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HRP1 found in Saccharomyces cerevisiae

Introduction

Contents

Hrp1 is a heterogeneous ribonuclear protein of Saccharomyces cerevisiae, baker’s yeast. Hrp1 is an essential component of 3’ pre-mRNA processing and contributes to the preparatory cleavage required for polyadenylation. The gene expressed as Hrp1, HRP1, was first isolated by Henry, et al.[1] and was later attributed to the Hrp1 protein by Kessler, et al.[2] Hrp1 also participates in the regulation of the 3’ end. The structure was solved via NMR by Pérez-Cañadillas.[3]

(PDB entry 2cjk)

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Clayton Moore

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