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  1. 2o2k (5,833 bytes)
    2: ...ture of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N==
    10: ...in MS activity could be associated with mild hyperhomocysteinemia, a risk factor for cardiovascular disease and ...
    12: ...ne. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
    25: ...raction is enhanced in the presence of S-adenosyl-methionine. Binding of the D963E/K1071N mutant activation do...
    27: ...tion of the activation domain of human methionine synthase.,Wolthers KR, Toogood HS, Jowitt TA, Marshall KR,...
  2. 1k7y (4,371 bytes)
    11: ...ne. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    24: ...omocysteine, methyltetrahydrofolate and S-adenosylmethionine (AdoMet). Here we describe the 3.0 A structure of...
    26: ...n alternation switches B(12)-dependent methionine synthase to the activation conformation.,Bandarian V, Patt...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  3. 1k98 (4,373 bytes)
    11: ...ne. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    24: ...omocysteine, methyltetrahydrofolate and S-adenosylmethionine (AdoMet). Here we describe the 3.0 A structure of...
    26: ...n alternation switches B(12)-dependent methionine synthase to the activation conformation.,Bandarian V, Patt...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  4. 1msk (2,749 bytes)
    2: ==METHIONINE SYNTHASE (ACTIVATION DOMAIN)==
    7: ...ACT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
    11: ...ne. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    24: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  5. 1t7l (5,028 bytes)
    2: ...tal Structure of Cobalamin-Independent Methionine Synthase from T. maritima==
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
    24: ...)Zn site in the related enzymes, MetH and betaine-homocysteine methyltransferase, by its position in the barrel ...
    26: Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  6. 1u1h (4,830 bytes)
    2: ==A. thaliana cobalamine independent methionine synthase==
    7: ...NE'>MET</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+...
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation.<ref>PMID:15024005</ref>
    24: ...hydrofolate (CH3-H2PteGlun) to the sulfur atom of homocysteine (Hcy). We report here the first crystal structure...
    26: ...e synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.,Ferrer JL, Ravanel S, Robert M, Dumas R J Biol C...
  7. 1u1j (4,908 bytes)
    2: ==A. thaliana cobalamine independent methionine synthase==
    7: ...NE'>MET</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+...
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation.<ref>PMID:15024005</ref>
    24: ...hydrofolate (CH3-H2PteGlun) to the sulfur atom of homocysteine (Hcy). We report here the first crystal structure...
    26: ...e synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.,Ferrer JL, Ravanel S, Robert M, Dumas R J Biol C...
  8. 1u1u (4,778 bytes)
    2: ==A. thaliana cobalamine independent methionine synthase==
    7: ..." id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+...
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation.<ref>PMID:15024005</ref>
    24: ...hydrofolate (CH3-H2PteGlun) to the sulfur atom of homocysteine (Hcy). We report here the first crystal structure...
    26: ...e synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.,Ferrer JL, Ravanel S, Robert M, Dumas R J Biol C...
  9. 1u22 (4,922 bytes)
    2: ==A. thaliana cobalamine independent methionine synthase==
    7: ...ID'>HCS</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+...
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation.<ref>PMID:15024005</ref>
    24: ...hydrofolate (CH3-H2PteGlun) to the sulfur atom of homocysteine (Hcy). We report here the first crystal structure...
    26: ...e synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.,Ferrer JL, Ravanel S, Robert M, Dumas R J Biol C...
  10. 1xdj (2,879 bytes)
    2: ...ndent Methionine Synthase complexed with Zn2+ and Homocysteine==
    7: ...OL'>MRY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+...
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
    24: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  11. 1xpg (5,258 bytes)
    2: ...ndent Methionine Synthase complexed with Zn2+ and Methyltetrahydrofolate==
    7: ...OL'>MRY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+...
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
    24: ...)Zn site in the related enzymes, MetH and betaine-homocysteine methyltransferase, by its position in the barrel ...
    26: Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved...
  12. 1xr2 (5,152 bytes)
    2: ...in-Independent Methionine Synthase complexed with Methyltetrahydrofolate==
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
    24: ...)Zn site in the related enzymes, MetH and betaine-homocysteine methyltransferase, by its position in the barrel ...
    26: Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  13. 1q7m (4,246 bytes)
    2: ==Cobalamin-dependent methionine synthase (MetH) from Thermotoga maritima (Oxidized, Monocl...
    23: ...n to the folate (Fol) domain for remethylation by methyltetrahydrofolate (CH(3)-H(4)folate). Here, we describe crystal str...
    25: ...rge domain motions during catalysis by methionine synthase.,Evans JC, Huddler DP, Hilgers MT, Romanchuk G, M...
    32: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  14. 1q7q (4,241 bytes)
    2: ==Cobalamin-dependent methionine synthase (1-566) from T. maritima (Oxidized, Orthorhombic)...
    23: ...n to the folate (Fol) domain for remethylation by methyltetrahydrofolate (CH(3)-H(4)folate). Here, we describe crystal str...
    25: ...rge domain motions during catalysis by methionine synthase.,Evans JC, Huddler DP, Hilgers MT, Romanchuk G, M...
    32: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  15. 1q85 (4,469 bytes)
    2: ==Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima (Cd2+ complex, S...
    7: ...ION'>CD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
    24: ...n to the folate (Fol) domain for remethylation by methyltetrahydrofolate (CH(3)-H(4)folate). Here, we describe crystal str...
    26: ...rge domain motions during catalysis by methionine synthase.,Evans JC, Huddler DP, Hilgers MT, Romanchuk G, M...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  16. 1q8a (4,550 bytes)
    2: ==Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima (Cd2+:L-Hcy comp...
    7: ...ID'>HCS</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
    24: ...n to the folate (Fol) domain for remethylation by methyltetrahydrofolate (CH(3)-H(4)folate). Here, we describe crystal str...
    26: ...rge domain motions during catalysis by methionine synthase.,Evans JC, Huddler DP, Hilgers MT, Romanchuk G, M...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  17. 3bq5 (2,801 bytes)
    2: ...ndent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic)==
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
    24: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  18. 3bq6 (4,547 bytes)
    2: ...e of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ (Monoclinic)==
    11: ...thyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
    24: ...hyltetrahydrofolate to homocysteine (Hcy) to form methionine, they display markedly different catalytic strate...
    26: ...inked to activation of homocysteine in methionine synthases.,Koutmos M, Pejchal R, Bomer TM, Matthews RG, Sm...
    33: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  19. 3bul (4,490 bytes)
    10: ...ne. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    23: ...ysteine, methyltetrahydrofolate, and S-adenosyl-l-methionine (AdoMet). These same rearrangements appear to pre...
    25: A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine liga...
    32: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
  20. 3iv9 (4,607 bytes)
    2: ==Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half in a "His-On" conformation=...
    10: ...ne. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    23: ...(s-s)MetH(CT) with cob(II)alamin and S-adenosyl-L-homocysteine represents the enzyme in the reactivation step pr...
    25: ...he reactivation of cobalamin-dependent methionine synthase.,Koutmos M, Datta S, Pattridge KA, Smith JL, Matt...
    32: *[[Methionine synthase 3D structures|Methionine synthase 3D structures]]

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