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Article title matches
- Category:Fviia activation (47 bytes)
1: List of pages with the keyword Fviia activation - Category:Fviia and souluble tissue factor (63 bytes)
1: List of pages with the keyword Fviia and souluble tissue factor - Image:FVIIa-TF FX.jpg (36 bytes)
1: Complex of TF-FVIIa and FX substrate - FVIIa (25 bytes)
- Category:Fviia (36 bytes)
1: List of pages with the keyword Fviia - Image:Fviia.pdb (0 bytes)
Page text matches
- 2c4f (5,766 bytes)
26: ...hrombotic drugs. A fluoropyridine-based series of FVIIa/TF inhibitors was discovered which utilized a dii... - 4isi (4,814 bytes)
16: ..., S2 and S3 pockets. Compound 9b showed excellent FVIIa potency, good selectivity against FIXa, Xa, XIa a...
18: ...c pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.,Zhang X, Glunz PW, Jiang W, Schmitt A... - 1bf9 (5,983 bytes)
25: ...is responsible for the increased affinity of FVII/FVIIa for TF. - 1f7e (6,029 bytes)
25: ...ain, it may affect the interaction of full-length FVIIa with TF by influencing its Ca2+-binding affinity. - 1f7m (6,032 bytes)
25: ...ain, it may affect the interaction of full-length FVIIa with TF by influencing its Ca2+-binding affinity. - 1ff7 (6,224 bytes)
26: ...ain, it may affect the interaction of full-length FVIIa with TF by influencing its Ca2+-binding affinity. - 1ffm (6,227 bytes)
26: ...ain, it may affect the interaction of full-length FVIIa with TF by influencing its Ca2+-binding affinity. - 1jbu (6,611 bytes)
26: ...TF-mediated allosteric control of the activity of FVIIa can be rationalized. The reregistering beta stran... - 4ish (4,759 bytes)
16: ...model. A crystal structure of BMS-593214 bound to FVIIa highlights key contacts with Asp 189, Lys 192, an...
18: ...cale synthesis of BMS-593214, a potent, selective FVIIa inhibitor.,Priestley ES, De Lucca I, Zhou J, Zhou... - 1wqv (6,084 bytes)
26: ...ture-based drug design of specific inhibitors for FVIIa/TF. - 1wss (6,530 bytes)
26: ...ture-based drug design of specific inhibitors for FVIIa/TF. - 1wtg (6,448 bytes)
26: ...ortant role in achieving selective inhibition for FVIIa/TF. - 1wun (6,281 bytes)
26: ...d with Gln217, with a unique bent conformation in FVIIa/TF accompanied by conformational changes of the i... - 1wv7 (6,307 bytes)
26: ...d with Gln217, with a unique bent conformation in FVIIa/TF accompanied by conformational changes of the i... - 1ygc (6,745 bytes)
26: ...ure revealed a novel, nonstandard conformation of FVIIa active site in the region of the oxyanion hole, a... - 1zr0 (4,943 bytes)
24: ... electrostatic interactions are weak, whereas for FVIIa, hydrophobic interactions are missing, and electr... - 2a2q (7,040 bytes)
26: ...hole is unusual and has biologic implications for FVIIa macromolecular substrate specificity and catalysi... - 2aei (5,636 bytes)
26: ...X-ray crystal structure of a fluoropyridine-based FVIIa/TF inhibitor bound in the active site of the enzy... - 2aer (7,064 bytes)
26: ...hole is unusual and has biologic implications for FVIIa macromolecular substrate specificity and catalysi... - 2b7d (5,943 bytes)
26: ...y selective and potent factor VIIa-tissue factor (fVIIa.TF) complex inhibitors were generated through str...
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