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- Category:Odcase (37 bytes)
1: List of pages with the keyword Odcase
Page text matches
- 1jjk (4,679 bytes)
24: ...fined medium during expression. SeMet-substituted ODCase in complex with the inhibitor 1-(5'-phospho-beta-... - 1km3 (2,699 bytes)
2: ==crystal structure of ODCase mutant K42A complexed with 6-azaUMP== - 1km4 (4,332 bytes)
2: ==crystal structure of ODCase mutant K72A complexed with UMP== - 1km5 (2,751 bytes)
2: ==Crystal structure of ODCase mutant D75N complexed with 6-azaUMP== - 1km6 (2,694 bytes)
2: ==Crystal structure of ODCase mutant D70AK72A complexed with OMP== - 1l2u (4,234 bytes)
23: ...BMP) and the Methanobacterium thermoautotrophicum ODCase structures (with and without 6-aza UMP) show very... - 1x1z (4,235 bytes)
1: ==Orotidine 5'-monophosphate decarboxylase (odcase) complexed with BMP (produced from 6-cyanoump)==
24: ...osition, leading to inhibition. This potential of ODCase is very useful in the design of novel inhibitors.
26: An unprecedented twist to ODCase catalytic activity.,Fujihashi M, Bello AM, Poduch... - 2e6y (4,600 bytes)
2: ...plex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP==
24: ...5'-monophosphate is a novel covalent inhibitor of ODCase, and its nucleoside analogue paves the way to a n... - 2q8z (4,484 bytes)
24: ...e is a potent covalent inhibitor of P. falciparum ODCase. 6-Methyluridine exhibited weak antimalarial acti... - 3bar (4,265 bytes)
24: ...e is a potent covalent inhibitor of P. falciparum ODCase. 6-Methyluridine exhibited weak antimalarial acti... - 2qaf (4,315 bytes)
24: ...e is a potent covalent inhibitor of P. falciparum ODCase. 6-Methyluridine exhibited weak antimalarial acti... - Category:Odcase (37 bytes)
1: List of pages with the keyword Odcase - 4hib (4,060 bytes)
16: ...he potential of transformation of poor ligands to ODCase into novel inhibitors of this drug target. - 3g3d (4,863 bytes)
26: ...oro-6-iodo derivatives are covalent inhibitors of ODCase, and the active site Lys145 residue covalently bi... - 3g3m (4,818 bytes)
26: ...oro-6-iodo derivatives are covalent inhibitors of ODCase, and the active site Lys145 residue covalently bi... - 3mi2 (4,740 bytes)
26: ...ine. All these ligands bind in the active site of ODCase exhibiting distinct interactions paving the way t... - 3mo7 (4,288 bytes)
16: ...tides and thus interactions in the active site of ODCase. Molecular interactions of the 2'-fluorinated nuc... - Sandbox Reserved 315 (7,586 bytes)
6: ...t can form a dimeric enzyme by binding to another ODCase<ref name = "Wu"/>. In multi-cellular organisms it...
11: ...aption='ODCase dimer' scene='Sandbox_Reserved_315/Odcase_dimer/1'/>
13: ...ed to a second ODCase<ref name = "Miller"/>. Each ODCase has 9 α helices that encompass 8 internal β she...
19: ... (PRPP)<Ref name = "Brosnan">PMID:17513443</ref>. ODCase then decarboxylated OMP to form uridine monophosp...
24: ...rtly regulates pyrimidine synthesis. Mutations in ODCase are genetically inherited and can cause [http://e... - 3wjw (3,917 bytes)
14: ...DeltaG() value. These results are consistent with ODCase using both substrate distortion and transition-st... - 3wjx (3,956 bytes)
14: ...DeltaG() value. These results are consistent with ODCase using both substrate distortion and transition-st...
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