User:Cody Couperus/Sandbox 3
From Proteopedia
Contents |
RNA
Introduction
-single stranded polynucleic acid
-Transcribed from DNA by family of RNA polymerases
-Functional roles include functional transfer for protein synthesis, catalysis, cellular regulation
-Degraded by....
Products of Transcription
Names/functional roles
Post/Co-transcriptional modifications
Degradation pathways
Structure General
Summary of - how to build a 3D structure from a linear medium. Practical considerations. How to think about folded polymers.
Backbone
Ribose
Bases + base pairing
Forces: stacking (VDW), hydrogen bond, hydrophobic effect, electrostatic
Primary Structure
Sequence
Maybe some statistics?
Structure (building blocks)
Stem loop
Coaxial helices
Kink-turn
Hook-turn
Ribose zipper
Kissing loops
Hairpin loops
Pseudoknots
A-minor interactions
A-major interactions
Tetraloop-receptor motifs
T-loop motif
Triple stranded RNA
RNA quadruplex structuers
Metal chelation
