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Article title matches
- Category:Prmt5 (36 bytes)
1: List of pages with the keyword Prmt5
Page text matches
- 2uwd (6,656 bytes)
24: ...vivin, and the protein arginine methyltransferase PRMT5. Both caused cell cycle arrest and apoptosis. Ext... - 4gqb (5,996 bytes)
2: ==Crystal Structure of the human PRMT5:MEP50 Complex==
13: ...beta-propeller MEP50 and the N-terminal domain of PRMT5, and delineates the structural elements of substr...
15: Crystal structure of the human PRMT5:MEP50 complex.,Antonysamy S, Bonday Z, Campbell R... - 9eyu (223 bytes)
7: Description: Human PRMT5 in complex with AZ compound 1 - 9eyv (224 bytes)
7: Description: Human PRMT5 in complex with AZ compound 12 - 9eyw (224 bytes)
7: Description: Human PRMT5 in complex with AZ compound 21 - 3ua3 (4,687 bytes)
2: ...l Structure of Protein Arginine Methyltransferase PRMT5 in complex with SAH==
17: ...the overall methylase activity, but also converts PRMT5 to an enzyme that catalyzes both symmetric and as...
19: ... into protein arginine symmetric dimethylation by PRMT5.,Sun L, Wang M, Lv Z, Yang N, Liu Y, Bao S, Gong ... - 3ua4 (3,703 bytes)
2: ...l Structure of Protein Arginine Methyltransferase PRMT5==
14: ...the overall methylase activity, but also converts PRMT5 to an enzyme that catalyzes both symmetric and as...
16: ... into protein arginine symmetric dimethylation by PRMT5.,Sun L, Wang M, Lv Z, Yang N, Liu Y, Bao S, Gong ... - 4a7j (4,365 bytes)
14: ... is also symmetrically dimethylated (H3R2me2s) by PRMT5 and PRMT7 and present in euchromatic regions. Pro... - 4g56 (4,406 bytes)
2: ==Crystal Structure of full length PRMT5/MEP50 complexes from Xenopus laevis==
13: ...ism in which MEP50 binds substrate and stimulates PRMT5 activity modulated by substrate post-translationa...
15: Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specifici... - 4x60 (4,166 bytes)
2: ==Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin== - 4x61 (4,169 bytes)
2: ==Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM== - 4x63 (5,779 bytes)
2: ==Crystal structure of PRMT5:MEP50 with EPZ015666 and SAH==
13: ...s a validated chemical probe for further study of PRMT5 biology and arginine methylation in cancer and ot...
15: A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.,... - 8g1u (5,757 bytes)
14: ... in the N-terminal region of Lsm11. Surprisingly, PRMT5 also methylates an N-terminal arginine in SmE, a ...
16: ...ion of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome.,Yang XC, Desotell A, Lin... - 5c9z (3,981 bytes)
2: ==Crystal structure of PRMT5:MEP50 with EPZ015866 and sinefungin== - 5emj (5,365 bytes)
2: ==Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin==
14: ...lective inhibitor of protein methyltransferase 5 (PRMT5) provides the scientific community with in vivo-a...
16: ...d Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.,Duncan KW, Rioux N, Bori... - 5emk (5,350 bytes)
2: ==Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin==
14: ...lective inhibitor of protein methyltransferase 5 (PRMT5) provides the scientific community with in vivo-a...
16: ...d Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.,Duncan KW, Rioux N, Bori... - 5eml (5,359 bytes)
2: ==Crystal structure of PRMT5:MEP50 with Compound 10 and SAM==
14: ...lective inhibitor of protein methyltransferase 5 (PRMT5) provides the scientific community with in vivo-a...
16: ...d Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.,Duncan KW, Rioux N, Bori... - 5emm (5,354 bytes)
2: ==Crystal structure of PRMT5:MEP50 with Compound 15 and sinefungin==
14: ...lective inhibitor of protein methyltransferase 5 (PRMT5) provides the scientific community with in vivo-a...
16: ...d Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.,Duncan KW, Rioux N, Bori... - 5fa5 (5,950 bytes)
2: ==Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide==
14: ...ed toward further PRMT5 inhibition. Inhibitors of PRMT5 that leverage this dysregulated metabolic state m...
16: ...TAP/CDKN2A deleted cancers leads to dependence on PRMT5.,Mavrakis KJ, McDonald ER 3rd, Schlabach MR, Bill... - 9eyx (224 bytes)
7: Description: Human PRMT5 in complex with AZ compound 28
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