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- Sitagliptin (3,135 bytes)
1: ... known as Januvia, ([[1x70]])' scene='Sitagliptin/Sitagliptin/1'>
12: ...nal dipeptides. <scene name='Sitagliptin/Bound/3'>Sitagliptin binds to the active site of DPP-4</scene> with gr... - Image:Sitagliptin.gif (0 bytes)
- Januvia (sitagliptin) (7,131 bytes)
1: ...Sitagliptin/Sitagliptin/1" align="right" caption="Sitagliptin (Januvia), ([[1x70]])"/>
4: ...ne> (Ser630, His740, and Asp708) and <scene name='Sitagliptin/Bound/1'>two glutamates</scene> (Glu205 and Glu20...
8: .../ref> Januvia is highly potent and a <scene name='Sitagliptin/Dpp4/2'>competitive inhibitor of the enzyme Dipep...
11: ...serine (S1) pocket</scene> and other <scene name='Sitagliptin/Hbond/2'>hydrogen bonding residues</scene>. Januv...
16: ..., M., et al. Double Edge Effect of DPP4 Inhibitor Sitagliptin, A Type-2 Anti-Diabetic Drug, on Inflammation, In...
Page text matches
- 4j3j (5,239 bytes)
14: ...d a subpocket different from the subsite bound by sitagliptin, providing clues for the design of new DPP4 inhib... - 7lkd (7,331 bytes)
13: ...e sites by in silico docking. We demonstrate that Sitagliptin and Daclatasvir inhibit PLpro, and MG-101, Lycori... - 7lke (7,329 bytes)
13: ...e sites by in silico docking. We demonstrate that Sitagliptin and Daclatasvir inhibit PLpro, and MG-101, Lycori... - 2iit (5,310 bytes)
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...l development as a potential back-up candidate to sitagliptin. - 2iiv (5,161 bytes)
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ...l development as a potential back-up candidate to sitagliptin. - 2p8s (5,241 bytes)
13: [[Image:Consurf_key_small.gif|200px|right]]
24: ... of sitagliptin 1. The X-ray crystal structure of sitagliptin bound to DPP-4 suggested that the central beta-am...
26: ...f molecular modeling and X-ray crystallography of sitagliptin.,Biftu T, Scapin G, Singh S, Feng D, Becker JW, E... - 3w2t (5,305 bytes)
14: ... in addition to the S1 and S2 subsites; and (iii) sitagliptin and teneligliptin (Class 3) form interactions wit... - Treatments:Diabetes (1,091 bytes)
10: ...] - Generic: [[Sitagliptin]]; see also [[Januvia (sitagliptin)]] - Dipeptidyl Peptidase-4 Inhibitor Pharmacokinetics (1,251 bytes)
7: ! [[Sitagliptin]]<br/>(Januvia) - Vildagliptin (2,422 bytes)
12: ... it is believed to bind in a similar fashion to [[Sitagliptin]] and [[Saxagliptin]]. - Sitagliptin (3,135 bytes)
1: ... known as Januvia, ([[1x70]])' scene='Sitagliptin/Sitagliptin/1'>
12: ...nal dipeptides. <scene name='Sitagliptin/Bound/3'>Sitagliptin binds to the active site of DPP-4</scene> with gr... - Saxagliptin (3,179 bytes)
8: ...eness at nearly 20-fold lower doses compared to [[Sitagliptin]] & [[Vildagliptin]], allowing for dramatically r... - Januvia (24 bytes)
1: #REDIRECT[[Sitagliptin]] - Dipeptidyl peptidase (2,023 bytes)
14: *[[Sitagliptin]] - 4ffw (3,175 bytes)
2: ...ase IV (DPP4, DPP-IV, CD26) in Complex with Fab + sitagliptin== - Sandbox Reserved 918 (13,357 bytes)
20: ... here, <scene name='57/573132/1x70_sitagliptin/3'>Sitagliptin</scene>, is a common drug used to inhibit DPP IV....
58: ...strate, [http://en.wikipedia.org/wiki/Sitagliptin Sitagliptin]. Based off of the crystal structure, this tyrosi...
67: ...II diabetes in addition to DPP IV inhibitors like sitagliptin. <ref name="Scheen"/> - Dipeptidyl peptidase IV (13,763 bytes)
20: ... here, <scene name='57/573132/1x70_sitagliptin/3'>Sitagliptin</scene>, is a common drug used to inhibit DPP IV....
58: ...strate, [http://en.wikipedia.org/wiki/Sitagliptin Sitagliptin]. Based off of the crystal structure, this tyrosi...
67: ...II diabetes in addition to DPP IV inhibitors like sitagliptin. <ref name="Scheen"/> - 3wwh (3,559 bytes)
14: ... surface properties, to accommodate the large pro-sitagliptin ketone. Our findings provide a detailed explanati... - 3wwi (3,488 bytes)
14: ... surface properties, to accommodate the large pro-sitagliptin ketone. Our findings provide a detailed explanati... - 3wwj (3,554 bytes)
2: ==Crystal structure of an engineered sitagliptin-producing transaminase, ATA-117-Rd11==
14: ... surface properties, to accommodate the large pro-sitagliptin ketone. Our findings provide a detailed explanati...
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