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- Streptomyces griseus Aminopeptidase (SGAP) (9,198 bytes)
3: ...1xjo_cartoon.png |left| 200px | thumb | S griseus aminopeptidase, showing overall fold. Zinc ions are dark grey, ...
4: == ''Streptomyces griseus'' Aminopeptidase (SGAP) ==
7: ''S. griseus'' [[Aminopeptidase]] (SGAP; E.C. 3.4.11.-) cleaves the N-terminal am...
9: [[Image:aminopeptidase_rxn2.png | left | thumb| 500px | Reaction catalyz...
13: ...exopeptidase superfamily. It has a phosphorylase/hydrolase-like α/β fold, consisting of a 3-layer <scene n... - 1gw6 (5,084 bytes)
2: ==STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT==
11: ...proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:197549...
24: ...the enzyme's ability to generate LTB4 whereas the aminopeptidase activity is preserved. We propose that Asp-375, p...
26: Leukotriene A4 hydrolase: selective abrogation of leukotriene B4 formation...
33: *[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]] - 1a6r (4,138 bytes)
2: ==GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A==
11: ...tides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the tox...
24: ...ptidase on its C terminus to convert itself to an aminopeptidase and peptide ligase. The substrate specificity of ...
26: ...leomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.,Zheng W, Johnston SA, Joshua... - 1h19 (4,830 bytes)
2: ==STRUCTURE OF [E271Q]LEUKOTRIENE A4 HYDROLASE==
11: ...proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:197549...
24: ... pertains to all members of the M1 family of zinc aminopeptidases. Hence, Glu-271 is a unique example of an amino ...
26: Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specif...
33: *[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]] - 1vz8 (4,739 bytes)
24: ...ading frame) displays the same fold as an DmpA (L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi... - 1vz7 (4,660 bytes)
24: ...ading frame) displays the same fold as an DmpA (L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi... - 1vz6 (4,663 bytes)
24: ...ading frame) displays the same fold as an DmpA (L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi... - 3gcb (4,198 bytes)
2: ==GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454==
11: ...tides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the tox...
24: ...ptidase on its C terminus to convert itself to an aminopeptidase and peptide ligase. The substrate specificity of ...
26: ...leomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.,Zheng W, Johnston SA, Joshua... - 8twx (1,871 bytes)
2: ... Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity==
10: ...proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:197549... - 1hs6 (3,076 bytes)
2: ==STRUCTURE OF LEUKOTRIENE A4 HYDROLASE COMPLEXED WITH BESTATIN.==
11: ...proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:197549...
24: *[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]] - 1sqm (2,976 bytes)
2: ==STRUCTURE OF [R563A] LEUKOTRIENE A4 HYDROLASE==
11: ...proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:197549...
24: *[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]] - 7llq (4,272 bytes)
2: ...-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity==
11: ...proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.<ref>PMID:1897988</ref> <ref>PMID:197549...
14: ...minopeptidase activity (AP) of the leukotriene A4 hydrolase (LTA4H) enzyme has emerged as a therapeutic targe...
16: ...endent modulation of the leukotriene A4 hydrolase aminopeptidase activity and effect in a murine model of acute lu...
23: *[[Leukotriene A4 Hydrolase|Leukotriene A4 Hydrolase]] - Aminopeptidase (4,487 bytes)
1: ...'Journal:JBIC:15/Cv/1' caption='Bacterial leucine aminopeptidase complex with 8-hydroxyquinoline, glycerol, SCN, Z...
5: [[Aminopeptidase|Aminopeptidases]] (AP) ([[EC]] 3) are metal - mostly Zn-dependen...
9: ... griseus''. See details in [[Streptomyces griseus Aminopeptidase (SGAP)]].<br />
10: ... called '''aminopeptidase N'''. See details in [[Aminopeptidase N]].<br />
11: * '''Aminopeptidase C''' is a Phe aminopeptidase from ''Aspergillus niger''<ref>PMID:12571053</ref... - 1gcb (3,143 bytes)
2: ==GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL)==
11: ...tides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the tox... - 1mtz (4,268 bytes)
23: ... is a 33.5 kDa serine peptidase of the alpha/beta-hydrolase family from the archaeon Thermoplasma acidophilum...
25: Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic m... - 1mu0 (4,486 bytes)
24: ... is a 33.5 kDa serine peptidase of the alpha/beta-hydrolase family from the archaeon Thermoplasma acidophilum...
26: Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic m... - 1orw (6,081 bytes)
24: ...ng a Glu-Glu motif that distinguishes DP IV as an aminopeptidase and an oxyanion trap that binds and activates the... - 2dzy (4,720 bytes)
2: ...stal structure of N392A mutant of yeast bleomycin hydrolase==
10: ...tides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the tox...
23: Bleomycin hydrolase (BH) is a hexameric papain family cysteine protea...
25: ... residues of the papain family protease bleomycin hydrolase: new insights into active-site structure.,O'Farre... - 2dzz (4,720 bytes)
2: ...stal structure of N392V mutant of yeast bleomycin hydrolase==
10: ...tides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the tox...
23: Bleomycin hydrolase (BH) is a hexameric papain family cysteine protea...
25: ... residues of the papain family protease bleomycin hydrolase: new insights into active-site structure.,O'Farre... - 2e01 (4,720 bytes)
2: ...stal structure of H369A mutant of yeast bleomycin hydrolase==
10: ...tides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the tox...
23: Bleomycin hydrolase (BH) is a hexameric papain family cysteine protea...
25: ... residues of the papain family protease bleomycin hydrolase: new insights into active-site structure.,O'Farre...
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