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Article title matches
- Category:Coagulation/crystal structure/heparin-binding site/ hirudin/thrombin inhibitor (109 bytes)
1: ... structure/heparin-binding site/ hirudin/thrombin inhibitor - Category:Blood coagulation inhibitor (58 bytes)
1: List of pages with the keyword Blood coagulation inhibitor - Category:Inhibitor of blood coagulation (61 bytes)
1: List of pages with the keyword Inhibitor of blood coagulation - Category:Coagulation factor inhibitor (59 bytes)
1: List of pages with the keyword Coagulation factor inhibitor - Category:Coagulation inhibitor (52 bytes)
1: List of pages with the keyword Coagulation inhibitor - Category:Fxa coagulation factor inhibitor (63 bytes)
1: ... of pages with the keyword Fxa coagulation factor inhibitor - Category:Blood coagulation/hydrolase inhibitor (68 bytes)
1: ...ages with the keyword Blood coagulation/hydrolase inhibitor - Category:Blood coagulation-inhibitor (58 bytes)
1: List of pages with the keyword Blood coagulation-inhibitor - Category:Blood coagulation-hydrolase inhibitor complex (76 bytes)
1: ...ages with the keyword Blood coagulation-hydrolase inhibitor complex - Category:Blood coagulation-inhibitor complex (66 bytes)
1: List of pages with the keyword Blood coagulation-inhibitor complex - Category:Coagulation blood inhibitor (58 bytes)
1: List of pages with the keyword Coagulation blood inhibitor
Page text matches
- 2cn0 (7,541 bytes)
2: ...lex of Recombinant Human Thrombin with a Designed Inhibitor==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...s hydrophobic pocket, although the potency of the inhibitors was found to be modulated by steric rather than ...
28: ...s and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p po... - 1ad8 (7,631 bytes)
2: ==COMPLEX OF THROMBIN WITH AND INHIBITOR CONTAINING A NOVEL P1 MOIETY==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...ved following the administration of some thrombin inhibitors have been linked to the positively charged guani...
28: ... design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.,Malikayil JA, Burkh... - 2cf9 (7,729 bytes)
2: ==Complex of recombinant human thrombin with an inhibitor==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...nds. Whereas the benzyl substituents in the imide inhibitors are sufficiently close (< or =3.5 Angstroms) ...
28: ...ge differences between tricyclic imide and lactam inhibitors.,Schweizer E, Hoffmann-Roder A, Olsen JA, Seiler... - 2cf8 (7,737 bytes)
2: ==Complex of recombinant human thrombin with an inhibitor==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...nds. Whereas the benzyl substituents in the imide inhibitors are sufficiently close (< or =3.5 Angstroms) ...
28: ...ge differences between tricyclic imide and lactam inhibitors.,Schweizer E, Hoffmann-Roder A, Olsen JA, Seiler... - 1awf (7,921 bytes)
2: ==NOVEL COVALENT THROMBIN INHIBITOR FROM PLANT EXTRACT==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...clusion of water for deacylation. The acyl-enzyme inhibitor hydroxyl is properly positioned for nucleophilic ...
28: Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and... - 1awh (7,597 bytes)
2: ==NOVEL COVALENT THROMBIN INHIBITOR FROM PLANT EXTRACT==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...clusion of water for deacylation. The acyl-enzyme inhibitor hydroxyl is properly positioned for nucleophilic ...
28: Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and... - 1tbz (7,587 bytes)
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...ng 2-ketothiazole group was added to the thrombin inhibitor-like framework of dansylarginine N-(3-ethyl-1,5-p...
28: ...l structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.,Matthews JH, Kr... - 1a8b (3,899 bytes)
11: ...-specific complex, which is involved in the blood coagulation cascade.
24: ...s such as annexins, protein kinase C, and certain coagulation proteins. Crystal structures of Ca(2+)-annexin V ... - 1a8a (3,887 bytes)
11: ...-specific complex, which is involved in the blood coagulation cascade.
24: ...s such as annexins, protein kinase C, and certain coagulation proteins. Crystal structures of Ca(2+)-annexin V ... - 8bo7 (5,203 bytes)
2: ...OR XI PROTEASE DOMAIN IN COMPLEX WITH ACTIVE SITE INHIBITOR 34==
13: ...he middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
16: ... identify an orally bioavailable, reversible FXIa inhibitor. Using a protein structure-based de novo design a...
18: ...ward Asundexian (BAY 2433334), an Oral Factor XIa Inhibitor for the Prevention and Treatment of Thromboemboli... - 1ai8 (8,605 bytes)
2: ...ITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...n) and is similarly not involved in substrate and inhibitor binding. Thrombin possesses an exceptionally larg... - 1w3w (4,030 bytes)
11: ...-specific complex, which is involved in the blood coagulation cascade. - 1a46 (6,630 bytes)
2: ... COMPLEXED WITH HIRUGEN AND A BETA-STRAND MIMETIC INHIBITOR==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...phic R-values between 0.148 and 0.164. Two of the inhibitors have an alpha-ketoamide functionality at the sci...
28: ...nd structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.,St Charles R, Matthews JH, Zhang E,... - 1a4w (7,410 bytes)
2: ...L STRUCTURES OF THROMBIN WITH THIAZOLE-CONTAINING INHIBITORS: PROBES OF THE S1' BINDING SITE==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...ng 2-ketothiazole group was added to the thrombin inhibitor-like framework of dansylarginine N-(3-ethyl-1,5-p...
28: ...l structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.,Matthews JH, Kr... - 1b5g (6,636 bytes)
2: ...IN COMPLEXED WITH NOVEL SYNTHETIC PEPTIDE MIMETIC INHIBITOR AND HIRUGEN==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...phic R-values between 0.148 and 0.164. Two of the inhibitors have an alpha-ketoamide functionality at the sci...
28: ...nd structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.,St Charles R, Matthews JH, Zhang E,... - 1fax (4,912 bytes)
2: ==COAGULATION FACTOR XA INHIBITOR COMPLEX==
26: ...ng site (S4) of fXa. Unlike the large majority of inhibitor complexes with serine proteinases, Gly-216 (S3) d... - 2bmg (5,660 bytes)
26: ...and reasonable activity estimations for novel fXa inhibitors. - 2c4f (5,766 bytes)
13: ...7_HUMAN] Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in ...
26: ...dicates that amides at this position may increase inhibitor binding affinity through interactions with the S1...
28: The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex--Part 2.,Kohrt JT,... - 5gds (8,181 bytes)
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...igh potency multisite-directed synthetic thrombin inhibitors. - 1h8i (7,072 bytes)
2: ...uman alpha-thrombin with a tripeptide phosphonate inhibitor.==
11: ...org/entry/613679 613679]. It is a very rare blood coagulation disorder characterized by mucocutaneous bleeding ...
26: ...suggest that the covalent bond formed between the inhibitor's phosphorus atom and O(gamma) of Ser195 proceeds...
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