Template:STRUCTURE 3dxc
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Asymmetric Unit
Biological Assembly
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3dxc
,
resolution
2.10Å ()
Gene
:
APBB1, FE65, RIR (
Homo sapiens
), APP, A4, AD1 (
Homo sapiens
)
Related
:
3dxd
,
3dxe
Structural annotation
:
Resources:
InterPro :
Ipr001202
,
Ipr006020
,
Ipr011993
,
Ipr002223
,
Ipr008154
,
Ipr008155
,
Ipr011178
,
Ipr013803
,
Ipr015849
Pfam :
PF00640
UniProt :
O00213
,
P05067
Functional annotation
:
Cellular component
:
nucleus
lamellipodium
synapse
growth cone
extracellular region
integral to membrane
integral to plasma membrane
platelet alpha granule lumen
coated pit
cell surface
membrane
Biological process
:
signal transduction
regulation of transcription
negative regulation of cell growth
axonogenesis
cell cycle arrest
negative regulation of thymidylate synthase biosynthetic process
negative regulation of S phase of mitotic cell cycle
cell adhesion
apoptosis
endocytosis
cellular copper ion homeostasis
Notch signaling pathway
neuromuscular process
Molecular function
:
beta-amyloid binding
transcription factor binding
protein binding
heparin binding
endopeptidase inhibitor activity
metal ion binding
binding
identical protein binding
zinc ion binding
copper ion binding
acetylcholine receptor binding
iron ion binding
serine-type endopeptidase inhibitor activity
Evolutionary conservation
:
Toggle Conservation Colors:
Rows = identical sequences:
Further Information:
Caveats
,
Explanation
,
Complete Results at ConSurfDB
Resources:
FirstGlance
,
OCA
,
RCSB
,
PDBsum
Coordinates
:
save as
pdb
,
mmCIF
,
xml
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