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  1. ALDH2 (11,729 bytes)
    2: ...coholism.<ref>DOI:10.1186/1479-7364-2-2-138</ref> ALDH2 gene is 44kpbs long with 13 exons.<ref>DOI:10.107...
    7: ALDH2 enzyme functions as homotetramer where each monom...
    14: ....org/10.2210/pdb1CW3/pdb 1CW3])' scene='76/763091/Aldh2_active_site_a-chain/2'>
    15: ALDH2 plays crucial role in metabolism of ethanol and l...
    16: ...0057</ref> In addition to acetaldehyde, for which ALDH2 shows highest affinity among ALDHs, this enzyme a...

Page text matches

  1. 1o05 (5,549 bytes)
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    24: ...ree-dimensional structure of the R475Q variant of ALDH2 supports a role in subunit communication for thes...
  2. 1zum (4,429 bytes)
    2: ...tochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, Apo Form==
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    24: ...vo. Here we report the 2.1 A crystal structure of ALDH2*2. The structure shows a large disordered region ...
  3. 2onm (5,126 bytes)
    2: ...tochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+==
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    24: ...y reordered. Consistent with the structural data, ALDH2(*)2 showed a concentration-dependent increase in ...
  4. 2onn (4,700 bytes)
    10: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    23: ...y reordered. Consistent with the structural data, ALDH2(*)2 showed a concentration-dependent increase in ...
  5. 2ono (4,723 bytes)
    10: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    23: ...y reordered. Consistent with the structural data, ALDH2(*)2 showed a concentration-dependent increase in ...
  6. 2onp (5,108 bytes)
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    24: ...y reordered. Consistent with the structural data, ALDH2(*)2 showed a concentration-dependent increase in ...
  7. 1ag8 (5,148 bytes)
    10: [https://www.uniprot.org/uniprot/ALDH2_BOVIN ALDH2_BOVIN]
    23: ...ossmann-type fold, the coenzyme-binding region of ALDH2 binds NAD+ in a manner not seen in other NAD+-bin...
  8. 1bi9 (4,371 bytes)
    24: ...ucture of a mitochondrial aldehyde dehydrogenase (ALDH2) as a model. Unlike what has been described for t...
  9. 1bxs (4,892 bytes)
    24: ...ug disulfiram reacts more rapidly with ALDH1 than ALDH2. The disorder of Glu268 and the observation that ...
  10. 2vle (4,247 bytes)
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    24: ...esign of improved ALDH2. The structure of daidzin/ALDH2 in complex at 2.4 A resolution shows the isoflavo...
  11. 2wme (6,171 bytes)
    24: ...idge between E179 (E195 of ALDH2) and R40 (E53 of ALDH2) moves the carboxylate group of the former away f...
  12. 3inj (4,211 bytes)
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    24: ...d-type enzyme and how it restores the activity of ALDH2*2 by acting as a structural chaperone.
  13. 3inl (2,632 bytes)
    2: ...tochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1==
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
  14. Alcohol dehydrogenase (17,576 bytes)
    14: *[[ALDH2]]<br />
  15. Aldehyde dehydrogenase (3,247 bytes)
    23: ...Inhibitors can include pesticides. Mitochondrial ALDH2 deficiency causes accumulation of acetaldehyde in...
  16. 3sz9 (3,473 bytes)
    2: ==Crystal structure of human ALDH2 modified with the beta-elimination product of Ald...
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
  17. Aldehyde dehydrogenase 3D structures (14,215 bytes)
    43: **[[8shs]] – hALDH2 – Cryo EM<br />
    44: **[[3n80]], [[1o05]], [[4kwf]] – hALDH2 residues 18-517<BR />
    45: **[[3n81]], [[2onn]], [[2ono]], [[1zum]] – hALDH2 residues 18-517 (mutant) <BR />
    48: *ALDH2 binary complex
    50: **[[3inj]], [[3inl]], [[4kwg]] - hALDH2 residues 18-517 + agonist<BR />
  18. 4kwf (3,480 bytes)
    2: ==Crystal Structure Analysis of ALDH2+ALDiB33==
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
    14: ...leophile, Cys243, in ALDH3A1 but not in ALDH2. In ALDH2, the 3-keto group is surrounded by the adjacent C...
  19. 4kwg (1,864 bytes)
    2: ==Crystal Structure Analysis of ALDH2+ALDiB13==
    11: [https://www.uniprot.org/uniprot/ALDH2_HUMAN ALDH2_HUMAN]
  20. 4l1o (3,892 bytes)
    14: ...leophile, Cys243, in ALDH3A1 but not in ALDH2. In ALDH2, the 3-keto group is surrounded by the adjacent C...

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