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- Category:Blac 00780 (41 bytes)
1: List of pages with the keyword Blac_00780 - User:Lizun Xin/Mtb BlaC Inhibition (7,590 bytes)
1: ...<scene name='87/871911/Asymmetric_unit_of_blac/4'>BlaC</scene> protein in ''Mtb''. <StructureSection loa...
14: ...to accommodate various β-lactams. As the size of BlaC active is relatively large, the desired inhibitor...
16: ...r. Therefore, β-lactam inhibitor can inhibit the BlaC active site and allowing β-lactams to inhibit ce...
19: ...w</scene>. Due to the size and flexibility of the BlaC active site, various ß-lactam antibiotics can be...
27: ...iew</scene>, amoxicillin is covalently bounded to BlaC in the active site. - Category:Blac (35 bytes)
1: List of pages with the keyword Blac
Page text matches
- 3zhh (3,834 bytes)
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
14: ...ctive site that regulates substrate hydrolysis by BlaC. Moreover, our results suggest that directed evol... - 2gdn (4,387 bytes)
10: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
23: ... relatively poor inhibitor of the M. tuberculosis BlaC (K(i) = 2.4 microM). The crystal structure of the... - 9qi6 (2,365 bytes)
2: ==Structure of I105R BlaC from Mycobacterium tuberculosis bound to the tran...
11: [https://www.uniprot.org/uniprot/BLAC_MYCBO BLAC_MYCBO] Extended spectrum beta-lactamase (ESBL) th... - 9qi7 (2,369 bytes)
2: ==Crystal structure of I105R mutant of BlaC from Mycobacterium tuberculosis in complex with a...
11: [https://www.uniprot.org/uniprot/BLAC_MYCBO BLAC_MYCBO] Extended spectrum beta-lactamase (ESBL) th... - 9qi3 (346 bytes)
7: ...Crystal structure of I105Y/S130G double mutant of BlaC from Mycobacterium tuberculosis - 2g9w (4,680 bytes)
24: ...beta-lactam antibiotics (rv1845c, rv1846c-rv1847; blaC-sigC); two encode membrane proteins of unknown fu... - 3cg5 (3,997 bytes)
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
24: ...t from hydrolysis. The irreversible inhibition of BlaC suggests that treatment of M. tuberculosis with a... - 3dwz (4,305 bytes)
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
24: ...e the three-dimensional structure of the covalent BlaC-meropenem covalent complex at 1.8 angstrom resolu... - 3iqa (4,999 bytes)
2: ==Crystal Structure of BlaC covalently bound with Doripenem==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
24: ...rystal revealed an isomerization occurring in the BlaC-ertapenem adduct in which the original Delta(2)-p... - 4jlf (3,913 bytes)
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
14: ...ll likely not arise from structural alteration of BlaC, therefore establishing confidence that this ther...
16: ... in the Mycobacterium tuberculosis beta-Lactamase BlaC lead to clavulanate resistance?: a biochemical ra... - 3m6b (5,029 bytes)
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
24: ...rystal revealed an isomerization occurring in the BlaC-ertapenem adduct in which the original Delta(2)-p... - 3m6h (4,984 bytes)
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
24: ...rystal revealed an isomerization occurring in the BlaC-ertapenem adduct in which the original Delta(2)-p... - 3n6i (1,860 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with 6-aminopenicillian==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] - 3n7w (1,876 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Amoxicillin==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] - 3n8l (1,885 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Ampicillin==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] - 3n8r (1,891 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Carbenicillin==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] - 3n8s (3,190 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Cefamandole==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
14: ... have prepared the K73A and E166A mutant forms of BlaC and have determined the structures of the Michael... - 3nbl (1,863 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Cefuroxime==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] - 3nc8 (1,876 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Mecillinam==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU] - 3nck (1,835 bytes)
2: ==Crystal Structure of BlaC-E166A covalently bound with Nafcillin==
11: [https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
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