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Talk:Rossmann fold
From Proteopedia
Ideas for improvement
This "figure-review" was written by Emily Cappucci as part of an assignment for a Biochemistry course at Westfield State University, and posted here by the instructor with permission.
- My favorite figure: My favorite figure is figure 5, “3-phosphoglycerate dehydrogenase beta sheet in the NAD binding domain”. This static figure is based on the coordinates 2p9e. A similar 3D scene is shown as well, based on the script: http://proteopedia.org/wiki/scripts/59/595757/Ferredoxin-reductase-fad/2.spt. The page is featured in a BAMBED article from 2015 available at https://iubmb.onlinelibrary.wiley.com/doi/10.1002/bmb.20849
- This is my suggestion for a figure legend: The Rossmann fold of 3-phosphoglycerate dehydrogenase is shown with continuous segment of β-sheets and alpha helices. The direction of the strands are all parallel which represents a general trend in Rossmann folds.
- What I like about the figure: This is the best figure to show an example of the Rossmann Fold, a super-secondary structure. The figure does an excellent job showing the extension of the continuous -stands and alternating pattern of -strand-alpha helix- β strand secondary structures.
- Corresponding figure in the primary citation: In the primary citation, figure 2 shows the orientation of the β‐strands in the Rossmann fold of the NADP binding site of methylene‐ tetrahydromethanopterin dehydrogenase. This figure is also a clear representation of the Rossmann fold showing the continuous β‐strands and alpha helices.
- How I think the figure could be improved: I really wished this was one of the 3D figures so that I could interact and rotate the figure to see the other angles. If this figure was interactive and had more examples specific to this structure I think it would be the perfect figure.
--Karsten Theis 20:47, 20 December 2018 (UTC)
