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Article title matches
- Category:Pde5 (35 bytes)
1: List of pages with the keyword Pde5 - Category:Pde5 inhibitor complex (53 bytes)
1: List of pages with the keyword Pde5 inhibitor complex - Category:Pde5-inhibitor potency (53 bytes)
1: List of pages with the keyword Pde5-inhibitor potency - Category:Pde5 inhibitor (45 bytes)
1: List of pages with the keyword Pde5 inhibitor - Category:Pde5 inhibitor lw1634 (52 bytes)
1: List of pages with the keyword Pde5 inhibitor lw1634 - Category:Pde5 in complex with inhibitor lw1805 (68 bytes)
1: List of pages with the keyword Pde5 in complex with inhibitor lw1805
Page text matches
- 2chm (3,621 bytes)
2: ...yrazolo pyrimidinones - a flipped binding mode in PDE5==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re... - 8w4q (5,023 bytes)
16: ...esign in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for efficient dis...
18: ...ing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao Q, Zou Y... - 8w4r (5,049 bytes)
16: ...esign in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for efficient dis...
18: ...ing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao Q, Zou Y... - 8w4s (4,130 bytes)
2: ==Crystal structure of PDE5A in complex with CVT-313==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
14: ...esign in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for efficient dis...
16: ...ing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao Q, Zou Y... - 8w4t (4,138 bytes)
2: ==Crystal structure of PDE5A in complex with a novel inhibitor==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
14: ...esign in identifying novel inhibitors of PDE4 and PDE5, which provides a prime example for efficient dis...
16: ...ing and structure-based discovery of new PDE4 and PDE5 inhibitors.,Liu J, Zhang X, Chen G, Shao Q, Zou Y... - 1udt (4,824 bytes)
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ... the catalytic domain (residues 537-860) of human PDE5 complexed with the three drug molecules sildenafi... - 1udu (4,815 bytes)
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ... the catalytic domain (residues 537-860) of human PDE5 complexed with the three drug molecules sildenafi... - 1uho (4,822 bytes)
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ... the catalytic domain (residues 537-860) of human PDE5 complexed with the three drug molecules sildenafi... - 2h40 (4,376 bytes)
2: ...l structure of the catalytic domain of unliganded PDE5==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ...res of chimerically hybridized or almost inactive PDE5. Mutagenesis and kinetic analyses confirm that th... - 2h42 (4,323 bytes)
2: ==Crystal structure of PDE5 in complex with sildenafil==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ...res of chimerically hybridized or almost inactive PDE5. Mutagenesis and kinetic analyses confirm that th... - 2h44 (4,318 bytes)
2: ==Crystal structure of PDE5A1 in complex with icarisid II==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ...res of chimerically hybridized or almost inactive PDE5. Mutagenesis and kinetic analyses confirm that th... - 2ju4 (4,339 bytes)
24: ...eraction between PDEgamma(46-87) and the chimeric PDE5/6 catalytic domain confirmed that C-terminal resi... - 4i9z (3,399 bytes)
2: ==Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibito...
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
14: ...mpound 13a has the highest inhibition activity to PDE5 (IC50, 1.7 nM).
16: ...bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.,Gong X, Wang G, Ren J, Liu Z, Wang Z, Chen T, Ya... - 4ia0 (3,329 bytes)
2: ==Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibito...
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
14: ...mpound 13a has the highest inhibition activity to PDE5 (IC50, 1.7 nM).
16: ...bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.,Gong X, Wang G, Ren J, Liu Z, Wang Z, Chen T, Ya... - Category:Pde5 (35 bytes)
1: List of pages with the keyword Pde5 - Category:Pde5 inhibitor complex (53 bytes)
1: List of pages with the keyword Pde5 inhibitor complex - Category:Pde5-inhibitor potency (53 bytes)
1: List of pages with the keyword Pde5-inhibitor potency - 2k31 (4,975 bytes)
11: [https://www.uniprot.org/uniprot/PDE5A_MOUSE PDE5A_MOUSE] Plays a role in signal transduction by re...
24: ...PDE5 and the design of GAF-specific regulators of PDE5 function. - 3hc8 (4,203 bytes)
2: ==Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Ce...
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ...properties of the aminopyridiopyrazinone class of PDE5 inhibitors through modification of the core ring ...
26: Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the ce... - 3hdz (4,310 bytes)
2: ...ed Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors==
11: [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by re...
24: ...b]pyrazinones which show potent inhibition of the PDE5 enzyme. Synthetic details and some structure-acti...
26: ...d pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors.,Owen DR, Walker JK, Jon Jacobsen E, F...
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