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Article title matches

  1. Category:T315i abl mutant (47 bytes)
    1: List of pages with the keyword T315i abl mutant
  2. Category:T315i (36 bytes)
    1: List of pages with the keyword T315i

Page text matches

  1. 2v7a (8,542 bytes)
    2: ==Crystal structure of the T315I Abl mutant in complex with the inhibitor PHA-7393...
    26: ...ants, including T315I. The cocrystal structure of T315I Abl kinase domain provides the structural basis f...
    28: Crystal structure of the T315I Abl mutant in complex with the aurora kinases inh...
  2. 2z60 (6,878 bytes)
    2: ==Crystal Structure of the T315I Mutant of Abl kinase bound with PPY-A==
    24: ...design of clinically useful inhibitors of Bcr-AbI T315I.
    26: Crystal structure of the T315I mutant of AbI kinase.,Zhou T, Parillon L, Li F, W...
  3. 2f4j (8,815 bytes)
    26: ...t inhibitory activity against BCR-Abl bearing the T315I mutation in patient-derived samples. The Abl kina...
  4. 2qoh (6,858 bytes)
    24: ...design of clinically useful inhibitors of Bcr-AbI T315I.
    26: Crystal structure of the T315I mutant of AbI kinase.,Zhou T, Parillon L, Li F, W...
  5. SandboxPKA (24,333 bytes)
    126: ...gainst most BCR-ABL mutants with the exception of T315I. <ref>PMID: 15256671</ref> Dasatinib is well tole...
    142: ...he side chain of I315, allowing inhibition of the T315I mutant. The triple bond also acts as an inflexibl...
    158: 3. '''T315I mutation''': In the presence of Imatinib, cells t...
    172: ... important to underline that all mutations except T315I were effectively suppressed by increasing Nilotin...
    186: ... intolerant to TKIs or have mutations such as the T315I mutation, which can produce significant resistanc...
  6. Category:T315i abl mutant (47 bytes)
    1: List of pages with the keyword T315i abl mutant
  7. Category:T315i (36 bytes)
    1: List of pages with the keyword T315i
  8. 3dqw (6,042 bytes)
    24: ...d 14) inhibits the gatekeeper mutation of BCR-ABL-T315I. These results demonstrate that mutation of the g...
  9. 3dqx (5,900 bytes)
    24: ...d 14) inhibits the gatekeeper mutation of BCR-ABL-T315I. These results demonstrate that mutation of the g...
  10. 2w1c (6,639 bytes)
    24: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  11. 2w1e (6,572 bytes)
    24: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  12. 2w1d (6,514 bytes)
    24: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  13. 2w1f (6,531 bytes)
    24: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  14. 2w1g (6,644 bytes)
    24: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  15. 2w1h (7,713 bytes)
    24: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  16. 2w1i (9,430 bytes)
    26: ...a number of other kinases including JAK2 and Abl (T315I). This compound demonstrated in vivo efficacy in ...
  17. 3ik3 (6,815 bytes)
    2: ...r Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance==
    24: ...llular and biochemical assays, suppressed BCR-ABL(T315I)-driven tumor growth in mice, and completely abro...
    26: ...r chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance.,O...
  18. 3k5v (7,130 bytes)
    24: ...tivity in biochemical and cellular assays against T315I mutant human Bcr-Abl and displayed in vivo effica...
  19. Nilotinib (3,614 bytes)
    13: ...nt versions of BCR-Abl, with the exception of the T315I mutant. <ref>PMID:16172030</ref> In BCR-Abl, <sce...
  20. 3kf4 (7,362 bytes)
    24: ...DFG-out class inhibitors against Src, Abl and Abl T315I mutant kinases.

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