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- Simvastatin (5,359 bytes)
1: ...caption='Simvastatin, also known as Zocor' scene='Simvastatin/Just_simva/1'>
12: ....<ref>PMID:11349148</ref> These interactions help Simvastatin outcompete HMG-CoA, the substrate of HMGR, in bin...
27: ...reventing coronary heart disease compared to 20mg Simvastatin, but considering the variation in dosage level, i...
29: ...occurs in [[Atorvastatin]], [[Rosuvastatin]], and Simvastatin)<ref>PMID:20456733</ref> In March, 2010, the FDA ...
31: ...These results are even more pronounced for active Simvastatin metabolites. <ref>DOI: 10.1111/j.1365-2125.2004.... - Simvastatin Synthase (3,877 bytes)
1: ...'350' side='right' scene='' caption='Structure of Simvastatin Synthase complex with monacolin J acid and dithio...
30: ...h subsequently undergoes lactonization to yield [[Simvastatin]]<ref name="paper5">PMID:19875080</ref>.
33: LovD can also synthesize the blockbuster drug simvastatin using MJA and a synthetic α-dimethylbutyryl thio...
45: As simvastatin is an active pharmaceutical ingredient in the cho...
53: ==3D structures of simvastatin synthase== - Image:Simvastatin.gif (0 bytes)
- Category:Simvastatin (42 bytes)
1: List of pages with the keyword Simvastatin
Page text matches
- 9nmp (2,588 bytes)
2: ==Structure of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)== - 9nmq (3,093 bytes)
2: ==Structure of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)== - 9vl0 (3,796 bytes)
2: ==CYP105A1 complexed with simvastatin (cryogenic data collection)==
14: ...y acquired complex structures with mevastatin and simvastatin using room-temperature data collection with a con... - 3hl9 (5,995 bytes)
2: ==Simvastatin Synthase (LovD) from Aspergillus terreus, unligan...
10: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
12: [[Image:Consurf_key_small.gif|200px|right]]
23: ...ve the properties of LovD toward semisynthesis of simvastatin. Mutants with improved catalytic efficiency, solu...
25: ...ed evolution and structural characterization of a simvastatin synthase.,Gao X, Xie X, Pashkov I, Sawaya MR, Lai... - 3hlb (6,191 bytes)
2: ==Simvastatin Synthase (LovD) from Aspergillus terreus, unligan...
11: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...ve the properties of LovD toward semisynthesis of simvastatin. Mutants with improved catalytic efficiency, solu...
26: ...ed evolution and structural characterization of a simvastatin synthase.,Gao X, Xie X, Pashkov I, Sawaya MR, Lai... - 3hlc (4,627 bytes)
2: ==Simvastatin Synthase (LovD) from Aspergillus terreus, S5 muta...
11: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
13: [[Image:Consurf_key_small.gif|200px|right]]
24: *[[Simvastatin Synthase|Simvastatin Synthase]] - 3hld (6,327 bytes)
2: ==Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mut...
11: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...ve the properties of LovD toward semisynthesis of simvastatin. Mutants with improved catalytic efficiency, solu...
26: ...ed evolution and structural characterization of a simvastatin synthase.,Gao X, Xie X, Pashkov I, Sawaya MR, Lai... - 3hle (6,363 bytes)
2: ==Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mut...
11: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...ve the properties of LovD toward semisynthesis of simvastatin. Mutants with improved catalytic efficiency, solu...
26: ...ed evolution and structural characterization of a simvastatin synthase.,Gao X, Xie X, Pashkov I, Sawaya MR, Lai... - 3hlf (6,181 bytes)
2: ...lus terreus, S5 mutant, S76A mutant, complex with simvastatin==
7: ...ockDat" id="ligandDat"><scene name='pdbligand=SIM:SIMVASTATIN+ACID'>SIM</scene></td></tr>
11: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...ve the properties of LovD toward semisynthesis of simvastatin. Mutants with improved catalytic efficiency, solu... - 3hlg (6,306 bytes)
2: ==Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mut...
11: ...e specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptop...
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...ve the properties of LovD toward semisynthesis of simvastatin. Mutants with improved catalytic efficiency, solu...
26: ...ed evolution and structural characterization of a simvastatin synthase.,Gao X, Xie X, Pashkov I, Sawaya MR, Lai... - User:Eran Hodis/Sandbox PPT (888 bytes)
13: <scene name='HMG-CoA_Reductase/Statin_simva/5'>Simvastatin</scene> - Atorvastatin (4,760 bytes)
27: ... Atorvastatin reduces LDL about 2% more than 20mg Simvastatin despite having a lower IC<sub>50</sub> like due t...
29: ...ww.rxlist.com/lipitor-drug.htm</ref> Along with [[Simvastatin]] and [[Rosuvastatin]], taking atorvastatin was a... - Rosuvastatin (4,617 bytes)
29: ...y occurs in [[Atorvastatin]], Rosuvastatin, and [[Simvastatin]])<ref>PMID:20456733</ref> - HMG-CoA Reductase (11,205 bytes)
55: ...va/5'>simvastatin</scene> ([[1hw9]], [[Zocor]], [[Simvastatin]]), <scene name='HMG-CoA_Reductase/Statin_fluva/6... - Proteopedia:Structure Index/R-Z (13,484 bytes)
193: *** [[Simvastatin Synthase]] - User:Eran Hodis/Sandbox7 (10,845 bytes)
42: ...>, <scene name='HMG-CoA_Reductase/Statin_simva/3'>simvastatin (Zocor)</scene>, <scene name='HMG-CoA_Reductase/S... - Simvastatin (5,359 bytes)
1: ...caption='Simvastatin, also known as Zocor' scene='Simvastatin/Just_simva/1'>
12: ....<ref>PMID:11349148</ref> These interactions help Simvastatin outcompete HMG-CoA, the substrate of HMGR, in bin...
27: ...reventing coronary heart disease compared to 20mg Simvastatin, but considering the variation in dosage level, i...
29: ...occurs in [[Atorvastatin]], [[Rosuvastatin]], and Simvastatin)<ref>PMID:20456733</ref> In March, 2010, the FDA ...
31: ...These results are even more pronounced for active Simvastatin metabolites. <ref>DOI: 10.1111/j.1365-2125.2004.... - Zocor (24 bytes)
1: #REDIRECT[[Simvastatin]] - Statin Pharmacokinetics (1,335 bytes)
9: ! [[Simvastatin]] (Zocor) - User:David Canner/SandboxFunFunFun (888 bytes)
13: <scene name='HMG-CoA_Reductase/Statin_simva/5'>Simvastatin</scene>
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