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Article title matches

  1. Category:Keap1 (36 bytes)
    1: List of pages with the keyword Keap1
  2. Category:Keap1 kelch domain (49 bytes)
    1: List of pages with the keyword Keap1 kelch domain
  3. Category:Keap1-nrf2 system (48 bytes)
    1: List of pages with the keyword Keap1-nrf2 system
  4. Image:Keap1.pdb (0 bytes)
  5. Image:CUL3 N-terminal domain bound to KEAP1.pdb (0 bytes)
  6. Image:Inputs and outputs of KEAP1 NRF2 pathway.jpg (62 bytes)

Page text matches

  1. 9cga (6,225 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=4Y8:1-HYDROXYPROPAN-2-ONE'>4Y8</scene></td>...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cga ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: <div class="pdbe-citations 9cga" style="background-color:#fffaf0;...
  2. 9cgb (6,225 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=4Y8:1-HYDROXYPROPAN-2-ONE'>4Y8</scene></td>...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cgb ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: <div class="pdbe-citations 9cgb" style="background-color:#fffaf0;...
  3. 9cgd (6,280 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1A7V:(2~{R})-2-azanyl-3-[(2~{S})-2-oxidany...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cgd ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: <div class="pdbe-citations 9cgd" style="background-color:#fffaf0;...
  4. 9cge (6,246 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1A7V:S-[(2S)-2-hydroxypropanoyl]-L-cystein...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cge ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: <div class="pdbe-citations 9cge" style="background-color:#fffaf0;...
  5. 9cgf (6,226 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=4Y8:1-HYDROXYPROPAN-2-ONE'>4Y8</scene></td>...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cgf ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: <div class="pdbe-citations 9cgf" style="background-color:#fffaf0;...
  6. 9cgg (6,280 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1A7V:(2~{R})-2-azanyl-3-[(2~{S})-2-oxidany...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cgg ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: <div class="pdbe-citations 9cgg" style="background-color:#fffaf0;...
  7. 9f2p (4,238 bytes)
    2: ==Crystal structure of Keap1 kelch domain in complex with a fluorenone-based s...
    7: ...DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9f2p ProSAT]</span></td></tr>
    11: [https://www.uniprot.org/uniprot/KEAP1_MOUSE KEAP1_MOUSE] Retains NFE2L2/NRF2 in the cytosol. Functi...
    14: ...cation in the design of potent and more drug-like Keap1-Nrf2 inhibitors.
  8. 9f2q (4,314 bytes)
    2: ==Crystal structure of Keap1 kelch domain in complex with a tetrahydroisoquino...
    7: ...DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9f2q ProSAT]</span></td></tr>
    11: [https://www.uniprot.org/uniprot/KEAP1_MOUSE KEAP1_MOUSE] Retains NFE2L2/NRF2 in the cytosol. Functi...
    14: ...cation in the design of potent and more drug-like Keap1-Nrf2 inhibitors.
  9. 9veq (285 bytes)
    7: Description: Crystal structure of Keap1 in complex with a small molecule inhibitor, KMN00...
  10. 4iqk (3,216 bytes)
    2: ==Crystal structure of cpd 16 bound to Keap1 Kelch domain==
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=IQK:N,N-NAPHTHALENE-1,4-DIYLBIS(4-METHOXYBE...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iqk ProSAT]</span></td></tr>
    11: [https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
    14: ... molecule compounds that specifically bind to the Keap1 Kelch-DC domain as measured by NMR, native mass s...
  11. 9etx (3,458 bytes)
    2: ==KEAP1 BTB in complex with compound 23==
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H67:(3~{R})-4-[4-(2-chlorophenyl)sulfonyl...
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9etx ProSAT]</span></td></tr>
    11: [https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
    14: ...el of kinases. The nature of its interaction with KEAP1 and the origin of its selectivity were revealed b...
  12. 9ety (3,598 bytes)
    2: ==KEAP1 in complex with compound 25==
    7: ...and=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ety ProSAT]</span></td></tr>
    11: [https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
    14: ...el of kinases. The nature of its interaction with KEAP1 and the origin of its selectivity were revealed b...
  13. 1j42 (5,920 bytes)
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j42 ProSAT]</span></td></tr>
    12: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    21: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j42 ConSurf].
    31: <div class="pdbe-citations 1j42" style="background-color:#fffaf0;...
  14. 4ifj (1,878 bytes)
    2: ...ystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes==
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ifj ProSAT]</span></td></tr>
    10: [https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
  15. 1p5f (4,788 bytes)
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p5f ProSAT]</span></td></tr>
    12: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    21: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p5f ConSurf].
  16. 1pdv (6,233 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdv ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pdv ConSurf].
    32: <div class="pdbe-citations 1pdv" style="background-color:#fffaf0;...
  17. 1pdw (6,233 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdw ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pdw ConSurf].
    32: <div class="pdbe-citations 1pdw" style="background-color:#fffaf0;...
  18. 1pe0 (4,734 bytes)
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pe0 ProSAT]</span></td></tr>
    12: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    21: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pe0 ConSurf].
  19. 1q2u (4,982 bytes)
    5: ...PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ps4 1ps4]. Full crystallographic inform...
    7: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q2u ProSAT]</span></td></tr>
    12: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    21: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q2u ConSurf].
  20. 1soa (6,702 bytes)
    7: ...<td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
    8: ...Bsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1soa ProSAT]</span></td></tr>
    13: ...bilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7...
    22: ...://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1soa ConSurf].
    32: <div class="pdbe-citations 1soa" style="background-color:#fffaf0;...

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