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- Andrew Helmerich Sandbox 1 (10,787 bytes)
2: ...Bound to Amylin' scene='10/1038828/Entire_protein_scene/7'>
4: ...dely distributed throughout the central nervous system <ref name="Hay">PMID:26071095</ref>.
5: ...ifying_protein receptor activity modifying proteins] (RAMP 1,2, or 3)<ref name="Cao">PMID:35324283</r...
6: ...main in place. More importantly, the RAMP restricts the dynamic movement of the extracellular domain ...
7: ==Structure== - User:Andrew Dowd (217 bytes)
1: * Full Real Name: Andrew Dowd
3: * Position:Research Scientist
5: * Institution (NO ABBREVIATIONS): Unilever R&D
7: ... State/Province, Country: Bebington, Wirral/Merseyside
9: * Field of Expertise or Study: Biotechnology - User:Andrew Arrowsmith (125 bytes)
1: Undergrad at University of Mcgill Science.
2: .... student for The Structural Genomics Consortium (SGC). - User:Andrew Arrowsmith/3CLZ (266 bytes)
2: ...ains 1 (UHRF1/ICBP90/NP95) in complex with double-stranded DNA.
3: <table border="2" cellpadding="2" cellspacing="2">
5: {{STRUCTURE_3clz| PDB=3clz | SCENE= }} - User:Andrew Koelper (257 bytes)
1: *[[User:Andrew Koelper/Sandbox 1]]
2: * Full Real Name:Andrew Koelper
4: * Position:Student
6: * Institution (NO ABBREVIATIONS):Butler University
8: ...vince, Country:Indianapolis, Indiana, United States - User:Andrew Burwash (293 bytes)
1: * Full Real Name: Andrew Burwash
3: ...udent and Member of SMART (Students Modelling a Research Topic) Team.
5: * Institution (NO ABBREVIATIONS): Ashbury College
7: * City, State/Province, Country: Ottawa, Ontario, Canada
9: * Field of Expertise or Study: Biomolecular Modelling - User:Andrew Rebeyka (193 bytes)
1: ...ulty working towards a degree in biomedical studies. - User:Andrew Jay Fielding (453 bytes)
1: ...Chemistry and Biochemistry from Idaho State University - User:Andrew Winslow (77 bytes)
1: ...in the Computer Science Department at Tufts University. - User:Andrew Gallant (186 bytes)
1: ... Science degree in Computer Science and Mathematics. - User:Andrew Gilman (73 bytes)
1: ...nt undergrad Che 361, biochemistry student at Wabash College. - User:Andrew Alexander (72 bytes)
1: ...rgraduate student majoring in Biochemistry at Wabash College. - User:Andrew Swart (54 bytes)
1: Biochemistry major in my junior year at Wabash College - User:Andrew Menke (95 bytes)
1: I am a graduate student at the University of Vermont in the Cell and Molecular Biology p... - User:Napoleon Andrew (67 bytes)
1: ...d year pharmacy student at Howard University in Washington, DC - User:Andrew C. Vinal (964 bytes)
1: ...to computerize laboratory equipment and conduct research. - User:Andrew Brockfield (66 bytes)
1: ...nior in Microbiology at University of California, Santa Barbara. - User:Andrew R. Chandra (224 bytes)
1: ... Brook in the United States of America located in Stony Brook, New York.
3: [[User: Conor Finnegan/workbench]] - User:Andrew B. Wills (340 bytes)
1: [[User:Andrew Wills/Sandbox 1]]
2: * Full Real Name:Andrew B. Wills
4: * Position:Student in BCMB 402
6: * Institution :The University of Tennessee Knoxville
8: ...ce, Country:Knoxville, Tennessee, The United States of America - User:Andrew Wills/Sandbox 1 (10,521 bytes)
3: {{STRUCTURE_1diz| PDB=1diz | SCENE= }}
5: ...STRUCTURE OF E. COLI 3-METHYLADENINE DNA GLYCOSYLASE (ALKA) COMPLEXED WITH DNA===
9: ...E (ALKA) COMPLEXED WITH DNA (PDB entry [[1diz]])' scene=''>
12: ...Jeremy, Tymoczko John, and Lubert Stryer. Biochemistry. 6th. New York: W.H. Freeman and Company, 2007...
16: ==Key Structures==
Page text matches
- 1e85 (4,120 bytes)
2: ...ans - reduced structure with NO bound to proximal side of heme==
3: ...'[[1e85]], [[Resolution|resolution]] 1.35Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=1E85 FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> - 1e86 (4,123 bytes)
2: ...idans - reduced structure with CO bound to distal side of heme==
3: ...'[[1e86]], [[Resolution|resolution]] 1.95Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=1E86 FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> - 1e83 (4,030 bytes)
2: ...hrome c' from Alcaligenes xylosoxidans - oxidized structure==
3: ...'[[1e83]], [[Resolution|resolution]] 2.05Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=1E83 FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> - 1e84 (4,028 bytes)
2: ...chrome c' from Alcaligenes xylosoxidans - reduced structure==
3: ...'[[1e84]], [[Resolution|resolution]] 1.90Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=1E84 FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> - Mu Opioid Receptor Bound to a Morphinan Antagonist (11,597 bytes)
3: ... Their Ligands." Current Topics in Medicinal Chemistry 4.1 (2004): 1-17.</ref>
4: ... Cl- ion (PDB entry [[4dkl]])' scene=4dkl/Overall_structure/1''>
6: == Overview of Structure ==
7: ...d_tm6_dimer_form/1'>TM5 and TM6 Dimer Interface.</scene>
9: ...esent and may help to stabilize the receptor in its inactivated form. - Andrew Helmerich Sandbox 1 (10,787 bytes)
2: ...Bound to Amylin' scene='10/1038828/Entire_protein_scene/7'>
4: ...dely distributed throughout the central nervous system <ref name="Hay">PMID:26071095</ref>.
5: ...ifying_protein receptor activity modifying proteins] (RAMP 1,2, or 3)<ref name="Cao">PMID:35324283</r...
6: ...main in place. More importantly, the RAMP restricts the dynamic movement of the extracellular domain ...
7: ==Structure== - 1ete (3,780 bytes)
2: ==CRYSTAL STRUCTURE OF THE FLT3 LIGAND==
3: ...'[[1ete]], [[Resolution|resolution]] 2.20Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=1ETE FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> - User:Andrew Dowd (217 bytes)
1: * Full Real Name: Andrew Dowd
3: * Position:Research Scientist
5: * Institution (NO ABBREVIATIONS): Unilever R&D
7: ... State/Province, Country: Bebington, Wirral/Merseyside
9: * Field of Expertise or Study: Biotechnology - Insulin receptor (23,714 bytes)
7: ==Insulin Receptor==
8: ...molecules bound in green.' scene='83/839263/Intro_scene/2'>
11: ...e intracellular signaling cascades.<ref name="Meyts"/>
13: ...heimer's, type II diabetes, and cancer.<ref name="Scapin"> DOI:10.1038/nature26153</ref>
15: ... role of the receptor in crucial cellular processes. - Herceptin - Mechanism of Action (16,532 bytes)
1: ...omplexed with Herceptin Fab (PDB entry [[1n8z]])' scene=''>
2: ...n of HER2 complexed with Herceptin Fab([[1n8z]])</span>]]
4: == '''Basics''' ==
6: ... Web. Nov. 2012. <http://www.gene.com/gene/products/information/oncology/herceptin/timeline.html>.</r...
9: ...ain an extracellular ligand-binding domain, a transmembrane domain, and an intracellular domain <ref ... - 2b0f (7,076 bytes)
2: ...MR Structure of the Human Rhinovirus 3C Protease (serotype 14) with covalently bound Ace-LEALFQ-ethyl...
3: ...='2b0f' size='340' side='right'caption='[[2b0f]]' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=2B0F FirstGlance]. <br>
6: ...d:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> - 2bk1 (4,351 bytes)
2: ...d by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map==
3: ...[[2bk1]], [[Resolution|resolution]] 29.00Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=2BK1 FirstGlance]. <br>
6: ...d="methodDat">Electron Microscopy, [[Resolution|Resolution]] 29Å</td></tr> - 2bk2 (4,354 bytes)
2: ...d by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map==
3: ...[[2bk2]], [[Resolution|resolution]] 28.00Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=2BK2 FirstGlance]. <br>
6: ...d="methodDat">Electron Microscopy, [[Resolution|Resolution]] 28Å</td></tr> - 2in2 (6,575 bytes)
2: ...tructure of the Apo Human Rhinovirus 3C Protease (serotype 14)==
3: ...='2in2' size='340' side='right'caption='[[2in2]]' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=2IN2 FirstGlance]. <br>
6: ...d:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> - User:Brian Conner (333 bytes)
1: * Full Real Name: Brian Andrew Conner
3: * Position: Student
5: ...on (NO ABBREVIATIONS): North Carolina State University
7: ...ce, Country: Raleigh, North Carolina, United States
9: ...chemistry. I will graduate with a B.S. in Biochemistry in May 2014 - 9hrk (4,071 bytes)
2: ...tus in the ferrous state (single crosslink from Lys)==
3: ...'[[9hrk]], [[Resolution|resolution]] 1.33Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=9HRK FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33Å</td></tr> - 9hs6 (4,169 bytes)
2: ...Methyloccocus capsulatus (double crosslink from Lys), aged==
3: ...'[[9hs6]], [[Resolution|resolution]] 1.77Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=9HS6 FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> - 9hs4 (4,163 bytes)
2: ...Methyloccocus capsulatus (double crosslink from Lys)==
3: ...'[[9hs4]], [[Resolution|resolution]] 1.66Å' scene=''>
4: == Structural highlights ==
5: ... [https://proteopedia.org/fgij/fg.htm?mol=9HS4 FirstGlance]. <br>
6: ... id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> - Ann taylor sandbox (2,042 bytes)
1: ==Andrew Gilman Serine Protease 2AGG 118==
3: ...atalyse the hydrolysis of peptide bonds in proteins.
6: ...main 2 beta barrel, and the activation site is close next to it.
8: ...omain 2beta barrel, and the activation site is close next to it.
18: Trypsin BPT1 complex - Student Projects (6,606 bytes)
1: ... use the ''Find'' function of your browser (Windows: Ctrl-F; Mac: Cmd-F).
5: ...eflect new structural results. Student contributors are acknowledged on each page.
7: ...rahydrofolate reductase]] and [[Thymidylate synthase]].
11: ... page [[Tutorial:The opioid receptor, a molecular switch]].
13: ...anish, includes English abstract. Published also as http://hdl.handle.net/10017/27238)''
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