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Article title matches

  1. Category:Trem2 (36 bytes)
    1: List of pages with the keyword Trem2

Page text matches

  1. 9npo (262 bytes)
    7: Description: CRYSTAL STRUCTURE OF MBP-TREM2 IG DOMAIN FUSION WITH ABETA 1-8 peptide
  2. 9nol (268 bytes)
    7: Description: Crystal structure of MBP-TREM2 N79Q Ig domain fusion
  3. Gamma secretase (20,920 bytes)
    14: ...ch as Notch, E-cadherin, ErbB4, CD44, tyrosinase, TREM2 and Alcadein, suggesting the participation of γ-...
  4. 5eli (3,908 bytes)
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    16: ...of TREM2, indicating that therapies targeting the TREM2 pathway should be tailored to these genetic and f...
    18: Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-...
  5. Category:Trem2 (36 bytes)
    1: List of pages with the keyword Trem2
  6. 5ud7 (4,335 bytes)
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    16: ...l how decreased in vitro and in vivo stability of TREM2 contribute to loss of function in disease.
    18: ...se-associated R47H variant of the immune receptor TREM2.,Sudom A, Talreja S, Danao J, Bragg E, Kegel R, M...
  7. 5ud8 (4,042 bytes)
    10: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    12: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    15: ...l how decreased in vitro and in vivo stability of TREM2 contribute to loss of function in disease.
    17: ...se-associated R47H variant of the immune receptor TREM2.,Sudom A, Talreja S, Danao J, Bragg E, Kegel R, M...
  8. 6b8o (4,443 bytes)
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    16: ...l how decreased in vitro and in vivo stability of TREM2 contribute to loss of function in disease.
    18: ...se-associated R47H variant of the immune receptor TREM2.,Sudom A, Talreja S, Danao J, Bragg E, Kegel R, M...
  9. 6y6c (3,816 bytes)
    2: ==TREM2 extracellular domain (19-174) in complex with sin...
    12: ...rs as structural and functional biology tools for TREM2 research.
    14: Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.,Szyk...
  10. 6ymq (4,454 bytes)
    2: ==TREM2 extracellular domain (19-131) in complex with sin...
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    16: ...rs as structural and functional biology tools for TREM2 research.
    18: Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.,Szyk...
  11. 6yye (4,456 bytes)
    2: ==TREM2 extracellular domain (19-131) in complex with sin...
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    16: ...rs as structural and functional biology tools for TREM2 research.
    18: Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.,Szyk...
  12. 6z0g (2,817 bytes)
    2: ==Structure of TREM2 transmembrane helix in DPC micelles==
    11: ... a charged amino acid in the membrane region, the TREM2-TMH adopts a kinked structure with increased flex...
    13: ...a-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamic...
  13. 6z0h (2,831 bytes)
    2: ==Structure of TREM2 transmembrane helix K186A variant in DPC micelles...
    11: ... a charged amino acid in the membrane region, the TREM2-TMH adopts a kinked structure with increased flex...
    13: ...a-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamic...
  14. 6z0i (2,843 bytes)
    2: ==Structure of the TREM2 transmembrane helix in complex with DAP12 in DPC ...
    11: ... a charged amino acid in the membrane region, the TREM2-TMH adopts a kinked structure with increased flex...
    13: ...a-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamic...
  15. 6xds (3,360 bytes)
    2: ==Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl...
    12: ...l utility of this system for the discovery of new TREM2 therapeutics.
    14: ...bust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.,Byrne...
  16. 7y4p (4,939 bytes)
    13: ...ng events in the cytoplasm. Acts as coreceptor of TREM2 for SEMA6D in dendritic cells and is involved in ...
  17. 7y4q (5,095 bytes)
    13: ...ng events in the cytoplasm. Acts as coreceptor of TREM2 for SEMA6D in dendritic cells and is involved in ...
  18. 8t51 (2,422 bytes)
    2: ==Crystal structure of Fab 3.10C2 bound to TREM2==
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
  19. 8t59 (2,421 bytes)
    2: ==Crystal structure of Para.09 bound to TREM2==
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
  20. 9pwn (4,927 bytes)
    2: ==Crystal structure of Fabs 7411 in complex with TREM2 peptide==
    11: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic...
    13: [https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations a...
    16: ...body with low effector function that can modulate TREM2 signaling in vitro and brain pharmacodynamic resp...
    18: Building a potent TREM2 agonistic, biparatopic, common light chain antibo...

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