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Article title matches

  1. Category:Nbs1 (35 bytes)
    1: List of pages with the keyword Nbs1
  2. Category:Nbs1 in eukaryote (48 bytes)
    1: List of pages with the keyword Nbs1 in eukaryote

Page text matches

  1. 9bi4 (4,805 bytes)
    14: ...tifiable orthologs in all clades of life, whereas Nbs1/Xrs2 are present only in eukaryotes. In eukaryote...
  2. DNA repair protein 3D structures (6,779 bytes)
    74: **[[4fbw]] – fyRad32 + NBS1<br />
  3. 1l8d (4,667 bytes)
    24: The Mre11 complex (Mre11 Rad50 Nbs1) is central to chromosomal maintenance and functi...
  4. 1s8e (4,350 bytes)
    24: ...tein has wild-type ability to bind DNA, Rad50 and Nbs1; however, nuclease activity was completely abroga...
  5. 1us8 (5,062 bytes)
    23: ... mutant protein did form a complex with Mre11 and Nbs1, but was specifically deficient in all ATP-depend...
  6. 9q9h (4,715 bytes)
    16: ...atory RAD50 S site, necessitating a switch in the NBS1 C helix for ATM activation. At telomeric DNA, TRF...
    18: ... basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.,Fan ...
  7. 9q9i (5,547 bytes)
    2: ==Cryo-EM structure of human Mre11-Rad50-Nbs1 complex bound to DNA==
    13: ...s involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transduce...
    16: ...atory RAD50 S site, necessitating a switch in the NBS1 C helix for ATM activation. At telomeric DNA, TRF...
    18: ... basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.,Fan ...
  8. 9q9j (5,070 bytes)
    2: ==Cryo-EM structure of human Mre11-Rad50-Nbs1 (MRN) complex bound to DNA and telomeric factor T...
    14: ...atory RAD50 S site, necessitating a switch in the NBS1 C helix for ATM activation. At telomeric DNA, TRF...
    16: ... basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.,Fan ...
  9. 9q9k (4,765 bytes)
    16: ...atory RAD50 S site, necessitating a switch in the NBS1 C helix for ATM activation. At telomeric DNA, TRF...
    18: ... basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.,Fan ...
  10. 9q9m (5,051 bytes)
    2: ==Cryo-EM structure of human Mre11-Rad50-Nbs1 (MRN) complex bound to DNA and telomeric factor T...
    14: ...atory RAD50 S site, necessitating a switch in the NBS1 C helix for ATM activation. At telomeric DNA, TRF...
    16: ... basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.,Fan ...
  11. 2k2w (3,985 bytes)
    2: ==Second BRCT domain of NBS1==
    23: ...ites, most likely through a direct interaction of Nbs1 tandem BRCT domains with phosphorylated MDC1.
    25: ...its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.,Xu C, Wu L, Cui G, Botuyan M...
  12. 3dsc (4,144 bytes)
    23: ...forms the core of the multifunctional Mre11-Rad50-Nbs1 (MRN) complex that detects DNA double-strand brea...
  13. 3dsd (4,314 bytes)
    24: ...forms the core of the multifunctional Mre11-Rad50-Nbs1 (MRN) complex that detects DNA double-strand brea...
  14. 2wd5 (4,850 bytes)
    10: ...R. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase chec...
  15. 3hue (4,301 bytes)
    2: ==Structure of the S. pombe Nbs1 FHA-BRCT1-BRCT2 domains==
    11: [https://www.uniprot.org/uniprot/NBS1_SCHPO NBS1_SCHPO] Required for DNA damage repair and S-phase...
    24: ...ndrome mutations. Tethering of Ctp1 to a flexible Nbs1 arm suggests a mechanism for restricting DNA end ...
    26: Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordina...
  16. 3huf (4,403 bytes)
    2: ==Structure of the S. pombe Nbs1-Ctp1 complex==
    11: [https://www.uniprot.org/uniprot/NBS1_SCHPO NBS1_SCHPO] Required for DNA damage repair and S-phase...
    24: ...ndrome mutations. Tethering of Ctp1 to a flexible Nbs1 arm suggests a mechanism for restricting DNA end ...
    26: Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordina...
  17. 3i0m (4,353 bytes)
    2: ==Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain==
    11: [https://www.uniprot.org/uniprot/NBS1_SCHPO NBS1_SCHPO] Required for DNA damage repair and S-phase...
    24: ...ructural and functional interdependence underpins Nbs1 adaptor functions in the DNA-damage response.
    26: ...upramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.,Lloyd...
  18. 3i0n (4,354 bytes)
    2: ==Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain==
    11: [https://www.uniprot.org/uniprot/NBS1_SCHPO NBS1_SCHPO] Required for DNA damage repair and S-phase...
    24: ...ructural and functional interdependence underpins Nbs1 adaptor functions in the DNA-damage response.
    26: ...upramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.,Lloyd...
  19. Category:Nbs1 (35 bytes)
    1: List of pages with the keyword Nbs1
  20. 3t1i (3,225 bytes)
    12: ...morigenic mutations are primarily associated with Nbs1 binding and partly with nuclease activities, prov...

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