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Article title matches
- Category:R132h (36 bytes)
1: List of pages with the keyword R132h - Category:Mutant r132h (43 bytes)
1: List of pages with the keyword Mutant r132h
Page text matches
- 9b81 (4,057 bytes)
16: ...pose how compounds binding in the allosteric IDH1 R132H pocket inhibit the production of 2-Hydroxy glutar... - 3inm (5,694 bytes)
2: ...osolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE... - 3map (4,891 bytes)
2: ==Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isoci...
16: ...onds to an initial ICT-binding state and that the R132H mutation can trap the enzyme in this conformation...
18: ...vities of human IDH1 by tumor-associated mutation R132H.,Yang B, Zhong C, Peng Y, Lai Z, Ding J Cell Res.... - 3mar (4,821 bytes)
2: ==Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isoci...
16: ...onds to an initial ICT-binding state and that the R132H mutation can trap the enzyme in this conformation...
18: ...vities of human IDH1 by tumor-associated mutation R132H.,Yang B, Zhong C, Peng Y, Lai Z, Ding J Cell Res.... - 3mas (4,893 bytes)
2: ==Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isoci...
16: ...onds to an initial ICT-binding state and that the R132H mutation can trap the enzyme in this conformation...
18: ...vities of human IDH1 by tumor-associated mutation R132H.,Yang B, Zhong C, Peng Y, Lai Z, Ding J Cell Res.... - 4kzo (4,978 bytes)
16: ... IDH1 as well as the known 2HG-producing clinical R132H and G97D mutants and mechanistic Y139D and (newly... - 4umx (4,971 bytes)
2: ==IDH1 R132H in complex with cpd 1==
16: ... A crystal structure of Compound 1 complexed with R132H IDH1 indicates that the inhibitor binds at the di... - 4umy (4,932 bytes)
2: ==IDH1 R132H in complex with cpd 1==
16: ... A crystal structure of Compound 1 complexed with R132H IDH1 indicates that the inhibitor binds at the di... - 8t7n (2,332 bytes)
2: ==Crystal structure of the R132H mutant of IDH1 bound to compound 1== - 8t7o (2,329 bytes)
2: ==Crystal structure of the R132H mutant of IDH1 bound to AG-120== - 5l57 (2,741 bytes)
2: ==Crystal structure of Iso-citrate Dehydrogenase R132H in complex with a novel inhibitor (compound 13a)=... - 5l58 (4,203 bytes)
2: ...l structure of Iso-citrate Dehydrogenase 1 [IDH1 (R132H)] in complex with a novel inhibitor (Compound 2)=...
16: ...uce myeloid differentiation in primary human IDH1 R132H AML cells in vitro.
18: ... Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid ... - 5lge (4,773 bytes)
2: ==Crystal Structure of human IDH1 mutant (R132H) in complex with NADP+ and an Inhibitor related t...
16: ...nsplanted with human astrocytoma carrying the IDH1R132H mutation. In conclusion, we developed a pan-inhib... - 5sun (2,806 bytes)
2: ==IDH1 R132H in complex with IDH146== - 5svf (2,697 bytes)
2: ==IDH1 R132H in complex with IDH125== - 5tqh (2,740 bytes)
2: ==IDH1 R132H mutant in complex with IDH889== - Category:R132h (36 bytes)
1: List of pages with the keyword R132h - 6b0z (2,756 bytes)
2: ==IDH1 R132H mutant in complex with IDH305== - User:Clara Fernández Vidal/Isocitrato deshidrogenasa (21,028 bytes)
21: ...vities of human IDH1 by tumor-associated mutation R132H. Cell Res. 2010 Nov;20(11):1188-200. doi: 10.1038...
185: ... ocurren principalmente en Arg132, y la mutación R132H es la más prevalente.
187: ...eacción catalítica; en particular, la mutación R132H dificulta los cambios conformacionales desde el e...
193: ...e se usó para el estudio de la mutación Arg132 (R132H) fue la IDH1 con código PDB 3MAS, con ligandos I... - 6adg (4,757 bytes)
2: ==Crystal Structures of IDH1 R132H in complex with AG-881==
16: ...ation times. Our data show that AG-881 binds IDH1-R132H and IDH2-R140Q in the same allosteric pockets and...
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