAS completes the structural analysis of enzymes in h... - 1h7d (3,018 bytes)
2: ...=Solution structure of the 49 aa presequence of 5-ALAS==
13: ...irst time, that heme interacts with the HRMs of psALAS. - 1h7j (3,018 bytes)
2: ...=Solution structure of the 26 aa presequence of 5-ALAS==
13: ...irst time, that heme interacts with the HRMs of psALAS. - 8eim (3,834 bytes)
2: ==Structure of ALAS with C-terminal truncation from S. cerevisiae==
14: ...ivity. These findings suggest that the eukaryotic ALAS C-terminus has a homolog-specific role in mediati... - 5txr (2,089 bytes)
2: ==Structure of ALAS from S. cerevisiae non-covalently bound to PLP co... - 5txt (2,170 bytes)
2: ==Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae== - 9dz7 (265 bytes)
7: Description: Structure of ALAS bound to glycine from S. cerevisiae - 9dzo (270 bytes)
7: Description: Structure of ALAS bound to succinyl-CoA from S. cerevisiae - 7x98 (3,020 bytes)
14: ... half close conformation may also be conserved in ALAS family. The pre-existed close and half close conf... - User:Adéla Fejfarová/Sandbox 1 (9,657 bytes)
1: =ALAS2 in erythroid heme biosynthesis disorders=
3: ...s thorough the sequence of the enzyme lead to two ALAS2-associated blood disorders. Namely X-linked side...
7: == Physiological function of enzyme ALAS2 ==
8: ...-keeping gene expressed ubiquitously, in contrast ALAS2 (gene location Xp11.21) is specific for erythroi...
10: === ALAS role in heme biosynthesis === - ALAS2 in erythroid heme biosynthesis disorders (10,583 bytes)
1: =ALAS2 in erythroid heme biosynthesis disorders=
2: ...o isoforms of ALAS enzyme. The erythroid-specific ALAS2 located on '''chromosome X''' is expressed durin...
3: ALAS2-associated blood disorders. Namely '''X-linked s...
5: ==Physiological function of enzyme ALAS2==
6: In vertebrates, there are two genes encoding ALAS enzymes that belong to α-oxoamine synthase famil... - User:Adéla Fejfarová/Sandbox 2 (10,230 bytes)
1: =ALAS2 in erythroid heme biosynthesis disorders=
2: ...s thorough the sequence of the enzyme lead to two ALAS2-associated blood disorders. Namely X-linked side...
4: ==Physiological function of enzyme ALAS2==
5: In vertebrates, there are two genes encoding ALAS enzymes that belong
6: ...-keeping gene expressed ubiquitously, in contrast ALAS2 (gene location Xp11.21) is specific for erythroi...
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