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- Journal:Neuropharmacology:1 (3,077 bytes)
1: ...ad='' size='450' side='right' scene='85/857115/Cv/1' caption=''>
3: ...k Masson</big> <ref>doi 10.1016/j.neuropharm.2020.108236</ref>
10: <scene name='85/857115/Cv/13'>X-ray structures of Torpedo californica AChE i...
11: *Apo-state AChEs ([[1ea5]], [[1qid]], [[1w75]], [[2j3d]], [[2va9]]) are colored in pink.
12: ...ID [[1gpn]]; (-)-huperzine A /''Tc''AChE PDB ID [[1vot]]. - Journal:Neuropharmacology:2 (7,606 bytes)
1: ...ad='' size='450' side='right' scene='85/857780/Cv/1' caption=''>
3: ...Sussman and Israel Silman</big> <ref>pmid: 32795461</ref>
8: ...Fuxreiter, 2015<ref name="Fuxreiter">DOI:10.1201/b17979</ref>). In the following, after briefly surve...
10: ...rminus in a spectrum going from blue to red. The 51 amino acids that were mutated on the basis of the...
12: ...ns in blue. The OP moiety covalently attached to S198 in the mutant is displayed as balls, with the p...
Page text matches
- 1p4f (6,548 bytes)
3: ...ight'caption='[[1p4f]], [[Resolution|resolution]] 1.90Å' scene=''>
5: ...</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P4F FirstGlance]. <br>
6: ...ay diffraction, [[Resolution|Resolution]] 1.9Å</td></tr>
8: ...https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p4f ProSAT]</span></td></tr>
11: ...095</ref> <ref>PMID:21497122</ref> <ref>PMID:21408167</ref> - 2qs1 (4,598 bytes)
2: ...gand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution==
3: ...ight'caption='[[2qs1]], [[Resolution|resolution]] 1.80Å' scene=''>
5: ...> use [https://proteopedia.org/fgij/fg.htm?mol=2QS1 FirstGlance]. <br>
6: ...ay diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>
7: ...METHYL)-4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC+ACID'>UB1</scene></td></tr> - 2qs2 (4,585 bytes)
2: ...gand binding core dimer in complex with UBP318 at 1.80 Angstroms resolution==
3: ...ight'caption='[[2qs2]], [[Resolution|resolution]] 1.80Å' scene=''>
6: ...ay diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>
7: ...BOXYETHYL]-5-BROMO-2,6-DIOXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL}METHYL)THIOPHENE-2-CARBOXYLIC+ACID'>UBF</s...
11: ...ion from the retina to the hypothalamus.<ref>PMID:16540562</ref> - 2qs3 (5,633 bytes)
2: ...gand binding core dimer in complex with UBP316 at 1.76 Angstroms resolution==
3: ...ight'caption='[[2qs3]], [[Resolution|resolution]] 1.76Å' scene=''>
6: ...y diffraction, [[Resolution|Resolution]] 1.76Å</td></tr>
7: ...OXYETHYL]-5-METHYL-2,6-DIOXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL}METHYL)-5-PHENYLTHIOPHENE-2-CARBOXYLIC+ACI...
11: ...ion from the retina to the hypothalamus.<ref>PMID:16540562</ref> - 2qs4 (4,569 bytes)
2: ...nd binding core dimer in complex with LY466195 at 1.58 Angstroms resolution==
3: ...ight'caption='[[2qs4]], [[Resolution|resolution]] 1.58Å' scene=''>
6: ...y diffraction, [[Resolution|Resolution]] 1.58Å</td></tr>
7: ...6S,8AR)-6-{[(2S)-2-CARBOXY-4,4-DIFLUOROPYRROLIDIN-1-YL]METHYL}DECAHYDROISOQUINOLINE-3-CARBOXYLIC+ACID...
11: ...ion from the retina to the hypothalamus.<ref>PMID:16540562</ref> - 4fat (4,802 bytes)
3: ...ight'caption='[[4fat]], [[Resolution|resolution]] 1.40Å' scene=''>
5: <table><tr><td colspan='2'>[[4fat]] is a 1 chain structure with sequence from [https://en.wi...
6: ...ay diffraction, [[Resolution|Resolution]] 1.4Å</td></tr>
7: ...-1H-PYRAZOL-1-YL]ACETYL}AMINO)-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE'>496</scene>, <scene...
11: ...9946266</ref> <ref>PMID:21317873</ref> <ref>PMID:21846932</ref> - 4r3c (10,226 bytes)
5: <table><tr><td colspan='2'>[[4r3c]] is a 1 chain structure with sequence from [https://en.wi...
6: ...y diffraction, [[Resolution|Resolution]] 2.06Å</td></tr>
7: ... <scene name='pdbligand=GG5:4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE'>GG5</scene></td></tr>
11: ...893488</ref> <ref>PMID:20932473</ref> <ref>PMID:20188673</ref>
14: ...ite target selectivity. As far as we are aware, MW150 is without precedent as an isoform selective p3... - GABA receptor (7,851 bytes)
1: ...aption='Glycosylated human GABAB receptor subunit 1(grey) and subunit 2 (green) (PDB code [[4mqe]])' ...
5: ...r of the vertebrate central nervous system (Kerr, 1995). GABA can bind one of two different receptor ...
6: *<scene name='89/896619/Cv/5'>Pregnenolone alone</scene>.
7: *<scene name='89/896619/Cv/4'>Pregnanolone binds beta3-alpha5 GABAA rece...
8: *<scene name='89/896619/Cv/6'>Pregnanolone binding site is situated betw... - 703DSS (10,388 bytes)
2: ...aption='5-HT3a receptor' scene='71/716487/Default/1'>
3: .... There are seven families of 5-HT receptors (5-HT1- 5-HT7), all of which function as G-protein-coup...
8: ... the relationship between structure and function. Neuropharmacology, 273-284</ref>.
11: The <scene name='71/716487/Extracellular_region/1'>extracellular region</scene> is relatively large...
12: ...the mouse serotonin 5-HT3 receptor. Nature, 276-281.</ref>. This binding pocket shrinks around agonis... - 5-ht3a receptor (10,523 bytes)
2: ...tor (PDB code [[4pir]])' scene='71/716487/Default/1'>
3: .... There are seven families of 5-HT receptors (5-HT1- 5-HT7), all of which function as G-protein-coup...
8: ... the relationship between structure and function. Neuropharmacology, 273-284</ref>.
11: The <scene name='71/716487/Extracellular_region/1'>extracellular region</scene> is relatively large...
12: ...the mouse serotonin 5-HT3 receptor. Nature, 276-281.</ref>. This binding pocket shrinks around agonis... - 5u8c (4,230 bytes)
2: ==CRYSTAL STRUCTURE OF GLUN1/GLUN2A LIGAND-BINDING DOMAIN IN COMPLEX WITH GLYC...
3: ...ight'caption='[[5u8c]], [[Resolution|resolution]] 1.60Å' scene=''>
6: ... diffraction, [[Resolution|Resolution]] 1.598Å</td></tr>
7: ...ligandDat"><scene name='pdbligand=84J:[(R)-{[(1S)-1-(4-BROMOPHENYL)ETHYL]AMINO}(2,3-DIHYDROXYQUINOXAL...
11: ...ell surface targeting of NMDA receptors.<ref>PMID:15996549</ref> - 6f25 (4,538 bytes)
6: ...fraction, [[Resolution|Resolution]] 3.0519965Å</td></tr>
7: ...-[ethyl-[(2-nitrophenyl)methyl]amino]pent-1-enyl]-1-[5-[ethyl-[(2-nitrophenyl)methyl]amino]pentyl]-6-...
11: ...:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref>
14: ... amyloid precursor protein and a human presenilin-1 mutant, C-35 (5mg/kg, i.p) and donepezil (0.75mg/...
16: ....025., Epub 2019 May 25. PMID:31132435<ref>PMID:31132435</ref> - 6cei (3,446 bytes)
5: <table><tr><td colspan='2'>[[6cei]] is a 1 chain structure with sequence from [https://en.wi...
10: [https://www.uniprot.org/uniprot/I3B1_CONGE I3B1_CONGE] May embed in the membrane and bind to the ...
13: ...e resultant disulfide connectivity forming an ICK+1 motif. With a triple stranded beta-sheet, the GXI...
15: ...J Mar Drugs. 2021 Jan 26;19(2):60. doi: 10.3390/md19020060. PMID:33530397<ref>PMID:33530397</ref> - AChE and Inhibition (13,318 bytes)
2: ...ight' caption='AChE from electric eel (PDB code [[1eea]])' scene=''>
5: ...e diseases. <ref name = "Jacob" > Jacob, L. M. (2018). Acetylcholine. Salem Press Encyclopedia of Sci...
8: ...ble from: https://www.ncbi.nlm.nih.gov/books/NBK11143/ </ref>
11: ...nd toxicology. Current neuropharmacology, 11(3), 315-35. </ref>
14: ...ar junction. Chemico-biological interactions, 175(1-3), 26-9. </ref> - 7rec (4,670 bytes)
2: ...Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CaMKII...
6: ...ay diffraction, [[Resolution|Resolution]] 2.2Å</td></tr>
14: ...nalogs as powerful tools for investigating CaMKII neuropharmacology in general and as potential therapeutic compounds...
16: ...(31). pii: 2108079118. doi:, 10.1073/pnas.2108079118. PMID:34330837<ref>PMID:34330837</ref> - Proteopedia:I3DC (64,070 bytes)
4: ...Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular d...
5: # [[Journal:Acta Cryst D:S2059798318000050|A DNA structural alphabet provides new ins...
6: ...ryst D:S2059798318014900| Structure of the AmyC GH13 alpha-amylase from ''Alicyclobacillus sp'', reve...
7: ...Myotis davidii'' and the impact of interdomain ISG15 interactions on viral protein engagement ]], Car...
8: ...tylglucosamine 2-epimerase from ''Nostoc sp.'' KVJ10 reveals the true dimer]], Marie-Josee Haglund Ha...
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