Displaying the mutated structure on SARS-COV-2 viral particle's spike protein, based on entry: '6vyb'.
SpikeProteinStructureHZ.
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Click the green text to bring up the fine structure: the newly acquired mutations, are located in the "interfacing" zone: upon cell entry, spots viral particle motifs contact ACE2.
We also provide another enhanced structural illustration below:
Full resolution can be found here
https://proteopedia.org/wiki/index.php/Image:SPG_Substructure_6VSB_new_mutations.png
Function
Cell entry: Here is a simple demonstration that the newly acquired mutations in Omicron variant (OV) are located in the "interfacing" zone.
Disease
CoV-19 Disease Antigen co-conspirator: the OV's general fitness has a root cause, as we discussed.
Relevance
Structural highlights
SARS-CoV-2 Spike Protein with 4 highlighted OV mutations.
