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Article title matches

  1. Category:Prmt5 (36 bytes)
    1: List of pages with the keyword Prmt5

Page text matches

  1. 2uwd (6,656 bytes)
    24: ...vivin, and the protein arginine methyltransferase PRMT5. Both caused cell cycle arrest and apoptosis. Ext...
  2. 9n3n (5,516 bytes)
    2: ==Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 3=...
    14: ...G462, a more potent and selective MTA-cooperative PRMT5 inhibitor with improved DMPK properties that is s...
    16: ...62: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion.,C...
  3. 9n3o (3,894 bytes)
    2: ==Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 14...
    11: ... play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methyla...
    14: ...G462, a more potent and selective MTA-cooperative PRMT5 inhibitor with improved DMPK properties that is s...
    16: ...62: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion.,C...
  4. 9n3p (5,404 bytes)
    2: ==Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 30...
    14: ...G462, a more potent and selective MTA-cooperative PRMT5 inhibitor with improved DMPK properties that is s...
    16: ...62: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion.,C...
  5. 9n3q (5,364 bytes)
    2: ==Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 51...
    14: ...G462, a more potent and selective MTA-cooperative PRMT5 inhibitor with improved DMPK properties that is s...
    16: ...62: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion.,C...
  6. 9n3r (5,425 bytes)
    2: ==Crystal structure of PRMT5:MEP50 in complex with MTA and TNG462==
    14: ...G462, a more potent and selective MTA-cooperative PRMT5 inhibitor with improved DMPK properties that is s...
    16: ...62: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion.,C...
  7. 9ovy (340 bytes)
    7: Description: Cryo-EM structure of human PRMT5:MEP50 in complex with SAH and compounds 16-19F an...
  8. 9pca (6,335 bytes)
    2: ==HUMAN PRMT5:MEP50 COMPLEX IN COMPLEX WITH LIGAND 18==
    14: ...d evaluation workflow resulting in gut-restricted PRMT5 inhibitors. A two-pronged approach was envisioned...
    16: Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Pati...
  9. 4gqb (6,178 bytes)
    2: ==Crystal Structure of the human PRMT5:MEP50 Complex==
    14: ...beta-propeller MEP50 and the N-terminal domain of PRMT5, and delineates the structural elements of substr...
    16: Crystal structure of the human PRMT5:MEP50 complex.,Antonysamy S, Bonday Z, Campbell R...
  10. 9e3a (5,238 bytes)
    2: ==Cryo-EM structure of PRMT5/WDR77 in complex with 6S complex (pICln PBM local...
    13: ...te adaptor function and the biochemical nature of PRMT5 interactors.
    15: ...ate methylation by the arginine methyltransferase PRMT5.,Jin CY, Hunkeler M, Mulvaney KM, Sellers WR, Fis...
  11. 9e3b (3,278 bytes)
    2: ==Cryo-EM structure of PRMT5/WDR77 in complex with 6S complex==
    14: ...te adaptor function and the biochemical nature of PRMT5 interactors.
    16: ...ate methylation by the arginine methyltransferase PRMT5.,Jin CY, Hunkeler M, Mulvaney KM, Sellers WR, Fis...
  12. 9e3c (5,395 bytes)
    2: ==Cryo-EM structure of PRMT5/WDR77 in complex with 6S complex (GRG local refin...
    14: ...te adaptor function and the biochemical nature of PRMT5 interactors.
    16: ...ate methylation by the arginine methyltransferase PRMT5.,Jin CY, Hunkeler M, Mulvaney KM, Sellers WR, Fis...
  13. 9eyu (5,715 bytes)
    2: ==Human PRMT5 in complex with AZ compound 1==
    13: ... DMPK properties for oral dosing, and significant PRMT5-driven in vivo efficacy in several MTAP-deficient...
    15: ...very and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.,Smith JM, ...
  14. 9eyv (5,716 bytes)
    2: ==Human PRMT5 in complex with AZ compound 12==
    13: ... DMPK properties for oral dosing, and significant PRMT5-driven in vivo efficacy in several MTAP-deficient...
    15: ...very and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.,Smith JM, ...
  15. 9eyw (5,715 bytes)
    2: ==Human PRMT5 in complex with AZ compound 21==
    13: ... DMPK properties for oral dosing, and significant PRMT5-driven in vivo efficacy in several MTAP-deficient...
    15: ...very and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.,Smith JM, ...
  16. 9c10 (4,258 bytes)
    2: ==AMG 193, a clinical stage MTA-cooperative PRMT5 inhibitor, drives anti-tumor activity preclinical...
  17. 9nwy (2,536 bytes)
    2: ==Discovery of MTA-cooperative PRMT5 Inhibitors from Co-factor directed DNA-Encoded Li...
    11: ... play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methyla...
  18. 3ua3 (3,608 bytes)
    2: ...l Structure of Protein Arginine Methyltransferase PRMT5 in complex with SAH==
    12: ...the overall methylase activity, but also converts PRMT5 to an enzyme that catalyzes both symmetric and as...
    14: ... into protein arginine symmetric dimethylation by PRMT5.,Sun L, Wang M, Lv Z, Yang N, Liu Y, Bao S, Gong ...
  19. 3ua4 (3,703 bytes)
    2: ...l Structure of Protein Arginine Methyltransferase PRMT5==
    14: ...the overall methylase activity, but also converts PRMT5 to an enzyme that catalyzes both symmetric and as...
    16: ... into protein arginine symmetric dimethylation by PRMT5.,Sun L, Wang M, Lv Z, Yang N, Liu Y, Bao S, Gong ...
  20. 4a7j (4,365 bytes)
    14: ... is also symmetrically dimethylated (H3R2me2s) by PRMT5 and PRMT7 and present in euchromatic regions. Pro...

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