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  1. 1zs0 (4,595 bytes)
    24: ...zinc-binding group (ZBG). alpha-Arylsulfonylamino phosphonates incorporate a particularly favorable combination ...
    26: ...e inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.,Pochetti G, Gavuzzo E, Campestre C, Agamennone M...
  2. 1zvx (4,517 bytes)
    24: ...zinc-binding group (ZBG). alpha-Arylsulfonylamino phosphonates incorporate a particularly favorable combination ...
    26: ...e inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.,Pochetti G, Gavuzzo E, Campestre C, Agamennone M...
  3. 1kn2 (3,659 bytes)
    24: ...prisingly, the electron densities of the liganded phosphonates, 7D and 7L, within the D2.3 binding/reaction site...
  4. 1kn4 (3,659 bytes)
    24: ...prisingly, the electron densities of the liganded phosphonates, 7D and 7L, within the D2.3 binding/reaction site...
  5. 8cpa (5,753 bytes)
    24: ...atalyzed reaction. The phosphinyl groups of these phosphonates coordinate to the active-site zinc in a manner th...
  6. 7cpa (5,769 bytes)
    24: ...atalyzed reaction. The phosphinyl groups of these phosphonates coordinate to the active-site zinc in a manner th...
  7. 6cpa (5,276 bytes)
    24: ...tidase A with great affinity (Ki = 3 pM). Similar phosphonates have been shown to be transition-state analogues ...
  8. 4i3u (3,746 bytes)
    14: ...ion. For example, most common naturally occurring phosphonates can be catabolized to either phosphonoacetaldehyd...
  9. 3zcz (4,118 bytes)
    14: ...should be considered along with boronic acids and phosphonates as a warhead that can be incorporated into new an...
  10. 1m32 (4,367 bytes)
    24: ...phosphonate (AEP) is a precursor of many cellular phosphonates. AEP transaminase (AEPT) is an enzyme essential t...
  11. 1nki (4,822 bytes)
    24: ...ne oxygen in the transition state. Several simple phosphonates, including the antiviral compound phosphonoformat...
  12. 1nnr (4,803 bytes)
    24: ...ne oxygen in the transition state. Several simple phosphonates, including the antiviral compound phosphonoformat...
  13. 1pym (4,993 bytes)
    24: ... The first obligatory step in the biosynthesis of phosphonates is the formation of a carbon-phosphorus bond by c...
  14. 1x8r (5,061 bytes)
    24: ...tructures of EPSPS liganded with the (S)- and (R)-phosphonates, at 1.5 and 1.9 A resolution, respectively, revea...
  15. 1x8t (5,061 bytes)
    24: ...tructures of EPSPS liganded with the (S)- and (R)-phosphonates, at 1.5 and 1.9 A resolution, respectively, revea...
  16. Organic anion transporters (34,413 bytes)
    110: ...show normal renal clearance of acyclic nucleoside phosphonates.
  17. 2ai1 (4,241 bytes)
    24: ... PNP with substrates and products. The nucleoside phosphonates contain an acetal linkage at the O2' and O3' posi...
  18. 2ai2 (4,257 bytes)
    24: ... PNP with substrates and products. The nucleoside phosphonates contain an acetal linkage at the O2' and O3' posi...
  19. 2ai3 (4,235 bytes)
    24: ... PNP with substrates and products. The nucleoside phosphonates contain an acetal linkage at the O2' and O3' posi...
  20. 2fsu (4,488 bytes)
    24: ...vely allow the internalization and degradation of phosphonates. Here we report the X-ray crystal structure of th...

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