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Article title matches

1. Image:PONATINIB.jpg (22 bytes)
   1: Ponatinib bound to Abl
2. Category:Ponatinib (40 bytes)
   1: List of pages with the keyword Ponatinib

Page text matches

1. 3zos (4,059 bytes)
   2: ...ructure of the DDR1 kinase domain in complex with ponatinib==
   14: ...ated outside the ATP pocket. Whereas imatinib and ponatinib bind potently to both the DDR and ABL kinases, th...
2. SandboxPKA (24,333 bytes)
   138: ==== Ponatinib (AP24534)====
   140: [[Image:PONATINIB.jpg|thumb|left|Ponatinib bound to Abl]]
   142: Ponatinib was identified using structure base drug design a...
   144: <scene name='SandboxPKA/Ponatinib_bound_to_abl/1'>Ponatinib bound to c-Abl kinase domain</scene>
   145: <scene name='52/521153/Ponatinib_bound_to_abl/2'>Ponatinib bound to c-Abl kinase domain</scene>
3. Bcr-Abl and Imatinib (STI571 or Gleevec) (24,270 bytes)
   137: ==== Ponatinib (AP24534)====
   139: [[Image:PONATINIB.jpg|thumb|400px|left|Ponatinib bound to Abl]]
   141: Ponatinib was identified using structure base drug design a...
   143: <scene name='52/521153/Ponatinib_bound_to_abl/2'>Ponatinib bound to c-Abl kinase domain</scene>
4. 3oxz (6,270 bytes)
   14: ...utations. The inhibitory mechanism exemplified by ponatinib may have broad relevance to designing inhibitors ...
   16: Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibito...
5. 3oy3 (6,337 bytes)
   14: ...utations. The inhibitory mechanism exemplified by ponatinib may have broad relevance to designing inhibitors ...
   16: Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibito...
6. Sandbox423 (4,126 bytes)
   16: ...onnor Walsh -- fibroblast growth factor receptor/ Ponatinib (cancer)(4uxq)
7. Student Projects for UMass Chemistry 423 Spring 2016 (14,869 bytes)
   139: ...onnor Walsh -- fibroblast growth factor receptor/ Ponatinib (cancer)(4uxq)
8. Sandbox Reserved 425 (9,939 bytes)
   5: =='''Fibroblast Growth Factor Receptor/Ponatinib (4uxq) <ref name="one">PMID: 25465127</ref>'''==
   9: ... load='4uxq' size='350' side='right' caption='The Ponatinib-FGFR complex is highly effective for treating CML...
   15: ...-ABL flipped out of its hydrophobic binding site. Ponatinib is the first of its kind to be able to inhibit th...
   17: Ponatinib's harmful side effects have caused it to fall und...
   21: ...secondary structure</scene>, FGFR in complex with Ponatinib consists of two domains, which is the characteris...
9. Image:PONATINIB.jpg (22 bytes)
   1: Ponatinib bound to Abl
10. 4bkj (4,048 bytes)
    14: ...ated outside the ATP pocket. Whereas imatinib and ponatinib bind potently to both the DDR and ABL kinases, th...
11. 4c8b (4,866 bytes)
    2: ... the kinase domain of human RIPK2 in complex with ponatinib==
    14: ...ned the first crystal structure of RIPK2 bound to ponatinib, and identified an allosteric site for inhibitor ...
12. 4qq5 (5,224 bytes)
    14: ...gh combining the salient inhibitory mechanisms of ponatinib and FIIN-2.
13. 4qqj (4,969 bytes)
    14: ...gh combining the salient inhibitory mechanisms of ponatinib and FIIN-2.
14. 4qqt (4,937 bytes)
    14: ...gh combining the salient inhibitory mechanisms of ponatinib and FIIN-2.
15. 4qrc (5,127 bytes)
    2: ...e Kinase Domain of FGF Receptor 4 in Complex with Ponatinib==
    14: ...gh combining the salient inhibitory mechanisms of ponatinib and FIIN-2.
16. 4twp (8,128 bytes)
    16: ...resistance to all approved ABL1 inhibitors except ponatinib, which has toxicity limitations. Here we combine ...
17. 4tyg (4,951 bytes)
    14: ...e I-inhibitor Dovitinib and the type II-inhibitor Ponatinib reveal the molecular interactions with different ...
18. 4tyi (5,019 bytes)
    14: ...e I-inhibitor Dovitinib and the type II-inhibitor Ponatinib reveal the molecular interactions with different ...
19. 4u0i (7,583 bytes)
    2: ==Crystal structure of KIT in complex with ponatinib==
    16: ...These data strongly support further evaluation of ponatinib in GIST patients.
    18: Ponatinib inhibits polyclonal drug-resistant KIT oncoprotei...
20. 4uxq (5,037 bytes)
    2: ==FGFR4 in complex with Ponatinib==
    14: ...d with kinetic characterization of the binding of ponatinib and AZD4547 to FGFR1 and FGFR4, sheds light on th...
    16: ...Selectivity: Diverse Binding Modes of AZD4547 and Ponatinib in Complex with FGFR1 and FGFR4.,Tucker JA, Klein...

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