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  1. Category:Cycloguanil (42 bytes)
    1: List of pages with the keyword Cycloguanil

Page text matches

  1. Malarial Dihydrofolate Reductase as Drug Target (10,680 bytes)
    2: ...arget the malarial DHFR include pyrimethamine and cycloguanil. Pyrimethamine is currently used in combination ...
    9: ... on biological substrates. For pyrimethamine and cycloguanil specifically, the S108N mutation greatly effects ...
    15: ...low bioavailbility.<ref name="yu"/> Wr99210, like cycloguanil, was significantly more basic than pyrimethamine,...
  2. 3irm (2,937 bytes)
    2: ...ate Reductase-Thymidylate Synthase COMPLEXED WITH Cycloguanil==
  3. 3irn (2,993 bytes)
    2: ...ase-Thymidylate Synthase COMPLEXED WITH NADPH AND Cycloguanil==
  4. 3qg2 (4,503 bytes)
    14: ...lassical antifolates such as pyrimethamine (PYR), cycloguanil, or trimethoprim are effective as selective inhib...
  5. 3qgt (4,356 bytes)
    14: ...lassical antifolates such as pyrimethamine (PYR), cycloguanil, or trimethoprim are effective as selective inhib...
  6. 6lh9 (4,147 bytes)
    14: A series of flexible diaminodihydrotriazines or cycloguanil (Cyc) analogues are developed and shown to inhibi...
  7. 6lhi (4,228 bytes)
    14: A series of flexible diaminodihydrotriazines or cycloguanil (Cyc) analogues are developed and shown to inhibi...
  8. 6lhj (4,220 bytes)
    14: A series of flexible diaminodihydrotriazines or cycloguanil (Cyc) analogues are developed and shown to inhibi...
  9. 4dpd (4,982 bytes)
    14: ...late antimalarial drugs such as pyrimethamine and cycloguanil, the clinical efficacy of which have been comprom...
  10. 4dph (5,155 bytes)
    14: ...late antimalarial drugs such as pyrimethamine and cycloguanil, the clinical efficacy of which have been comprom...
  11. 4dp3 (5,100 bytes)
    14: ...late antimalarial drugs such as pyrimethamine and cycloguanil, the clinical efficacy of which have been comprom...
  12. 3um5 (4,427 bytes)
    14: ... A16V and S108T specifically confer resistance to cycloguanil (CYC) but not to pyrimethamine (PYR). In order to...
    16: ...um Dihydrofolate Reductase Explains Resistance to Cycloguanil.,Vanichtanankul J, Taweechai S, Uttamapinant C, C...
  13. 3um6 (2,184 bytes)
    2: ...smodium falciparum DHFR-TS (T9/94) complexed with cycloguanil, NADPH and dUMP==
  14. 3um8 (2,135 bytes)
    2: ...type Plasmodium falciparum DHFR-TS complexed with cycloguanil and NADPH==
  15. 4ddr (5,770 bytes)
    16: ...late antimalarial drugs such as pyrimethamine and cycloguanil, the clinical efficacy of which have been comprom...
  16. 4kne (2,077 bytes)
    2: ...e from Mycobacterium tuberculosis in complex with cycloguanil==
  17. Category:Cycloguanil (42 bytes)
    1: List of pages with the keyword Cycloguanil
  18. 9dar (4,187 bytes)
    2: ...) in an occluded conformation and in complex with cycloguanil==
    14: ...he 2,4-diamino-1,6-dihydro-1,3,5-triazine (DADHT) cycloguanil scaffold to a variety of derivatives designed to ...
  19. 8rhx (4,218 bytes)
    12: ...ed on the amino dihydrotriazine motif of the drug Cycloguanil (Cyc), a known inhibitor of both folate enzymes, ...
    14: ...s Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Ag...
  20. 8rhy (4,165 bytes)
    12: ...ed on the amino dihydrotriazine motif of the drug Cycloguanil (Cyc), a known inhibitor of both folate enzymes, ...
    14: ...s Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Ag...

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