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Article title matches
- Category:Il-4 stat (40 bytes)
1: List of pages with the keyword Il-4 stat - Category:Protein inhibitor of activated stat (66 bytes)
1: ...s with the keyword Protein inhibitor of activated stat - Category:Stat (35 bytes)
1: List of pages with the keyword Stat - Category:Jak/stat (39 bytes)
1: List of pages with the keyword Jak/stat - Category:Stat n-terminal domain (53 bytes)
1: List of pages with the keyword Stat n-terminal domain - Category:Jak-stat (39 bytes)
1: List of pages with the keyword Jak-stat - Category:Jak-stat pathway (47 bytes)
1: List of pages with the keyword Jak-stat pathway - JAK-STAT signaling pathway (2,630 bytes)
1: ...350' side='right' scene='54/543313/Cv/1' caption='JAK2 kinase domain complex with inhibitor thienopyrid...
2: ...ansducer and activator of transcription proteins (STATs), and receptors (which bind the chemical signals...
5: ...JAK3''' is predominantly active in immune cells. JAK3 is activated by cytokines whose receptors contai...
7: Jak3 inhibitors are tested in treatment of autoimmune...
9: ...lofibrosis<ref>PMID:19393837</ref>. Mutations in Jak3 are associated with immune deficiency.
Page text matches
- 9big (3,481 bytes)
2: ==Stat6 bound to degrader AK-1690==
11: [https://www.uniprot.org/uniprot/STAT6_HUMAN STAT6_HUMAN] Carries out a dual function: signal trans...
14: ...erful tool with which to investigate the roles of STAT6 in human diseases and biological processes and a...
16: ...scovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader.,Kaneshige A, Yang Y, Bai L, Wan... - 1hkx (5,350 bytes)
11: ...n-beta (IFN-beta) stimulation, stimulates the JAK-STAT signaling pathway (By similarity). Acts as a nega... - 1uzg (6,618 bytes)
11: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway (By similarity). - 1oke (6,077 bytes)
10: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway (By similarity). - 1ok8 (6,644 bytes)
5: ... The July 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month...
11: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway (By similarity).
14: ...ble E ectodomain (sE) in its trimeric, postfusion state reveals striking differences from the dimeric, p... - 8ewy (4,114 bytes)
2: ==Structure of Janus Kinase (JAK) dimer complexed with cytokine receptor intracell...
11: ...AT signaling through the transactivation of other JAK kinases associated with signaling receptors.[UniP...
14: ...tep of JAK signaling and allosteric mechanisms of JAK inhibition. - 1oan (6,094 bytes)
11: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway (By similarity). - 2ux0 (6,542 bytes)
13: ...zes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).[UniProtKB:Q923...
26: ...heir tetradecameric and physiological dodecameric states. All four autoinhibited human CaMKIIs were mono... - 2j7w (10,500 bytes)
5: ... The July 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month...
11: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway.[UniProtKB:P17763] - 2j7u (10,253 bytes)
11: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway.[UniProtKB:P17763] - 2v7o (6,656 bytes)
13: ...zes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).[UniProtKB:Q923...
26: ...heir tetradecameric and physiological dodecameric states. All four autoinhibited human CaMKIIs were mono... - 1bf5 (7,310 bytes)
2: ==TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX==
11: ... the genus Candida, mainly Candida albicans. Note=STAT1 mutations in patients with autosomal dominant ca...
13: ...f the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and ...
26: ...FkappaB and the p53 tumor suppressor protein. The STAT-1 dimer forms a contiguous C-shaped clamp around ...
28: Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.,Chen X, Vinkemeier U, Zhao ... - 1cmo (6,400 bytes)
25: ... binding domains of NF-kappaB, NFAT1, p53 and the STAT proteins. NMR spectroscopy of a 43.6 kD RD-beta-D... - 1co1 (6,304 bytes)
25: ... the DNA-binding domains of NF-kappaB, NFAT, p53, STAT-1, and the T-domain. Thus, these proteins form a ... - 4hvs (6,907 bytes)
13: ...he transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (... - 1exz (5,345 bytes)
13: ...ctivation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, ... - 1f42 (6,433 bytes)
13: ... composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than ... - 1f45 (6,342 bytes)
13: ... composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than ... - 9fk0 (9,219 bytes)
11: ...phorylation, thereby preventing activation of JAK-STAT signaling pathway (PubMed:16188985).[UniProtKB:P1... - 1igr (8,140 bytes)
13: ...l for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be r...
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