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Article title matches

  1. Category:Nrf2 regulation (46 bytes)
    1: List of pages with the keyword Nrf2 regulation
  2. Category:Nrf2 (35 bytes)
    1: List of pages with the keyword Nrf2
  3. Category:Nrf2 activator (45 bytes)
    1: List of pages with the keyword Nrf2 activator
  4. Category:Keap1-nrf2 system (48 bytes)
    1: List of pages with the keyword Keap1-nrf2 system
  5. Image:Nrf2.jpg (0 bytes)
  6. Image:Inputs and outputs of KEAP1 NRF2 pathway.jpg (62 bytes)

Page text matches

  1. 9f2p (4,238 bytes)
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    14: ... in the design of potent and more drug-like Keap1-Nrf2 inhibitors.
    16: ...ve Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors.,Qin Y, Poulsen C, Narayanan D, Chan C...
  2. 9f2q (4,314 bytes)
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    14: ... in the design of potent and more drug-like Keap1-Nrf2 inhibitors.
    16: ...ve Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors.,Qin Y, Poulsen C, Narayanan D, Chan C...
  3. 4iqk (3,216 bytes)
    14: ...d X-ray crystallography. One compound upregulates Nrf2 response genes measured by a luciferase cell repo...
    16: Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent...
  4. 9etx (3,458 bytes)
    14: The NRF2-KEAP1 interaction is central for cytoprotection a...
  5. 9ety (3,598 bytes)
    14: The NRF2-KEAP1 interaction is central for cytoprotection a...
  6. 2flu (3,777 bytes)
    23: ...rf2 to Keap1 and for Keap1-mediated repression of Nrf2-dependent gene expression. Our results provide a ...
    25: ...:Nrf2 interface provides mechanistic insight into Nrf2 signaling.,Lo SC, Li X, Henzl MT, Beamer LJ, Hann...
  7. 8q1q (3,525 bytes)
    12: ...ained and functionalised peptides that target the Nrf2/Keap1 PPI. The most promising peptide, P8-H conta...
    14: A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.,Iegre J, Krajc...
  8. 8q1r (4,189 bytes)
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    14: ...ained and functionalised peptides that target the Nrf2/Keap1 PPI. The most promising peptide, P8-H conta...
    16: A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.,Iegre J, Krajc...
  9. 9uo8 (4,378 bytes)
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    14: ...de is a promising compound for the development of Nrf2 activators that can be applied to treat inflammat...
    16: ...in Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, an...
  10. 3zgc (3,684 bytes)
    14: ...in (1.98 A resolution) and of the complex with an Nrf2-derived peptide obtained by soaking (2.20 A resol...
  11. 3zgd (3,727 bytes)
    14: ...in (1.98 A resolution) and of the complex with an Nrf2-derived peptide obtained by soaking (2.20 A resol...
  12. 1x2j (3,310 bytes)
    2: ... mutations in the repression activity of Keap1 on Nrf2==
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
  13. 1x2r (4,832 bytes)
    2: ... mutations in the repression activity of Keap1 on Nrf2==
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    24: ... basis for the loss of Keap1 function and gain of Nrf2 function.
  14. 2dyh (4,689 bytes)
    2: ...in in complexed with the N-terminal region of the Nrf2 transcription factor==
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    24: ...orks to correctly position the lysines within the Nrf2 Neh2 domain for efficient ubiquitination. Togethe...
  15. 4h10 (6,697 bytes)
    10: ...on via the regulation of antioxidant genes NFE2L2/NRF2 and its targets SESN2, PRDX3, CCLC and CCLM. Nega...
  16. 2z32 (4,613 bytes)
    11: ...e complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteas...
    24: ...hat the DLG and ETGE motifs of the Neh2 domain of Nrf2 and the ProTalpha peptide bind to Keap1 in a simi...
  17. 2vpj (5,890 bytes)
    24: ...is E3 class that supports the bivalent capture of Nrf2 and reveals potential new sites for E3 inhibitor ...
  18. Category:Nrf2 regulation (46 bytes)
    1: List of pages with the keyword Nrf2 regulation
  19. 8xgk (3,813 bytes)
    2: ...s for Identification of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction Ihhibitors==
    14: ...ted the discovery of novel and bioavailable Keap1-Nrf2 PPI inhibitor 8 which exhibited moderate in vivo ...
    16: ...s for Identification of Novel Highly Potent Keap1-Nrf2 Protein-Protein Interaction Inhibitors.,Otake K, ...
  20. 4in4 (3,332 bytes)
    14: ...d X-ray crystallography. One compound upregulates Nrf2 response genes measured by a luciferase cell repo...
    16: Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent...

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