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Article title matches

  1. Category:Pyruvate kinase in the active r-state (68 bytes)
    1: ... of pages with the keyword Pyruvate kinase in the active r-state
  2. Category:Kinase inhibitor active site folded activation loop uba domain (93 bytes)
    1: List of pages with the keyword Kinase inhibitor active site folded activation loop uba domain

Page text matches

  1. 2src (9,009 bytes)
    2: ==CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP==
    5: ... Molecule of the Month] feature on ''Src Tyrosine Kinase'' by David S. Goodsell is [https://dx.doi.org/10...
    11: ...uniprot.org/uniprot/SRC_HUMAN SRC_HUMAN] Note=SRC kinase activity has been shown to be increased in severa...
    13: ...ivation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that ...
    26: ... that stabilizes the inactive conformation of the kinase domain, blocks the peptide substrate-binding site...
  2. 1e4v (4,128 bytes)
    2: ==Mutant G10V of adenylate kinase from E. coli, modified in the Gly-loop==
    24: ...ase these mutations cause smallish changes at the active site. Relating the structural changes to the know...
    26: Crystal structures of two mutants of adenylate kinase from Escherichia coli that modify the Gly-loop.,M...
    33: *[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
  3. 1e4y (4,127 bytes)
    2: ==Mutant P9L of adenylate kinase from E. coli, modified in the Gly-loop==
    24: ...ase these mutations cause smallish changes at the active site. Relating the structural changes to the know...
    26: Crystal structures of two mutants of adenylate kinase from Escherichia coli that modify the Gly-loop.,M...
    33: *[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
  4. 1vyw (7,803 bytes)
    11: ...orylation is low in S phase when recombination is active, but increases as cells progress towards mitosis....
    24: .../cyclin A and CDK2/cyclin E, and inhibiting their kinase activity are regarded as promising antitumor agen...
    34: ...n-dependent kinase 3D structures|Cyclin-dependent kinase 3D structures]]
  5. 1vyz (7,690 bytes)
    11: ...orylation is low in S phase when recombination is active, but increases as cells progress towards mitosis....
    24: .../cyclin A and CDK2/cyclin E, and inhibiting their kinase activity are regarded as promising antitumor agen...
    33: ...n-dependent kinase 3D structures|Cyclin-dependent kinase 3D structures]]
  6. 2bon (3,877 bytes)
    2: ==Structure of an Escherichia coli lipid kinase (YegS)==
    24: ...site composed of residues conserved in most lipid kinases.
    26: ...YegS, a homologue to the mammalian diacylglycerol kinases, reveals a novel regulatory metal binding site.,...
  7. 2cni (5,849 bytes)
    11: ...ylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important r...
    24: ...es of the protein-tyrosine phosphatase 1B (PTP1B) active site and inhibitor complexes have aided in optimi...
  8. 2cn5 (7,986 bytes)
    13: ...te inhibition by MDM2, leading to accumulation of active p53/TP53. Phosphorylation of MDM4 may also reduce...
    26: ... data suggest that this dimer is the biologically active state promoted by ATM-phosphorylation, and also s...
    28: ...s-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange.,Oliver AW, Paul A, Boxal...
    35: ...ein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
  9. 2cnh (5,858 bytes)
    11: ...ylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important r...
    24: ...es of the protein-tyrosine phosphatase 1B (PTP1B) active site and inhibitor complexes have aided in optimi...
  10. 2cn8 (7,949 bytes)
    13: ...te inhibition by MDM2, leading to accumulation of active p53/TP53. Phosphorylation of MDM4 may also reduce...
    26: ... data suggest that this dimer is the biologically active state promoted by ATM-phosphorylation, and also s...
    28: ...s-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange.,Oliver AW, Paul A, Boxal...
    35: ...ein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
  11. 2cng (5,901 bytes)
    11: ...ylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important r...
    24: ...es of the protein-tyrosine phosphatase 1B (PTP1B) active site and inhibitor complexes have aided in optimi...
  12. 2cne (5,882 bytes)
    11: ...ylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important r...
    24: ...es of the protein-tyrosine phosphatase 1B (PTP1B) active site and inhibitor complexes have aided in optimi...
  13. 2cnf (5,828 bytes)
    11: ...ylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important r...
    24: ...es of the protein-tyrosine phosphatase 1B (PTP1B) active site and inhibitor complexes have aided in optimi...
  14. 1wcc (6,954 bytes)
    11: ...orylation is low in S phase when recombination is active, but increases as cells progress towards mitosis....
    24: ...w lead compounds have been identified for p38 MAP kinase starting from fragments such as those described i...
    33: ...n-dependent kinase 3D structures|Cyclin-dependent kinase 3D structures]]
  15. 1wch (4,972 bytes)
    24: ...n, which changes Met-2307 to Thr, is close to the active site cysteine and decreases activity significantl...
  16. 1qr5 (6,407 bytes)
    10: ...erase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of...
    23: ...uld represent some kind of anchoring point of the active center loop that holds it in the right place in s...
  17. 2jat (4,534 bytes)
    2: ==Structure of deoxyadenosine kinase from M.mycoides with products dcmp and a flexible...
    24: ...ew amino acid alterations in the proximity of the active site. To investigate the substrate specificity, M...
    26: ...e-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity.,Weli...
  18. 2jaq (4,394 bytes)
    2: ==Structure of deoxyadenosine kinase from M. mycoides with bound dCTP==
    24: ...ew amino acid alterations in the proximity of the active site. To investigate the substrate specificity, M...
    26: ...e-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity.,Weli...
  19. 2jas (4,447 bytes)
    2: ==Structure of deoxyadenosine kinase from M.mycoides with bound dATP==
    24: ...ew amino acid alterations in the proximity of the active site. To investigate the substrate specificity, M...
    26: ...e-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity.,Weli...
  20. 2ja1 (4,859 bytes)
    2: ==Thymidine kinase from B. cereus with TTP bound as phosphate donor....
    24: ...conformation is closed and thymidine occupies the active site. Another conformational difference lies with...
    26: Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus prov...
    33: *[[Thymidine kinase 3D structures|Thymidine kinase 3D structures]]

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