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Article title matches
- Category:Phosphodiesterase 10a pde10a pde inhibitor (73 bytes)
1: ...t of pages with the keyword Phosphodiesterase 10a pde10a pde inhibitor - Category:Pde10a (37 bytes)
1: List of pages with the keyword Pde10a - Category:Pde10a inhibitor (47 bytes)
1: List of pages with the keyword Pde10a inhibitor
Page text matches
- 4hf4 (3,232 bytes)
2: ==Crystal Structure of PDE10A with a biaryl ether inhibitor (1-(1-(3-(4-(benzo[...
14: ... novel binding modes to the catalytic site of the PDE10A enzyme.
16: Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation... - 2oup (2,784 bytes)
2: ==crystal structure of PDE10A== - 4bbx (3,962 bytes)
2: ...iscovery of a potent, selective and orally active PDE10A inhibitor for the treatment of schizophrenia==
14: ...hibitor of PDE10A with high striatal occupancy of PDE10A, promising in vivo efficacy in different rodent b...
16: ...iscovery of a potent, selective and orally active PDE10A inhibitor for the potential treatment of schizoph... - 2ovv (3,981 bytes)
24: ...otent and selective brain penetrable inhibitor of PDE10A.
26: ...a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.,Chappie TA, Humphrey JM, Allen MP, Es... - 2zmf (6,026 bytes)
8: ..."><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE10A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/w...
26: ...he adenine base is specifically recognized by the PDE10A GAF-B domain in a unique manner, through residues... - 4heu (3,180 bytes)
2: ==Crystal Structure of PDE10A with a biaryl ether inhibitor ((1-(3-(4-((1H-benz...
14: ... novel binding modes to the catalytic site of the PDE10A enzyme.
16: Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation... - 2wey (4,759 bytes)
24: .... Using crystals of human phosphodiesterase 10a (hPDE10a) as an example of such a challenging crystallogra...
26: ...igand crystal complexes, exemplified by the human PDE10a-papaverine structure.,Andersen OA, Schonfeld DL, ... - 3hqw (4,342 bytes)
2: ==Discovery of novel inhibitors of PDE10A==
24: ...3-yl)-phenoxymethyl]-quinoline (PF-2545920). This PDE10A inhibitor is the first reported clinical entry fo...
26: ... Schizophrenia (dagger) dagger Coordinates of the PDE10A crystal structures have been deposited in the Pro... - 3hqy (4,410 bytes)
2: ==Discovery of novel inhibitors of PDE10A==
24: ...3-yl)-phenoxymethyl]-quinoline (PF-2545920). This PDE10A inhibitor is the first reported clinical entry fo...
26: ... Schizophrenia (dagger) dagger Coordinates of the PDE10A crystal structures have been deposited in the Pro... - 3hqz (4,404 bytes)
2: ==Discovery of novel inhibitors of PDE10A==
24: ...3-yl)-phenoxymethyl]-quinoline (PF-2545920). This PDE10A inhibitor is the first reported clinical entry fo...
26: ... Schizophrenia (dagger) dagger Coordinates of the PDE10A crystal structures have been deposited in the Pro... - 3hr1 (4,414 bytes)
2: ==Discovery of novel inhibitors of PDE10A==
24: ...3-yl)-phenoxymethyl]-quinoline (PF-2545920). This PDE10A inhibitor is the first reported clinical entry fo...
26: ... Schizophrenia (dagger) dagger Coordinates of the PDE10A crystal structures have been deposited in the Pro... - Category:Phosphodiesterase 10a pde10a pde inhibitor (73 bytes)
1: ...t of pages with the keyword Phosphodiesterase 10a pde10a pde inhibitor - 2y0j (3,325 bytes)
2: ...olines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors, part 2, Lead-optimisation.==
14: ... novel binding modes to the catalytic site of the PDE10A enzyme.
16: ...olines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors.,Kehler J, Ritzen A, Langgard M, Pete... - 9jdu (2,108 bytes)
2: ==The crystal structure of PDE10A complexed with inhibitor 2061== - 4ael (3,175 bytes)
2: ==PDE10A in complex with the inhibitor AZ5==
14: ... was synthesized as potent phosphodiesterase 10A (PDE10A) inhibitors. Structure-based chemical modificatio...
16: ...naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors.,Bauer U, Giordanetto F, Bauer M, O'Ma... - 4ddl (3,427 bytes)
2: ==PDE10a Crystal Structure Complexed with Novel Inhibitor=...
14: ...d in compound 39, a promising potent inhibitor of PDE10A with good in vivo metabolic stability in rats and...
16: ...n-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors.,Hu E, Kunz RK, Rumfelt S, Chen N, Bu... - 4dff (3,525 bytes)
14: ...ound 35 as a potent, selective, and orally active PDE10A inhibitor. Compound 35 inhibited MK-801-induced h... - 9ja8 (4,677 bytes)
14: ...Our findings suggest that effective inhibition of PDE10A potentially confers a protective effect on FMT in... - 4lkq (4,054 bytes)
2: ==Crystal structure of PDE10A2 with fragment ZT017==
14: ...elding high-resolution co-crystal structures with PDE10A. The structural information was used to elaborate...
16: Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nano... - 4llj (4,021 bytes)
2: ==Crystal structure of PDE10A2 with fragment ZT214==
14: ...elding high-resolution co-crystal structures with PDE10A. The structural information was used to elaborate...
16: Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nano...
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