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Article title matches
- Category:Hdac8 (36 bytes)
1: List of pages with the keyword Hdac8 - Image:HDAC8.pdb (0 bytes)
- Image:HDAC8 mechanism.png (15 bytes)
1: HDAC8 mechanism - Image:HDAC8 Mutations Final.png (0 bytes)
- Image:Hdac8 mechanism.PNG (32 bytes)
1: Figure 1. Deacetylation by HDAC8 - Histone deacetylase 8 (HDAC8) (16,489 bytes)
11: ...NA, increasing the potential for gene expression. HDAC8 reverses this reaction by catalyzing the removal ...
14: ...47 </ref> The structure reported here is of Human HDAC8, a 377 residue, Class I HDAC.
16: ...on comparing conservation of residues (143-182 in HDAC8) to homologous sequences in all class I HDACs. Ac...
18: ==HDAC8 Structure==
20: ...cent coumarin ring</scene> at its C terminus. The HDAC8 secondary structure consists of a <scene name='83... - Category:Complex schistosoma mansoni hdac8 inhibitor (76 bytes)
1: ...ages with the keyword Complex schistosoma mansoni hdac8 + inhibitor
Page text matches
- 1w22 (5,058 bytes)
2: ==Crystal structure of inhibited human HDAC8==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...design and development of selective inhibitors of HDAC8 as possible antitumor agents.
26: ...aryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor.,Vann... - 2v5x (4,917 bytes)
2: ==Crystal structure of HDAC8-inhibitor complex==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...irmed by activity and binding assays of wild-type HDAC8 and Asp101Ala, Tyr306Phe and Asp101Ala/Tyr306Phe ...
26: ...etylases as shown by the crystal structure of the HDAC8-substrate complex.,Vannini A, Volpari C, Gallinar... - 2v5w (4,898 bytes)
2: ==Crystal structure of HDAC8-substrate complex==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...irmed by activity and binding assays of wild-type HDAC8 and Asp101Ala, Tyr306Phe and Asp101Ala/Tyr306Phe ...
26: ...etylases as shown by the crystal structure of the HDAC8-substrate complex.,Vannini A, Volpari C, Gallinar... - 1t64 (5,015 bytes)
2: ==Crystal Structure of human HDAC8 complexed with Trichostatin A==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...lso suggests how phosphorylation of Ser39 affects HDAC8 activity.
26: Structural snapshots of human HDAC8 provide insights into the class I histone deacety... - 1t67 (5,002 bytes)
2: ==Crystal Structure of Human HDAC8 complexed with MS-344==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...lso suggests how phosphorylation of Ser39 affects HDAC8 activity.
26: Structural snapshots of human HDAC8 provide insights into the class I histone deacety... - 1t69 (4,932 bytes)
2: ==Crystal Structure of human HDAC8 complexed with SAHA==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...lso suggests how phosphorylation of Ser39 affects HDAC8 activity.
26: Structural snapshots of human HDAC8 provide insights into the class I histone deacety... - 1vkg (5,032 bytes)
2: ==Crystal Structure of Human HDAC8 complexed with CRA-19156==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...lso suggests how phosphorylation of Ser39 affects HDAC8 activity.
26: Structural snapshots of human HDAC8 provide insights into the class I histone deacety... - 7poz (3,784 bytes)
2: ==Crystal structure of Schistosoma mansoni HDAC8 with DMSO bound in the active site==
14: ...da classes, thus paving the way for the design of HDAC8-selective allosteric inhibitors with improved pro... - CH462 Butler (3,264 bytes)
61: ..._deacetylase_8_%28HDAC8%29 Histone deacetylase 8 (HDAC8)] - Category:Hdac8 (36 bytes)
1: List of pages with the keyword Hdac8 - 3ew8 (5,515 bytes)
2: ==Crystal Structure Analysis of human HDAC8 D101L variant==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3ewf (5,623 bytes)
2: ==Crystal Structure Analysis of human HDAC8 H143A variant complexed with substrate.==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3ezp (5,466 bytes)
2: ==Crystal Structure Analysis of human HDAC8 D101N variant==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3ezt (5,466 bytes)
2: ==Crystal Structure Analysis of Human HDAC8 D101E Variant==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3f06 (5,467 bytes)
2: ==Crystal Structure Analysis of Human HDAC8 D101A Variant.==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3f07 (5,456 bytes)
2: ==Crystal Structure Analysis of Human HDAC8 complexed with APHA in a new monoclinic crystal f...
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3f0r (5,408 bytes)
2: ==Crystal Structure Analysis of Human HDAC8 complexed with trichostatin A in a new monoclinic...
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ate binding site. Finally, the structure of H143A HDAC8 complexed with an intact acetylated tetrapeptide ... - 3mz3 (5,343 bytes)
2: ==Crystal structure of Co2+ HDAC8 complexed with M344==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
24: ...ations estimated in living cells, suggesting that HDAC8 could bind either or both Fe(2+) or Zn(2+) in viv... - 3mz4 (3,244 bytes)
2: ==Crystal structure of D101L Mn2+ HDAC8 complexed with M344==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin... - 3mz6 (3,185 bytes)
2: ==Crystal structure of D101L Fe2+ HDAC8 complexed with M344==
11: [https://www.uniprot.org/uniprot/HDAC8_HUMAN HDAC8_HUMAN] Responsible for the deacetylation of lysin...
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