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Article title matches
- Category:Bace1 (36 bytes)
1: List of pages with the keyword Bace1 - Category:Bace1 inhibitor (46 bytes)
1: List of pages with the keyword Bace1 inhibitor - Category:Bace1 protease inhibitor (55 bytes)
1: List of pages with the keyword Bace1 protease inhibitor - Beta Secretase (BACE1) 1SGZ (16,799 bytes)
1: ...CE''' or '''Memapsin 2''', is encoded by the gene BACE1. Beta-secretase is a proteolytic, transmembrane ...
3: ...; Wong, P.; Macklin, W. B.; Trapp, B. D.; Yan, R. Bace1 Modulates Myelination in the Central and Peripher...
14: BACE1 is a type-1 integral membrane glycoprotein that i...
16: ...Nukina, N. Crystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid Beta Protein P...
18: ...artate residues that reside in the active site of BACE1 are <scene name='72/728011/Asp_32_228_pink/1'>Asp... - Category:Bace1-inhibitor complex (54 bytes)
1: List of pages with the keyword Bace1-inhibitor complex
Page text matches
- 4i1c (3,242 bytes)
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...ly selective, potent and novel BACE1 inhibitor 8 (BACE1 Alpha assay IC50=8nM) was made from a weak muM po...
16: ...thesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors.,Xu YZ, Yuan S, Bowers S, Hom RK, Chan... - 3zkq (4,628 bytes)
14: ...Alzheimer's disease target enzyme beta-secretase (BACE1). High-resolution BACE2 structures would contribu... - 4h3j (4,132 bytes)
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...ulted in analogues with low nanomolar potency for BACE1. In particular, optimization of the prime side su...
16: ...opyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a... - 2ewy (5,208 bytes)
24: ...tures that may facilitate the design of selective BACE1 or BACE2 inhibitors. - 4h3f (4,154 bytes)
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...ulted in analogues with low nanomolar potency for BACE1. In particular, optimization of the prime side su...
16: ...opyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a... - 2g31 (4,537 bytes)
10: ...nd sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing... - 2p4e (5,805 bytes)
13: ...n the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway. Inhibits epitheli... - 2p83 (3,912 bytes)
2: ... isophthalamide S2 hydroxyethylamine inhibitor of BACE1==
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
24: ... design and synthesis of a novel series of potent BACE1 hydroxyethylamine inhibitors. These inhibitors fe...
26: ...isophthalamide S2 hydroxyethylamine inhibitors of BACE1.,Kortum SW, Benson TE, Bienkowski MJ, Emmons TL, ... - 2pmw (5,408 bytes)
13: ...n the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway. Inhibits epitheli... - 2qtw (5,906 bytes)
13: ...n the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway. Inhibits epitheli... - 4h3g (4,156 bytes)
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...ulted in analogues with low nanomolar potency for BACE1. In particular, optimization of the prime side su...
16: ...opyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a... - 4i12 (2,859 bytes)
12: ...ly selective, potent and novel BACE1 inhibitor 8 (BACE1 Alpha assay IC50=8nM) was made from a weak muM po...
14: ...thesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors.,Xu YZ, Yuan S, Bowers S, Hom RK, Chan... - 4j1i (3,735 bytes)
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...d oxazine 89, a potent and highly brain penetrant BACE1 inhibitor, was able to reduce significantly CSF A...
16: beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable f... - 4ivs (3,792 bytes)
2: ==Crystal structure of BACE1 with its inhibitor==
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...s redefined as a potential binding site for later BACE1 inhibitor design.
16: ...f indole acylguanidines as potent beta-secretase (BACE1) inhibitors.,Zou Y, Li L, Chen W, Chen T, Ma L, W... - 4ivt (3,874 bytes)
2: ==Crystal structure of BACE1 with its inhibitor==
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...s redefined as a potential binding site for later BACE1 inhibitor design.
16: ...f indole acylguanidines as potent beta-secretase (BACE1) inhibitors.,Zou Y, Li L, Chen W, Chen T, Ma L, W... - 3zkx (4,972 bytes)
14: ...Alzheimer's disease target enzyme beta-secretase (BACE1). High-resolution BACE2 structures would contribu... - 3zkm (4,664 bytes)
14: ...Alzheimer's disease target enzyme beta-secretase (BACE1). High-resolution BACE2 structures would contribu... - 3zkn (4,850 bytes)
14: ...Alzheimer's disease target enzyme beta-secretase (BACE1). High-resolution BACE2 structures would contribu... - 3zks (4,635 bytes)
14: ...Alzheimer's disease target enzyme beta-secretase (BACE1). High-resolution BACE2 structures would contribu... - 3zov (4,582 bytes)
11: [https://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN] Responsible for the proteolytic processing...
14: ...Alzheimer's disease target enzyme beta-secretase (BACE1). High-resolution BACE2 structures would contribu...
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