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Contents 1 Vitamin K Epoxide Reductase 1.1 Introduction 1.2 Function 1.2.1 Catalytic Mechanism 1.3 Disease 1.4 Relevance 1.5 Structural highlights 1.5.1 HsVKOR 1.5.2 TrVKOR 1.6 References 1.7 Student Contributors

Vitamin K Epoxide Reductase

spinqualitylabelsall models PDB ID 6WV4 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Introduction

Overview of the vitamin K epoxide reductase structure and function^[1]

Open conformation of VKOR

Function

Structure and Function

Catalytic Mechanism

Disease

Relevance

Structural highlights

HsVKOR

TrVKOR

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This is a default text for your page George G. Papadeas/Sandbox 1. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia ^[2] or to the article describing Jmol ^[3] to the rescue.

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References

^[1]

1. ↑ ^{1.0 1.1} Tie JK, Stafford DW. Structure and function of vitamin K epoxide reductase. Vitam Horm. 2008;78:103-30. doi: 10.1016/S0083-6729(07)00006-4. PMID:18374192 doi:http://dx.doi.org/10.1016/S0083-6729(07)00006-4
2. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
3. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

Student Contributors

• George G. Papadeas
• Anna Pressel