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  1. Category:Pyrimethamine (44 bytes)
    1: List of pages with the keyword Pyrimethamine

Page text matches

  1. 2bla (4,767 bytes)
    2: ... P. vivax Dihydrofolate reductase in complex with pyrimethamine==
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodi...
    26: ...of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resista...
  2. 2bl9 (4,672 bytes)
    2: ...ium vivax dihydrofolate reductase in complex with pyrimethamine and its derivative==
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodi...
    26: ...of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resista...
  3. 2blc (4,766 bytes)
    2: ...Dihydrofolate reductase in complex with des-chloropyrimethamine==
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodi...
    26: ...of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resista...
  4. 2blb (4,788 bytes)
    2: ...ium vivax dihydrofolate reductase in complex with pyrimethamine and its derivative==
    24: Pyrimethamine (Pyr) targets dihydrofolate reductase of Plasmodi...
    26: ...of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resista...
  5. Malarial Dihydrofolate Reductase as Drug Target (10,680 bytes)
    2: ...nih.gov/PyrimethamineSulfadoxine.htm>.</ref><ref>"Pyrimethamine and Sulfadoxine (Oral Route)." Mayo Clinic. Mayo ...
    4: ...ild-type PfDHFR-TS COMPLEXED WITH NADPH, dUMP AND PYRIMETHAMINE (PDB entry [[3qgt]])' scene=''>
    9: ... less of an effect on biological substrates. For pyrimethamine and cycloguanil specifically, the S108N mutation ...
    15: ...ke cycloguanil, was significantly more basic than pyrimethamine, a pyrimidine and slightly acidic substance to ma...
    25: ... a solution for the steric hindrance present with pyrimethamine because of its rigid chlorophenyl group. This anc...
  6. 1j3i (4,883 bytes)
    24: ...eatures for overcoming resistance. In contrast to pyrimethamine, the flexible side chain of WR99210 can adopt a c...
  7. 1j3j (4,866 bytes)
    2: ...e-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP==
    24: ...eatures for overcoming resistance. In contrast to pyrimethamine, the flexible side chain of WR99210 can adopt a c...
  8. 1j3k (4,913 bytes)
    24: ...eatures for overcoming resistance. In contrast to pyrimethamine, the flexible side chain of WR99210 can adopt a c...
  9. 1vj3 (5,811 bytes)
    24: ...nd two involving atropisomerism about the pivotal pyrimethamine-phenyl bond. The primary differences in the molec...
  10. Category:Pyrimethamine (44 bytes)
    1: List of pages with the keyword Pyrimethamine
  11. 3jsu (5,308 bytes)
    24: ...dihydrofolate reductase (DHFR) inhibitors-such as pyrimethamine (PM)-has now spread to almost all regions where m...
  12. 3lmy (3,225 bytes)
    2: ...tructure of beta-hexosaminidase B in complex with Pyrimethamine==
  13. 3qfx (2,260 bytes)
    2: ==Trypanosoma brucei dihydrofolate reductase pyrimethamine complex==
  14. 3qg2 (4,503 bytes)
    2: ...TS qradruple mutant (N51I+C59R+S108N+I164L, V1/S) pyrimethamine complex==
    14: ..., since none of the classical antifolates such as pyrimethamine (PYR), cycloguanil, or trimethoprim are effective...
  15. 3qgt (4,356 bytes)
    2: ...ild-type PfDHFR-TS COMPLEXED WITH NADPH, dUMP AND PYRIMETHAMINE==
    14: ..., since none of the classical antifolates such as pyrimethamine (PYR), cycloguanil, or trimethoprim are effective...
  16. 4dpd (4,982 bytes)
    14: ...ich is the basis for its high selectivity. Unlike pyrimethamine, P218 binds both wild-type and mutant PfDHFR in a...
  17. 4dph (5,155 bytes)
    14: ...ich is the basis for its high selectivity. Unlike pyrimethamine, P218 binds both wild-type and mutant PfDHFR in a...
  18. 4dp3 (5,100 bytes)
    14: ...ich is the basis for its high selectivity. Unlike pyrimethamine, P218 binds both wild-type and mutant PfDHFR in a...
  19. 3um5 (4,427 bytes)
    2: ...idylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP==
    14: ...confer resistance to cycloguanil (CYC) but not to pyrimethamine (PYR). In order to understand the nature of CYC r...
  20. 4ddr (5,770 bytes)
    16: ...ich is the basis for its high selectivity. Unlike pyrimethamine, P218 binds both wild-type and mutant PfDHFR in a...

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