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Article title matches

  1. Category:Cuozzo JW (40 bytes)
    1: List of pages with the keyword Cuozzo JW
  2. Category:Cuozzo, J W (42 bytes)
    1: List of pages with the keyword Cuozzo, J W

Page text matches

  1. 8try (5,051 bytes)
    2: ...cture of Mtb Pks13 Thioesterase domain in complex with inhibitor X20348==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TRY OCA]. For a...
    8: ...pdb/explore.do?structureId=8try RCSB], [https://www.ebi.ac.uk/pdbsum/8try PDBsum], [https://prosat.h-...
    11: ...KS domain catalyzes the condensation between the two loaded fatty acyl chains to produce an alpha-alk...
    14: ... infection. These findings and assay developments will aid in the advancement of TB drug discovery.
  2. 8tqv (5,082 bytes)
    2: ...cture of Mtb Pks13 Thioesterase domain in complex with inhibitor X20403==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TQV OCA]. For a...
    8: ...pdb/explore.do?structureId=8tqv RCSB], [https://www.ebi.ac.uk/pdbsum/8tqv PDBsum], [https://prosat.h-...
    11: ...KS domain catalyzes the condensation between the two loaded fatty acyl chains to produce an alpha-alk...
    14: ... infection. These findings and assay developments will aid in the advancement of TB drug discovery.
  3. 8tr4 (5,029 bytes)
    2: ...cture of Mtb Pks13 Thioesterase domain in complex with inhibitor X20404==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TR4 OCA]. For a...
    8: ...pdb/explore.do?structureId=8tr4 RCSB], [https://www.ebi.ac.uk/pdbsum/8tr4 PDBsum], [https://prosat.h-...
    11: ...KS domain catalyzes the condensation between the two loaded fatty acyl chains to produce an alpha-alk...
    14: ... infection. These findings and assay developments will aid in the advancement of TB drug discovery.
  4. 3ha6 (5,967 bytes)
    2: ==Crystal structure of aurora A in complex with TPX2 and compound 10==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HA6 OCA]. For a...
    8: ...pdb/explore.do?structureId=3ha6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ha6 PDBsum], [https://prosat.h-...
    11: ...ing and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1)...
    16: ...script "/wiki/ConSurf/ha/3ha6_consurf.spt"</scriptWhenChecked>
  5. 3ha8 (9,703 bytes)
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HA8 OCA]. For a...
    8: ...pdb/explore.do?structureId=3ha8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ha8 PDBsum], [https://prosat.h-...
    11: ...ion. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrint...
    16: ...script "/wiki/ConSurf/ha/3ha8_consurf.spt"</scriptWhenChecked>
    17: ...tensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
  6. Category:Cuozzo JW (40 bytes)
    1: List of pages with the keyword Cuozzo JW
  7. 5g0s (4,195 bytes)
    2: ==InhA in complex with a DNA encoded library hit==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G0S OCA]. For a...
    8: ...pdb/explore.do?structureId=5g0s RCSB], [https://www.ebi.ac.uk/pdbsum/5g0s PDBsum], [https://prosat.h-...
    11: [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
    14: ...A that do not require activation by KatG, many of which had bactericidal activity in cell-based assay...
  8. 5g0t (4,158 bytes)
    2: ==InhA in complex with a DNA encoded library hit==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G0T OCA]. For a...
    8: ...pdb/explore.do?structureId=5g0t RCSB], [https://www.ebi.ac.uk/pdbsum/5g0t PDBsum], [https://prosat.h-...
    11: [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
    14: ...A that do not require activation by KatG, many of which had bactericidal activity in cell-based assay...
  9. 5g0u (4,133 bytes)
    2: ==InhA in complex with a DNA encoded library hit==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G0U OCA]. For a...
    8: ...pdb/explore.do?structureId=5g0u RCSB], [https://www.ebi.ac.uk/pdbsum/5g0u PDBsum], [https://prosat.h-...
    11: [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
    14: ...A that do not require activation by KatG, many of which had bactericidal activity in cell-based assay...
  10. 5g0v (4,176 bytes)
    2: ==InhA in complex with a DNA encoded library hit==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G0V OCA]. For a...
    8: ...pdb/explore.do?structureId=5g0v RCSB], [https://www.ebi.ac.uk/pdbsum/5g0v PDBsum], [https://prosat.h-...
    11: [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
    14: ...A that do not require activation by KatG, many of which had bactericidal activity in cell-based assay...
  11. 5g0w (4,231 bytes)
    2: ==InhA in complex with a DNA encoded library hit==
    3: ... load='5g0w' size='340' side='right'caption='[[5g0w]], [[Resolution|resolution]] 1.79&Aring;' scene='...
    5: ...> use [https://proteopedia.org/fgij/fg.htm?mol=5G0W FirstGlance]. <br>
    8: ...ps://prosat.h-its.org/prosat/prosatexe?pdbcode=5g0w ProSAT]</span></td></tr>
    11: [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
  12. 5ku9 (4,624 bytes)
    2: ==Crystal structure of MCL1 with compound 1==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KU9 OCA]. For a...
    8: ...pdb/explore.do?structureId=5ku9 RCSB], [https://www.ebi.ac.uk/pdbsum/5ku9 PDBsum], [https://prosat.h-...
    11: ...oliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Iso...
    14: ...uM, and induces cleaved caspase-3 in MV4-11 cells with an IC50 of 3 muM after 6 h.
  13. 5mes (4,555 bytes)
    2: ==MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MES OCA]. For a...
    8: ...pdb/explore.do?structureId=5mes RCSB], [https://www.ebi.ac.uk/pdbsum/5mes PDBsum], [https://prosat.h-...
    11: ...oliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Iso...
    14: ...uM, and induces cleaved caspase-3 in MV4-11 cells with an IC50 of 3 muM after 6 h.
  14. 5mev (4,542 bytes)
    2: ==MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 21==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MEV OCA]. For a...
    7: ...25}]HEXACOSA-20,22,24-TRIENE-3,7,15,26-TETRONE'>7LW</scene></td></tr>
    8: ...pdb/explore.do?structureId=5mev RCSB], [https://www.ebi.ac.uk/pdbsum/5mev PDBsum], [https://prosat.h-...
    11: ...oliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Iso...
  15. 5u9d (6,085 bytes)
    2: ...th a novel binding mode using parallel selections with a DNA-encoded chemical library==
    5: ...graphic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U9D OCA]. For a...
    8: ...pdb/explore.do?structureId=5u9d RCSB], [https://www.ebi.ac.uk/pdbsum/5u9d PDBsum], [https://prosat.h-...
    11: ... cases XLA is inherited together with isolated growth hormone deficiency (IGHD).
    13: ...nctional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to...
  16. Category:Cuozzo, J W (42 bytes)
    1: List of pages with the keyword Cuozzo, J W
  17. 6w35 (3,941 bytes)
    2: ==A new Autotaxin Inhibitor for the Treatment of Idiopath...
    3: ...on load='6w35' size='340' side='right'caption='[[6w35]], [[Resolution|resolution]] 1.98&Aring;' scene...
    5: .../b> use [https://proteopedia.org/fgij/fg.htm?mol=6W35 FirstGlance]. <br>
    8: ...ttps://prosat.h-its.org/prosat/prosatexe?pdbcode=6w35 ProSAT]</span></td></tr>
    12: ...fully completing IND-enabling studies, compound 1 was approved by the FDA for a Phase I clinical tria...
  18. 6w44 (3,761 bytes)
    2: ==Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4==
    3: ...on load='6w44' size='340' side='right'caption='[[6w44]], [[Resolution|resolution]] 1.64&Aring;' scene...
    5: .../b> use [https://proteopedia.org/fgij/fg.htm?mol=6W44 FirstGlance]. <br>
    8: ...ttps://prosat.h-its.org/prosat/prosatexe?pdbcode=6w44 ProSAT]</span></td></tr>
    11: ...ve on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
  19. 6w45 (3,788 bytes)
    2: ==Crystal structure of HAO1 in complex with biaryl acid inhibitor - compound 3==
    3: ...on load='6w45' size='340' side='right'caption='[[6w45]], [[Resolution|resolution]] 1.70&Aring;' scene...
    5: .../b> use [https://proteopedia.org/fgij/fg.htm?mol=6W45 FirstGlance]. <br>
    8: ...ttps://prosat.h-its.org/prosat/prosatexe?pdbcode=6w45 ProSAT]</span></td></tr>
    11: ...ve on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
  20. 6w4c (3,791 bytes)
    2: ==Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5==
    3: ...on load='6w4c' size='340' side='right'caption='[[6w4c]], [[Resolution|resolution]] 1.75&Aring;' scene...
    5: .../b> use [https://proteopedia.org/fgij/fg.htm?mol=6W4C FirstGlance]. <br>
    8: ...ttps://prosat.h-its.org/prosat/prosatexe?pdbcode=6w4c ProSAT]</span></td></tr>
    11: ...ve on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.

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