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  1. Image:Schema-defensins.jpg (0 bytes)

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  1. Defensin (1,441 bytes)
    5: ...e [[Plant defensin]]. '''Alpha-, beta- and theta-defensins''' are classified according to their invariant Cy...
    6: *'''alpha defensins''' are antibiotic peptides produced in the Paneth...
    7: *'''theta defensins''' are cyclic antibiotic peptides <ref>PMID:15544...
  2. 1dfn (3,253 bytes)
    10: ...against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing th...
    13: ...The dimeric assembly suggests mechanisms by which defensins might bind to and permeabilize the lipid bilayer.
  3. 1e4q (3,714 bytes)
    13: ... findings are of particular interest because beta-defensins have been suggested as lead compounds for the dev...
    15: Structure determination of human and murine beta-defensins reveals structural conservation in the absence of...
  4. 1fd3 (3,641 bytes)
    14: ...ed mechanism of membrane permeabilization by beta-defensins, rather than a mechanism based on formation of bi...
  5. 1fd4 (3,641 bytes)
    14: ...ed mechanism of membrane permeabilization by beta-defensins, rather than a mechanism based on formation of bi...
  6. 1fqq (3,252 bytes)
    13: ...eviously ascribed to solution structures of alpha-defensins or to the beta-defensin BNBD-12. This novel struc...
  7. 1iju (4,097 bytes)
    24: ...icrobial and chemotactic properties of human beta-defensins.
    26: ...: new insights into structural properties of beta-defensins.,Hoover DM, Chertov O, Lubkowski J J Biol Chem. 2...
  8. 1kj6 (4,588 bytes)
    23: ...-sheet. The surface charge density of each of the defensins is markedly different, with the surface of HBD3 s...
    25: The solution structures of the human beta-defensins lead to a better understanding of the potent bact...
  9. 1m8a (4,829 bytes)
    24: ...in-1 and -2. Molecules of MIP-3alpha and the beta-defensins seem to share few structural motifs that are like...
    26: ...ine receptor-6-binding activities with human beta-defensins.,Hoover DM, Boulegue C, Yang D, Oppenheim JJ, Tuc...
  10. 2lye (2,877 bytes)
    11: ...of action. The structural definition of the theta-defensins and the cyclic cystine ladder will help to guide ...
    13: ...ation of the Cyclic Cystine Ladder Motif of theta-Defensins.,Conibear AC, Rosengren KJ, Harvey PJ, Craik DJ B...
  11. 1zmh (4,521 bytes)
    11: ...against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing th...
    14: ... the Gly-Xaa-Cys motif conserved in all mammalian defensins.
    16: ...truction of the conserved beta-bulge in mammalian defensins using D-amino acids.,Xie C, Prahl A, Ericksen B, ...
  12. 1zmi (4,473 bytes)
    11: ...against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing th...
    14: ... the Gly-Xaa-Cys motif conserved in all mammalian defensins.
    16: ...truction of the conserved beta-bulge in mammalian defensins using D-amino acids.,Xie C, Prahl A, Ericksen B, ...
  13. 1zmk (4,471 bytes)
    11: ...against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing th...
    14: ... the Gly-Xaa-Cys motif conserved in all mammalian defensins.
    16: ...truction of the conserved beta-bulge in mammalian defensins using D-amino acids.,Xie C, Prahl A, Ericksen B, ...
  14. 1zmm (3,961 bytes)
    13: ...s highest bactericidal activity among human alpha-defensins.
    15: Crystal structures of human alpha-defensins HNP4, HD5, and HD6.,Szyk A, Wu Z, Tucker K, Yang ...
  15. 1zmp (4,253 bytes)
    11: ...against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing th...
    14: ...s highest bactericidal activity among human alpha-defensins.
    16: Crystal structures of human alpha-defensins HNP4, HD5, and HD6.,Szyk A, Wu Z, Tucker K, Yang ...
  16. 1zmq (4,003 bytes)
    14: ...s highest bactericidal activity among human alpha-defensins.
    16: Crystal structures of human alpha-defensins HNP4, HD5, and HD6.,Szyk A, Wu Z, Tucker K, Yang ...
  17. 2nlb (4,660 bytes)
    24: Defensins are small (30-45 amino acid residues) cationic pr...
  18. 2nlc (4,713 bytes)
    24: Defensins are small (30-45 amino acid residues) cationic pr...
  19. 2nld (4,714 bytes)
    24: Defensins are small (30-45 amino acid residues) cationic pr...
  20. 2nle (4,714 bytes)
    24: Defensins are small (30-45 amino acid residues) cationic pr...

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