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Article title matches
- Category:Pfdhfr (37 bytes)
1: List of pages with the keyword Pfdhfr
Page text matches
- Malarial Dihydrofolate Reductase as Drug Target (10,680 bytes)
4: ...e='right' caption='Crystal structure of Wild-type PfDHFR-TS COMPLEXED WITH NADPH, dUMP AND PYRIMETHAMINE (...
5: Mutant, Drug Resistant PfDHFR
8: ...t/Quadruple_mutant/2'>quadruple mutant</scene> of PfDHFR has four
9: ...e mutant must be addressed in the research of new PfDHFR targeting drugs.
15: ...210 was effective at getting deep into the mutant PfDHFR active site, its protonated state in the acidic g... - 1j3i (4,883 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP==
24: ...ibuting to binding. The single-chain bifunctional PfDHFR-TS has a helical insert between the DHFR and TS d... - 1j3j (4,866 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP...
24: ...ibuting to binding. The single-chain bifunctional PfDHFR-TS has a helical insert between the DHFR and TS d... - 1j3k (4,913 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP==
24: ...ibuting to binding. The single-chain bifunctional PfDHFR-TS has a helical insert between the DHFR and TS d... - 3dg8 (5,456 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP== - 3dga (5,441 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF01302, NADPH, and dUMP== - 3jsu (5,308 bytes)
2: ...arum dihydrofolate reductase-thymidylate synthase(PFDHFR-TS) complexed with QN254, NADPH, and dUMP== - 3qg2 (4,503 bytes)
14: ...inding space similarly to what is observed in the PfDHFR structures. Natural resistance to antifolates of ... - 3qgt (4,356 bytes)
2: ==Crystal structure of Wild-type PfDHFR-TS COMPLEXED WITH NADPH, dUMP AND PYRIMETHAMINE==
14: ...inding space similarly to what is observed in the PfDHFR structures. Natural resistance to antifolates of ... - 6lh9 (4,147 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 46 and NADPH==
14: ...to inhibit P. falciparum dihydrofolate reductase (PfDHFR) of the wild type or those carrying either single... - 6lhi (4,228 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with C466 (compound 42) and NADPH==
14: ...to inhibit P. falciparum dihydrofolate reductase (PfDHFR) of the wild type or those carrying either single... - 6lhj (4,220 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with C452 (compound 16) and NADPH==
14: ...to inhibit P. falciparum dihydrofolate reductase (PfDHFR) of the wild type or those carrying either single... - 4dpd (4,982 bytes)
2: ...RUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PfDHFR-TS), DHF COMPLEX, NADP+, dUMP==
14: ...gs the target residence time. P218, when bound to PfDHFR-TS, resides almost entirely within the envelope m... - 4dph (5,155 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with P65 and NADPH==
14: ...gs the target residence time. P218, when bound to PfDHFR-TS, resides almost entirely within the envelope m... - 4dp3 (5,100 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with P218 and NADPH==
14: ...gs the target residence time. P218, when bound to PfDHFR-TS, resides almost entirely within the envelope m... - 3um5 (4,427 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, an...
14: ...ion 16. Crystal structure analyses reveal that in PfDHFR-TS variant T9/94 (A16V+S108T) complexed with CYC,... - 4ddr (5,770 bytes)
16: ...gs the target residence time. P218, when bound to PfDHFR-TS, resides almost entirely within the envelope m... - 8jfb (2,252 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 4 (B21588), NADPH and... - 8jfc (2,301 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 6 (B21591), NADPH and... - 8jfd (2,301 bytes)
2: ...rum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 8 (B21594), NADPH and...
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