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- Category:Orexin (37 bytes)
1: List of pages with the keyword Orexin - Category:Orexin neurotransmitter (54 bytes)
1: List of pages with the keyword Orexin neurotransmitter - Category:Orexin-a (39 bytes)
1: List of pages with the keyword Orexin-a - Category:Orexin-b (39 bytes)
1: List of pages with the keyword Orexin-b - Category:Orexin receptor (46 bytes)
1: List of pages with the keyword Orexin receptor - Category:Orexin 2 receptor (48 bytes)
1: List of pages with the keyword Orexin 2 receptor - Orexin and Orexin receptor (3,584 bytes)
1: ...oad='4s0v' size='400' side='right' caption='Human orexin receptor complex with insomnia medication belsomr...
6: ...o Orexin receptor type 2 a majority of the time. Orexin-A has shown an equal selectivity at both types of...
14: Defects in orexin signaling are responsible for the human diseases ...
18: ...tor antagonist, and has the ability to block both Orexin receptors 1 and 2, thus inhibiting the neuropepti...
29: == 3D Structures of orexin and orexin receptor ==
Page text matches
- 1uvq (4,345 bytes)
35: *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] - 1cq0 (2,929 bytes)
2: ...EXIN-B'SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B '==
10: ...psy is associated with a deficient orexin system. Orexins are absent and/or greatly diminished in the brai...
12: ... both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity...
15: *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] - 1r02 (4,059 bytes)
2: ==Solution structure of Human Orexin-A:Regulator of Appetite and Wakefulness==
10: ...psy is associated with a deficient orexin system. Orexins are absent and/or greatly diminished in the brai...
12: ... both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity...
15: ...vious mutagenic studies, the derived structure of orexin-A provides us with a structure-functional view fo...
17: Solution structure of human orexin-A: regulator of appetite and wakefulness.,Kim HY,... - 1wso (5,642 bytes)
2: ==The solution structures of human Orexin-A==
11: ...psy is associated with a deficient orexin system. Orexins are absent and/or greatly diminished in the brai...
13: ... both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity...
16: ...n of orexin-A is important for the preference for orexin-A of OX(1)R.
18: ...e structural basis of specific recognition by the orexin-1 receptor.,Takai T, Takaya T, Nakano M, Akutsu H... - Category:Orexin (37 bytes)
1: List of pages with the keyword Orexin - User:Alexander Berchansky (31,370 bytes)
403: *[[Orexin and Orexin receptor]] - Proteopedia:Structure Index/L-Q (10,420 bytes)
174: *** [[Orexin and Orexin receptor]] - G protein-coupled receptor (14,857 bytes)
43: ====Orexin receptor====
44: * [[Orexin and Orexin receptor]]
45: * [[Belsomra]] and Orexin receptors - 4s0v (4,181 bytes)
2: ==Crystal structure of the human OX2 orexin receptor bound to the insomnia drug Suvorexant==
11: ...ive, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
14: ...ognition and will aid further efforts to modulate orexin signalling for therapeutic ends.
16: Crystal structure of the human OX orexin receptor bound to the insomnia drug suvorexant.,Y...
23: *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] - Category:Orexin neurotransmitter (54 bytes)
1: List of pages with the keyword Orexin neurotransmitter - Category:Orexin-a (39 bytes)
1: List of pages with the keyword Orexin-a - Category:Orexin-b (39 bytes)
1: List of pages with the keyword Orexin-b - Category:Orexin receptor (46 bytes)
1: List of pages with the keyword Orexin receptor - 4zj8 (4,090 bytes)
2: ==Structures of the human OX1 orexin receptor bound to selective and dual antagonists=...
11: ...ptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled t...
14: ...tools for the design and development of selective orexin-receptor antagonists and agonists.
16: ...ligand-binding mechanism of the human OX1 and OX2 orexin receptors.,Yin J, Babaoglu K, Brautigam CA, Clark...
23: *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] - 4zjc (4,092 bytes)
2: ==Structures of the human OX1 orexin receptor bound to selective and dual antagonists=...
11: ...ptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled t...
14: ...tools for the design and development of selective orexin-receptor antagonists and agonists.
16: ...ligand-binding mechanism of the human OX1 and OX2 orexin receptors.,Yin J, Babaoglu K, Brautigam CA, Clark...
23: *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] - Monoclonal Antibodies 3D structures (46,151 bytes)
134: **[[7sqo]] – syscFv in orexin receptor – Cryo EM<br /> - Belsomra (6,144 bytes)
3: ...to cause alertness and wakefulness. By targeting orexin's receptors, Belsomra cuts off the signals causin...
5: ...tor antagonist, and has the ability to block both Orexin receptors 1 and 2, thus inhibiting the neuropepti...
8: ... name="six" />. Structural differences of the two orexin receptors’ binding sites involve only two amino...
11: ...usal, while showing little activity during sleep. Orexins show little activity during sleep because the sy...
12: ...the symptoms of narcolepsy, as the already little orexin activity would be diminished at great risk to pat... - 5wqc (4,319 bytes)
2: ==Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA...
11: ...ive, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
14: ...uld facilitate the development of antagonists for orexin receptors.
16: Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagon...
40: [[Category: Orexin 2 receptor]] - 5ws3 (4,653 bytes)
2: ==Crystal structures of human orexin 2 receptor bound to the selective antagonist EMPA...
11: ...ive, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
14: ...uld facilitate the development of antagonists for orexin receptors.
16: Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagon...
23: *[[Orexin and Orexin receptor|Orexin and Orexin receptor]] - Category:Orexin 2 receptor (48 bytes)
1: List of pages with the keyword Orexin 2 receptor
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