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Article title matches
- Category:Pde4 inhibitor (45 bytes)
1: List of pages with the keyword Pde4 inhibitor - Category:Pde4 (35 bytes)
1: List of pages with the keyword Pde4 - Category:Pde4-camp complex (48 bytes)
1: List of pages with the keyword Pde4-camp complex - Category:Natural pde4 inhibtor (52 bytes)
1: List of pages with the keyword Natural pde4 inhibtor
Page text matches
- 8w4q (5,023 bytes)
2: ==Crystal structure of PDE4D complexed with CX-4945==
11: ...ke has to be considered with caution. Defects in PDE4D are the cause of acrodysostosis type 2, with or ...
13: [https://www.uniprot.org/uniprot/PDE4D_HUMAN PDE4D_HUMAN] Hydrolyzes the second messenger cAMP, whi...
16: ...ed drug design in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for effi...
18: ... repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao... - 8w4r (5,049 bytes)
2: ==Crystal structure of PDE4D complexed with CVT-313==
11: ...ke has to be considered with caution. Defects in PDE4D are the cause of acrodysostosis type 2, with or ...
13: [https://www.uniprot.org/uniprot/PDE4D_HUMAN PDE4D_HUMAN] Hydrolyzes the second messenger cAMP, whi...
16: ...ed drug design in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for effi...
18: ... repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao... - 8w4s (4,130 bytes)
14: ...ed drug design in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for effi...
16: ... repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao... - 8w4t (4,138 bytes)
14: ...ed drug design in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for effi...
16: ... repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao... - 1ptw (3,618 bytes)
2: ==The Crystal Structure of AMP-Bound PDE4 Suggests a Mechanism for Phosphodiesterase Cataly...
11: ...ke has to be considered with caution. Defects in PDE4D are the cause of acrodysostosis type 2, with or ...
13: [https://www.uniprot.org/uniprot/PDE4D_HUMAN PDE4D_HUMAN] Hydrolyzes the second messenger cAMP, whi... - 1ror (4,580 bytes)
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
24: ...ned crystal structures of the catalytic domain of PDE4B complexed with AMP (2.0 A), 8-Br-AMP (2.13 A) an... - 1udt (4,824 bytes)
24: ...tors as therapeutic drugs, only the cAMP-specific PDE4 structures are currently available. Here we prese... - 1udu (4,815 bytes)
24: ...tors as therapeutic drugs, only the cAMP-specific PDE4 structures are currently available. Here we prese... - 1uho (4,822 bytes)
24: ...tors as therapeutic drugs, only the cAMP-specific PDE4 structures are currently available. Here we prese... - 1y2h (5,075 bytes)
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
24: ...s of seven pyrazole derivatives bound to PDE4B or PDE4D, revealing the robustness of this approach for i... - 1y2j (5,074 bytes)
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
24: ...s of seven pyrazole derivatives bound to PDE4B or PDE4D, revealing the robustness of this approach for i... - 3w5e (3,722 bytes)
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
14: ... the new inhibitor (31e) in the catalytic site of PDE4B is presented based on an X-ray crystal structure...
16: ...-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.,Goto T, Shiina A, Yoshino T, Mizukami... - Category:Pde4 inhibitor (45 bytes)
1: List of pages with the keyword Pde4 inhibitor - Category:Pde4 (35 bytes)
1: List of pages with the keyword Pde4 - Category:Pde4-camp complex (48 bytes)
1: List of pages with the keyword Pde4-camp complex - 3d3p (4,324 bytes)
2: ==Crystal structure of PDE4B catalytic domain in complex with a pyrazolopyrid...
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
24: ...ridine 20a was found to be a potent and selective PDE4 inhibitor which also inhibits LPS induced TNF-alp...
26: ... a novel structural class of potent and selective PDE4 inhibitors.,Hamblin JN, Angell TD, Ballantine SP,... - 1jp1 (2,980 bytes)
11: ...g to the enzyme active site. The binding of other PDE4 inhibitors (high- and low-affinity) was also mode... - 1jp2 (3,003 bytes)
11: ...g to the enzyme active site. The binding of other PDE4 inhibitors (high- and low-affinity) was also mode... - 3frg (4,056 bytes)
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
24: ...at were highly potent and selective inhibitors of PDE4 with a good pharmacokinetic profile in the rat. Q...
26: ... a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.... - 3gwt (4,281 bytes)
11: [https://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN] Hydrolyzes the second messenger cAMP, whi...
24: ... series has been optimized to GSK256066, a potent PDE4B inhibitor which also inhibits LPS induced produc...
26: ... a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administrati...
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