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Article title matches
- Category:Nek7 (35 bytes)
1: List of pages with the keyword Nek7
Page text matches
- 9h59 (3,674 bytes)
2: ...tructure of DDB1-CRBN in complex with NK7-902 and NEK7== - 3zke (4,559 bytes)
13: ...NIMA-family protein kinases Nek9/Nercc1, Nek6 and Nek7 constitute a signaling module activated in early ... - 3zkf (4,736 bytes)
14: ...NIMA-family protein kinases Nek9/Nercc1, Nek6 and Nek7 constitute a signaling module activated in early ... - 9nfq (3,954 bytes)
2: ...ructure of CRBN-DDB1 and MRT-3486 in complex with NEK7== - 2wqm (4,334 bytes)
2: ==Structure of apo human Nek7==
11: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro...
24: ...e constitutively active. The activity of Nek6 and Nek7, but not the tyrosine mutant, is increased by int...
26: ...bitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.,Richa... - 2wqn (4,458 bytes)
2: ==Structure of ADP-bound human Nek7==
11: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro...
24: ...e constitutively active. The activity of Nek6 and Nek7, but not the tyrosine mutant, is increased by int...
26: ...bitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.,Richa... - 2wqo (5,436 bytes)
24: ...e constitutively active. The activity of Nek6 and Nek7, but not the tyrosine mutant, is increased by int...
26: ...bitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.,Richa... - Pyrin domain (2,125 bytes)
18: [[6npy]] - hPYD in NLRP3 + NEK7 - Cryo EM<br /> - 9hne (4,215 bytes)
14: ...fied additional CRBN substrates, including GSPT1, NEK7, and CK1alpha, whose degradation potently induced...
16: Targeted degradation of GSPT1 and NEK7 by a molecular glue prodrug for treatment of HCC.... - 8sxn (2,388 bytes)
2: ==Structure of NLRP3 and NEK7 complex==
11: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro... - 4z7g (3,849 bytes)
14: ...hat found in the unrelated Ser/Thr protein kinase Nek7. We have developed a compound that potently inhib... - 4z7h (4,001 bytes)
14: ...hat found in the unrelated Ser/Thr protein kinase Nek7. We have developed a compound that potently inhib... - 5de2 (3,507 bytes)
2: ==Structural mechanism of Nek7 activation by Nek9-induced dimerisation==
10: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro...
13: ...97. Hence, we propose that the Nek9-CTD activates Nek7 through promoting back-to-back dimerization that ...
15: Mechanistic basis of Nek7 activation through Nek9 binding and induced dimer... - 8ujz (306 bytes)
7: Description: NLRP3/NEK7 bound to the inhibitor NIC-12 - 8ws0 (1,811 bytes)
2: ==Crystal structure of human NEK7 S195D mutant==
10: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro... - 8ws1 (1,983 bytes)
2: ==Crystal structure of human NEK7 D161N mutant==
11: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro... - 6i2i (4,090 bytes)
13: ...er, these data support a model in which NEK6- and NEK7-dependent phosphorylation promotes the dissociati...
15: Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promo... - 6npy (5,362 bytes)
2: ==Cryo-EM structure of NLRP3 bound to NEK7==
16: ... or NLRP3-knockout cells. These data suggest that NEK7 bridges adjacent NLRP3 subunits with bipartite in...
18: Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.,Sharif... - 6s73 (4,483 bytes)
2: ==Crystal structure of Nek7 SRS mutant bound to compound 51==
11: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro...
14: ...gh the SRS mutations are not required to obtain a Nek7-inhibitor structure, we conclude that it is a use...
16: Nek7 conformational flexibility and inhibitor binding ... - 6s75 (4,309 bytes)
2: ==Crystal structure of Nek7 bound to compound 51==
11: [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important ro...
14: ...gh the SRS mutations are not required to obtain a Nek7-inhibitor structure, we conclude that it is a use...
16: Nek7 conformational flexibility and inhibitor binding ...
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